Abstract: An implant insertion tool includes an outer shaft, an inner shaft received in the outer shaft, and two arms coupled to the outer shaft and the inner shaft. The inner shaft translates within the outer shaft and has angled ramps that slide within complementary angled ramps in the two arms. The arms engage an implant for insertion into a body. When the inner shaft translates along a longitudinal axis, it causes the angled ramps to slide against the complementary angled ramps in the arms such that the two arms move laterally relative to the longitudinal axis of the outer shaft to engage and disengage the implant.

Abstract: Described are coated particles containing a core and a coating, and pharmaceutical formulations containing these coated particles. The core contains a polymer or a hydrophobic drug. The coating contains a glycoprotein or a combination of a sugar and a protein. The coating surrounds the core. The coated particles are effectively absorbed by mucosa such as intestinal mucosa, GI tissue, and/or vaginal mucosa, and show increased systemic uptake following oral or mucosal administration. Optionally, the coated particles contain one or more active agents encapsulated in the core and/or embedded in the coating of the particles, for systemic or local delivery.

Abstract: A syngas generation system includes a molten carbonate fuel cell (MCFC) including a MCFC cathode configured to receive a MCFC cathode input stream including a flue gas stream and a MCFC anode configured to output a MCFC anode exhaust stream including carbon dioxide and steam. The syngas generation system further includes a solid oxide electrolysis cell (SOEC) including an SOEC cathode and an SOEC anode. The SOEC is configured to receive, at the SOEC cathode, an SOEC cathode input stream, the SOEC cathode input stream including at least a portion of the MCFC anode exhaust stream, co-electrolyze carbon dioxide and steam in the SOEC cathode input stream, and output, from the SOEC cathode, an SOEC cathode exhaust stream including carbon monoxide and hydrogen gas.

Abstract: A multi-axis robotic vial loading system designed for transporting containers. The multi-axis robotic loading system includes a conveyor belt for transporting vials to a multi-axis robotic arm. The multi-axis robotic arm includes a gripper configured to attach to one or more vials. The multi-axis robotic arm moves the vials from the conveyor belt to a storage container.

Abstract: Disclosed are compounds and pharmaceutically acceptable salts thereof that may be used in the treatment of subjects in need thereof. The compounds disclosed herein may be inhibitors of Ataxia-telangiectasia and RAD-3-related protein kinase (ATR). Also disclosed are pharmaceutical compositions containing the compounds or pharmaceutically acceptable salts thereof and methods of their preparation and use.

Abstract: An implant insertion tool includes an outer shaft, an inner shaft received in the outer shaft, and two arms coupled to the outer shaft and the inner shaft. The inner shaft translates within the outer shaft and has angled ramps that slide within complementary angled ramps in the two arms. The arms engage an implant for insertion into a body. When the inner shaft translates along a longitudinal axis, it causes the angled ramps to slide against the complementary angled ramps in the arms such that the two arms move laterally relative to the longitudinal axis of the outer shaft to engage and disengage the implant.

Abstract: Systems, methods, and non-transitory computer-readable media can generate individual feature data for each user of a plurality of users. A first cohort comprising a first plurality of users is generated, wherein the first plurality of users are selected from the plurality of users based on the individual feature data. A first set of cohort feature data associated with the first cohort is generated based on individual feature data for the first plurality of users. The first set of cohort feature data and a first set of cohort membership information are transmitted to a modeler. The first set of cohort membership information identifies each user of the plurality of users.

Abstract: A sleeping bag system has the appearance of a stuffed character when not in use as a sleeping bag and includes a torso including a torso compartment therein, a first limb having a first arm compartment therein which is in connection with the torso compartment, a second limb having a second arm compartment therein which is in connection with the torso compartment, at least a third limb having at least a first leg compartment therein which is in connection with the torso compartment. The sleeping bag system further includes an opening in the torso providing access to the torso compartment from outside of the sleeping bag system and an item removably storable in the torso compartment which is adapted to provide stability to the sleeping bag system such that the sleeping bag system can sit upright without support when not in use as a sleeping bag.

Abstract: The present invention provides a device and method for testing a material for the presence of DNA. The system includes a centrifuge, a microchip performing cell lysis and an enclosure that contains an isothermal ballast material and chromogenic agent that melts at a specific temperature and displays a color change, respectively.

Abstract: A system for resolving item-processing exceptions typically includes a processor, a memory, and an exception resolution module stored in the memory. The exception resolution module is typically configured for: receiving an item-processing exception; determining a source of the item-processing exception; based on the source of the item-processing exception, identifying a defined exception resolution process; based on the defined exception resolution process, creating and configuring a pipeline context for resolving the item-processing exception, the pipeline context including the defined exception resolution process; storing the pipeline context in a pipeline database; adding the pipeline context to a pipeline queue; selecting, via a pipeline manager service, the pipeline context from the pipeline queue; and executing, via a worker thread, the pipeline context by executing the defined exception resolution process.

Abstract: A sleeping bag system has the appearance of a stuffed character when not in use as a sleeping bag and includes a torso including a torso compartment therein, a first limb having a first arm compartment therein which is in connection with the torso compartment, a second limb having a second arm compartment therein which is in connection with the torso compartment, at least a third limb having at least a first leg compartment therein which is in connection with the torso compartment. The sleeping bag system further includes an opening in the torso providing access to the torso compartment from outside of the sleeping bag system and an item removably storable in the torso compartment which is adapted to provide stability to the sleeping bag system such that the sleeping bag system can sit upright without support when not in use as a sleeping bag.

Abstract: The present invention relates to novel polymorphic forms of 8-fluoro-2-{4-[(methylamino)methyl]phenyl}-1,3,4,5-tetrahydro-6H-azepino[5,4,3-cd]indol-6-one, and to processes for their preparation. Such polymorphic forms may be a component of a pharmaceutical composition and may be used to treat a mammalian disease condition mediated by poly(ADP-ribose) polymerase activity including the disease condition such as cancer.

Abstract: In the Internet field, interfaces which support social interaction are used by two or more people to share information and content. An example is a geolocation (map-type) interface (a web page for instance) which is relied upon by users to obtain travel routes, plan trips and find geolocation information, such as stores, restaurants and other places. Described here is a system for advertising whereby targeted advertisements are displayed to users of such an interface and the advertisements are the result of an analysis of user behavior during a particular interface session or several sessions, so advertisements are closely targeted to each particular user.

Abstract: The present invention relates to novel polymorphic forms of 8-fluoro-2-{4-[(methylamino)methyl]phenyl}-1,3,4,5-tetrahydro-6H-azepino[5,4,3-cd]indol-6-one, and to processes for their preparation. Such polymorphic forms may be a component of a pharmaceutical composition and may be used to treat a mammalian disease condition mediated by poly(ADP-ribose) polymerase activity including the disease condition such as cancer.

Abstract: Aspects of the disclosure relate generally to providing a user with an image navigation experience. For instance, a first image of a multidimensional space is provided with an overlay line indicating a direction in which the space extends into the first image such that a second image is connected to the first image along a direction of the overlay line. User input indicating a swipe across a portion of the display is received. When swipe occurred at least partially within an interaction zone defining an area around the overlay line at which the user can interact with the space, the swipe indicates a request to display an image different from the first image. The second image is selected and provided for display based on the swipe and a connection graph connecting the first image and the second image along the direction of the overlay line.

Abstract: A system for resolving item-processing exceptions typically includes a processor, a memory, and an exception resolution module stored in the memory. The exception resolution module is typically configured for: receiving an item-processing exception; determining a source of the item-processing exception; based on the source of the item-processing exception, identifying a defined exception resolution process; based on the defined exception resolution process, creating and configuring a pipeline context for resolving the item-processing exception, the pipeline context including the defined exception resolution process; storing the pipeline context in a pipeline database; adding the pipeline context to a pipeline queue; selecting, via a pipeline manager service, the pipeline context from the pipeline queue; and executing, via a worker thread, the pipeline context by executing the defined exception resolution process.

Abstract: Methods, systems, and computer program products for providing recommendations for an activity to a user are provided. In one method, the method tracks status information of a plurality of users, and detects a trigger for providing recommendations for an activity. In response the trigger, the method identifies a cluster of users based on the status information of the users. The method further retrieves profiles and behavioral characteristics of the users in the identified cluster, and provides one or more recommendations for the activity to the user based, at least in part, upon the behavioral characteristics and the profiles.

Abstract: A sleeping bag system has the appearance of a stuffed character when not in use as a sleeping bag and includes a torso including a torso compartment therein, a first limb having a first arm compartment therein which is in connection with the torso compartment, a second limb having a second arm compartment therein which is in connection with the torso compartment, at least a third limb having at least a first leg compartment therein which is in connection with the torso compartment. The sleeping bag system further includes an opening in the torso providing access to the torso compartment from outside of the sleeping bag system and an item removably storable in the torso compartment which is adapted to provide stability to the sleeping bag system such that the sleeping bag system can sit upright without support when not in use as a sleeping bag.

Abstract: The present invention relates to novel polymorphic forms of 8-fluoro-2-{4-[(methylamino)methyl]phenyl}-1,3,4,5-tetrahydro-6H-azepino[5,4,3-cd]indol-6-one, and to processes for their preparation. Such polymorphic forms may be a component of a pharmaceutical composition and may be used to treat a mammalian disease condition mediated by poly(ADP-ribose) polymerase activity including the disease condition such as cancer.

Abstract: In one aspect, computing device(s) may determine a plurality of fragments for a three-dimensional (3D) model of a geographical location. Each fragment of the plurality of fragments may correspond to a pixel of a blended image and each fragment has a fragment color from the 3D model. The one or more computing devices may determine geospatial location data for each fragment based at least in part on latitude information, longitude information, and altitude information associated with the 3D model. For each fragment of the plurality of fragments, the one or more computing devices may identify a pixel color and an image based at least in part on the geospatial location data, determine a blending ratio based on at least one of a position and an orientation of a virtual camera, and generate the blended image based on at least the blending ratio, the pixel color, and the fragment color.