Abstract: Embodiments improve the ability of users of a social networking system to search for information that is likely to be relevant to them by learning and/or applying a search context associated with selector components used to search for objects of the social networking system. The search context is specific to the use of an individual selector and thus need not be as general as the context of an entire page or set of pages in which selectors can be embedded. The social networking system may learn the context of a selector by monitoring user selections from prior search results performed using the selector.

Abstract: Disclosed is a method for sequencing a polynucleotide analyte comprising:•a. generating a stream of droplets containing a single nucleotide wherein the order of single nucleotides in the droplet stream corresponds to the sequence of nucleotides in the analyte;•b. introducing into each droplet a plurality of biological probe types each type comprising a different label in an undetectable state and being adapted to capture a different single nucleotide;•c. causing the single nucleotide contained in the droplet to bind to its complementary probe and•d. causing the label to be released from the probe that has bound the nucleotide in a detectable state. The probe is a dumbbell shaped probe comprising fluorescent donor and quencher labels and a single nucleotide gap. After gap repair by a polymerase and a ligase, a restriction enzyme recognition site is cleaved by a restriction enzyme, followed by exonuclease digestion to release the labels.

Abstract: Disclosed is a method for determining the sequence of nucleotide bases in a polynucleotide analyte characterised by the steps of: a. generating a stream of droplets at least some of which contain a single nucleotide and wherein the order of single nucleotides in the droplet stream corresponds to the sequence of nucleotides in the analyte; b. introducing into each droplet a plurality of biological probe types each type (i) comprising a different detectable element in an undetectable state and (ii) being adapted to capture a different complimentary single nucleotide from which the analyte is constituted; c. causing the single nucleotide contained in the droplet to bind to its complimentary probe to create a used probe and d. causing the detectable element to be released from the used probe in a detectable state.

Abstract: The present invention provides an apparatus for analysing the sequence of nucleotides in a nucleic acid sample, said apparatus comprising a substrate and a plurality of nanopores provided therein suitable for the passage of nucleic acid molecules therethrough; at least one sample holding chamber disposed upstream of the inlet of said nanopores, at least one detection window juxtaposed within or downstream of the outlet of each nanopore adapted to detect a property characteristic of one or more detectable elements associated with the nucleic acid as each nucleic acid molecule passes therethrough and a detector adapted to generate a data stream characteristic of the various detection events occurring in the detection window characterised in that the apparatus further comprises a means located within the sample holding chamber adapted to increase the local concentration of the nucleic acid sample adjacent the inlet of the nanopores relative to the bulk concentration thereof.

Abstract: A social networking system leverages user's social information to evaluate content submitted for inclusion in objects. If the evaluated submission is accepted, the submission is added to the content of an object. Accepted submissions are also used to predict associations between metadata and objects. Metadata is used to predict which objects will match user searches for information. The social networking system also provides a user interface configured to prompt users to submit information to objects. When a user completes a submission to an object, the user is provided with other options for groups of objects to contribute to. The objects offered are chosen to increase the likelihood that the user will choose to provide submissions to one of the provided objects.

Abstract: A social networking system leverages user's social information to evaluate content submitted for inclusion in objects. If the evaluated submission is accepted, the submission is added to the content of an object. Accepted submissions are also used to predict associations between metadata and objects. Metadata is used to predict which objects will match user searches for information. The social networking system also provides a user interface configured to prompt users to submit information to objects. When a user completes a submission to an object, the user is provided with other options for groups of objects to contribute to. The objects offered are chosen to increase the likelihood that the user will choose to provide submissions to one of the provided objects.

Abstract: Equivalent concepts expressed across multiple domains are matched and associated with a metapage generated by a social networking system. User preferences expressed on multiple domains, represented as pages in a social networking system, may be organized by concept and shared with advertisers, third-party developers, and other users of the social networking system using the metapages generated for the concepts. Aggregated social information may be presented to users of the social networking system viewing a page associated with a metapage. Information presented on external websites may be used to link pages across multiple domains with a metapage generated on the social networking system. In one embodiment, the information on other external websites associated with the metapage may be presented as links on the pages associated with the metapage. Feedback from users may be used to include or exclude pages from being associated with a generated metapage.

Abstract: A method for mapping the number and location of restriction enzymes sites for a given restriction enzyme in a target nucleic acid comprises the steps of (1) translocating a target nucleic acid having detectable elements characteristic of the presence of the restriction enzyme sites therein through an analysing device comprising a nanopore and a detection window and (2) causing the detectable elements to be detected as they pass though the detection window. Typically the detectable elements are formed by attaching to the restriction enzyme sites a restriction enzyme to which one or more marker moieties have been added. The data or signal obtained from the detection is suitably in the form of a distribution profile of the detectable elements, and therefore the restriction enzyme sites along the length of the target nucleic acid and can be used to create a reference set of like distribution profiles against which new distributions can be compared.

Abstract: Equivalent concepts expressed across multiple domains are matched and associated with a metapage generated by a social networking system. User preferences expressed on multiple domains, represented as pages in a social networking system, may be organized by concept and shared with advertisers, third-party developers, and other users of the social networking system using the metapages generated for the concepts. Aggregated social information may be presented to users of the social networking system viewing a page associated with a metapage. Information presented on external websites may be used to link pages across multiple domains with a metapage generated on the social networking system, presenting the information on other external websites associated with the metapage as links on the pages associated with the metapage. Feedback from users may be used to include or exclude pages from being associated with a generated metapage.

Abstract: The invention provides polymer particles that are obtainable by a method selected from emulsion methods, diffusion methods and evaporation methods carried out in the presence of surface-engineering surfactant which is one or more polymer that displays a lower critical solution temperature, in aqueous media, that is between 10 to 90° C., this polymer being the polymerization product of one or more monomer selected from polymerisable alkyleneglycol acrylate monomers and polymerisable alkyleneglycol methacrylate monomers. The polymer particles can be used in controlled release applications, such as flavour release applications, fragrance release applications and biomedical applications. The invention also provides a cell support matrix comprising the polymer particles.

Abstract: In one embodiment, a method includes accessing a social graph comprising a plurality of nodes and a plurality of edges connecting the nodes, each node corresponding to a user of an online social network, identifying a plurality of clusters in the social graph using graph clustering, providing a treatment to a first set of users based on the clusters, and determining a treatment effect treatment for the users in the first set based on a network exposure to the treatment for each user.

Abstract: Embodiments of the invention improve the ability of a social networking system to determine which types of data—hereinafter referred to as “fields”—are relevant to which types of user pages. Specifically, a social networking system assigns page types to different user pages, and likewise stores information on different types of fields. By analyzing the relationships of different pages and fields, the social networking system determines which types of fields are particularly well-suited for inclusion on different types of pages. Using the learned information about page types and field types, the social networking system can better aid page administrators in specifying data to add to their pages. For example, the social networking system can recommend to administrators the addition of certain types of fields or automatically add the fields. Further, the social networking system can specialize a search for social networking system data to field types.

Abstract: A method for identifying a target polymer (20) comprises translocating a target polymer (20) having detectable elements (22), such as fluorophores (22), through an analysing device (24) comprising a nanopore (28) having a detection window (40), wherein the analysing device (24) is capable of plasmon resonance to produce a localised electromagnetic field which defines the detection window (40) detecting the detectable elements (22) as they pass through the detection window (40) to produce a distribution profile of the detectable elements (22) along the target polymer (20) and identifying the target polymer (20) by comparing the distribution profile to a reference set of distribution profiles for known polymers. In a preferred embodiment the target polymer (20) is a nucleic acid and the detectable elements (22) are oligonucleotides complimentary to at least two adjacent nucleotides therein. Exemplified is the use of 6-mer oligonucleotides.

Abstract: A social networking system provides an instruction that a third-party system may include in a web page or other content. The instruction includes information identifying content presented by the web page or other content specified by the third-party system. The information identifying the content presented by the web page is communicated to the social networking system. Based on the information identifying the content, the social networking system determines a social context for a viewer of the web page. The social context may be selected to optimize for a particular conversion event.

Abstract: In particular embodiments a social networking system captures data associated with video content provided to a first user of a social-networking system, identifies, using the captured data, the video content provided to the first user, and updates a graph of the social-networking system to associate the first user with the identified video content. The graph of the social-networking system has a plurality of nodes and edges connecting the nodes. The nodes of the graph include user nodes that are each associated with a particular user of the social-networking system.

Abstract: In particular embodiments, one or more computer systems of a social-networking system determine information associated with a product displayed on a display device and access a database of known products. The one or more computer systems of the social-networking system determine, by comparing the database of known products with the determined information associated with the product, an identity of the product displayed on the display device. The one or more computer systems of the social-networking system provide one or more instructions to display media content related to the identified product.

Abstract: In particular embodiments a social networking system may receive authorization from a first user of a social-networking system to control at least in part one or more functions of a set-top box (STB) of the first user, determine one or more social actions of one or more second users of the social-networking system, determine one or more instructions for the STB of the first user based at least in part on the social actions, and provide the instructions for the STB of the first user. The social-networking system includes a graph having a plurality of nodes and edges connecting the nodes.

Abstract: In particular embodiments, one or more computer systems of a social-networking system identify a user viewing video content on a first display device, identify the video content being viewed on the first display device by the user, and determine a second display device associated with the identified user. The one or more computer systems of the social-networking system determine an action related to the video content being viewed by the user on the first display device and provide one or more instructions to the determined second display device to display a call-to-action associated with the determined action.

Abstract: In particular embodiments, a social networking system identifies a user viewing video content on a first display device, identifies the video content being viewed on the first display device by the user, and determines a second display device associated with the identified user. The social networking system sends one or more instructions to the determined second display device to display one or more chat messages associated with the identified video content.

Abstract: In particular embodiments, one or more computer systems of a social-networking system determine identities of one or more users in proximity to a display device and query a social graph of the social-networking system for social content associated with the determined identities. The social graph includes nodes and edges connecting the nodes. The nodes include user nodes that are each associated with a particular user of the social-networking system. The one or more computer systems of the social-networking system identify, using the social content, recommended media content for the one or more users in proximity to the display device and provide a playlist for display on the display device. The playlist includes the recommended media content for the one or more users in proximity to the display device.