Abstract: Systems and methods are disclosed that include an electronic device and an activation device. The electronic device includes a battery compartment having a battery storage section and a battery engagement section. The battery engagement section includes battery contacts. The electronic also includes a battery disposed in the battery storage section of the battery compartment. The battery moves from the battery storage section to the battery engagement section in response to an activation event to place the battery in electrical contact with the battery contacts. The activation device includes an activation element configured to generate the activation event.

Abstract: A method in a computing device includes: capturing, via a camera of a computing device, an image of a monitoring device including a sensor, the sensor presenting an active one of a set of predefined visual states; detecting, within the image, a machine-readable indicium disposed on the monitoring device; determining, from the machine-readable indicium, a state detection parameter; selecting, according to the state detection parameter, at least portion of the image containing the sensor and determining the active state presented by the sensor; controlling an output assembly of the computing device to present a handling notification based on the determined active state.

Abstract: Systems and methods are disclosed that include an electronic device and an activation device. The electronic device includes a battery compartment having a battery storage section and a battery engagement section. The battery engagement section includes battery contacts. The electronic also includes a battery disposed in the battery storage section of the battery compartment. The battery moves from the battery storage section to the battery engagement section in response to an activation event to place the battery in electrical contact with the battery contacts. The activation device includes an activation element configured to generate the activation event.

Abstract: Systems and methods are disclosed that include an electronic device and an activation device. The electronic device includes a battery compartment having a battery storage section and a battery engagement section. The battery engagement section includes battery contacts. The electronic also includes a battery disposed in the battery storage section of the battery compartment. The battery moves from the battery storage section to the battery engagement section in response to an activation event to place the battery in electrical contact with the battery contacts. The activation device includes an activation element configured to generate the activation event.

Abstract: A method, system, and apparatus are provided that include: receiving an electronic record including health information that is associated with an individual and receiving historical data about the health information including changes in the health information recorded over time. The method, system, and apparatus further include determining, based on the historical data and the changes in the health information recorded over time received, that a change to at least one of a structured diet plan, a lifestyle behavior, and a prescribed drug is available for the individual, and updating the electronic record to store the change.

Abstract: A method in a computing device includes: capturing, via a camera of a computing device, an image of a monitoring device including a sensor, the sensor presenting an active one of a set of predefined visual states; detecting, within the image, a machine-readable indicium disposed on the monitoring device; determining, from the machine-readable indicium, a state detection parameter; selecting, according to the state detection parameter, at least portion of the image containing the sensor and determining the active state presented by the sensor; controlling an output assembly of the computing device to present a handling notification based on the determined active state.

Abstract: A method in a computing device includes: capturing, via a camera of a computing device, an image of a monitoring device including a sensor, the sensor presenting an active one of a set of predefined visual states; detecting, within the image, a machine-readable indicium disposed on the monitoring device; determining, from the machine-readable indicium, a state detection parameter; selecting, according to the state detection parameter, at least portion of the image containing the sensor and determining the active state presented by the sensor; controlling an output assembly of the computing device to present a handling notification based on the determined active state.

Abstract: A method in a computing device includes: capturing, via a camera of a computing device, an image of a monitoring device including a sensor, the sensor presenting an active one of a set of predefined visual states; detecting, within the image, a machine-readable indicium disposed on the monitoring device; determining, from the machine-readable indicium, a state detection parameter; selecting, according to the state detection parameter, at least portion of the image containing the sensor and determining the active state presented by the sensor; controlling an output assembly of the computing device to present a handling notification based on the determined active state.

Abstract: The present invention provides compounds of Formula (I) and pharmaceutical compositions comprising compounds of Formula I, and methods for using compounds of Formula I for treating or preventing thromboses, embolisms, hypercoaguability or fibrotic changes.

Abstract: The present invention provides a compound of Formula (I) wherein R1 is H or C1-6 alkyl, R2, is H or C1-6 alkyl or CH2OH, R3 is H or C1-6 alkyl, and R4 is H or C1-6 alkyl, provided that when R1, R2, and R3 are H, R4 is C1-6 alkyl, and when R1, R2, and R4 are H, then R3 is C1-6 alkyl, and when R1, R3, and R4 are H, R2 is C1-6 alkyl or —CH2OH, and when R2, R3, and R4 are H, then R1 is C1-6 alkyl; A is 1) a 9-10 membered bicyclic heterocycle having 1-3 heteroatoms independently selected from N, S and O, which 9-10 membered bicyclic heterocycle is unsubstituted or substituted with R5 and unsubstituted or substituted with R6 and unsubstituted or substituted with NH2, or 2) a 6-9 membered monocyclic or bicyclic carbocyclic ring system unsubstituted or substituted with R5, unsubstituted or substituted with R6, and unsubstituted or substituted with —CH2NH2; and B is 1) a 5- or 6-membered monocyclic heterocycle having 1 or 2 heteroatoms independently selected from N, S or O, which is unsubstituted or substitut

Abstract: The present invention provides a compound of Formula (I) where A is a heterocycle ring system and B is a heterocycle ring system or aryl ring system, and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing thromboses, embolisms, hypercoagulability or fibrotic changes.

Abstract: The present invention provides a compound of Formula (I) where A is a heterocycle ring system and B is a heterocycle ring system or aryl ring system, and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing thromboses, embolisms, hypercoagulability or fibrotic changes.

Abstract: The present invention provides a compound of Formula (I) wherein R1, R2, R3 and R4 are independently H or C1-6 alkyl, provided that when R1, R2, and R3 are H, R4 is C1-6 alkyl, and when R1, R2, and R4 are H, R3 is C1-6 alkyl, and when R1, R3, and R4 are H, R2 is C1-6 alkyl, and when R2, R3, and R4 are H, R is C1-6 alkyl; and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing thromboses, embolisms, hypercoagulability or fibrotic changes.

Abstract: The present invention provides a compound of Formula (I) wherein R1 is H or C1-6 alkyl, R2, is H or C1-6 alkyl or CH2OH, R3 is H or C1-6 alkyl, and R4 is H or C1-6 alkyl, provided that when R1, R2, and R3 are H, R4 is C1-6 alkyl, and when R1, R2, and R4 are H, then R3 is C1-6 alkyl, and when R1, R3, and R4 are H, R2 is C1-6 alkyl or —CH2OH, and when R2, R3, and R4 are H, then R1 is C1-6 alkyl; A is 1) a 9-10 membered bicyclic heterocycle having 1-3 heteroatoms independently selected from N, S and O, which 9-10 membered bicyclic heterocycle is unsubstituted or substituted with R5 and unsubstituted or substituted with R6 and unsubstituted or substituted with NH2, or 2) a 6-9 membered monocyclic or bicyclic carbocyclic ring system unsubstituted or substituted with R5, unsubstituted or substituted with R6, and unsubstituted or substituted with —CH2NH2; and B is 1) a 5- or 6-membered monocyclic heterocycle having 1 or 2 heteroatoms independently selected from N, S or O, which is unsubstituted or substitut