Patents by Inventor Camilla M. Kao

Camilla M. Kao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polyketides and antibiotics produced by combinatorial techniques
    Patent number: 7741456
    Abstract: Combinatorial libraries of polyketides can be obtained by suitable manipulation of a host modular polyketide synthase gene cluster such as that which encodes the PKS for erythromycin. The combinatorial library is useful as a source of pharmaceutically active compounds. In addition, novel polyketides and antibiotics are prepared using this method.
    Type: Grant
    Filed: October 2, 2006
    Date of Patent: June 22, 2010
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Chaitan Khosla, Camilla M. Kao
  • Combinatorial polyketide libraries produced using a modular PKS gene cluster as scaffold
    Publication number: 20080200659
    Abstract: Combinatorial libraries of polyketides can be obtained by suitable manipulation of a host modular polyketide synthase gene cluster such as that which encodes the PKS for erythromycin. The combinatorial library is useful as a source of pharmaceutically active compounds. In addition, novel polyketides and antibiotics are prepared using this method.
    Type: Application
    Filed: October 2, 2006
    Publication date: August 21, 2008
    Applicant: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Chaitan Khosla, Camilla M. Kao
  • Recombinant production of novel polyketides
    Patent number: 7312048
    Abstract: Novel polyketides and novel methods of efficiently producing both new and known polyketides, using recombinant technology, are disclosed. In particular, a novel host-vector system is described which is used to produce polyketide synthases which in turn catalyze the production of a variety of polyketides.
    Type: Grant
    Filed: September 15, 2005
    Date of Patent: December 25, 2007
    Assignees: The Board of Trustees of the Leland Stanford University, The John Innes Institute
    Inventors: Chaitan Khosla, David A. Hopwood, Susanne Ebert-Khosla, Robert McDaniel, Hong Fu, Camilla M. Kao
  • Macrolide analogs
    Patent number: 6927057
    Abstract: Combinatorial libraries of polyketides can be obtained by suitable manipulation of a host modular polyketide synthase gene cluster such as that which encodes the PKS for erythromycin. The combinatorial library is useful as a source of pharmaceutically active compounds. In addition, novel polyketides and antibiotics are prepared using this method.
    Type: Grant
    Filed: May 16, 2001
    Date of Patent: August 9, 2005
    Assignees: Kosan Biosciences, The Board of Trustees of the Leland Stanford Junior University
    Inventors: Chaitan Khosla, Gary Ashley, Camilla M. Kao, Robert McDaniel
  • Combinatorial polyketide libraries produced using a modular PKS gene cluster as scaffold
    Publication number: 20030194785
    Abstract: Combinatorial libraries of polyketides can be obtained by suitable manipulation of a host modular polyketide synthase gene cluster such as that which encodes the PKS for erythromycin. The combinatorial library is useful as a source of pharmaceutically active compounds. In addition, novel polyketides and antibiotics are prepared using this method.
    Type: Application
    Filed: January 10, 2003
    Publication date: October 16, 2003
    Inventors: Chaitan Khosla, Gary Ashley, Hong Fu, Camilla M. Kao, Robert McDaniel
  • Combinatorial polyketide libraries produced using a modular PKS gene cluster as scaffold
    Publication number: 20030170725
    Abstract: Combinatorial libraries of polyketides can be obtained by suitable manipulation of a host modular polyketide synthase gene cluster such as that which encodes the PKS for erythromycin. The combinatorial library is useful as a source of pharmaceutically active compounds. In addition, novel polyketides and antibiotics are prepared using this method.
    Type: Application
    Filed: August 6, 2002
    Publication date: September 11, 2003
    Inventors: Chaitan Khosla, Camilla M. Kao
  • Combinatorial polyketide libraries produced using a modular PKS gene cluster as scaffold
    Patent number: 6558942
    Abstract: Combinatorial libraries of polyketides can be obtained by suitable manipulation of a host modular polyketide synthase gene cluster such as that which encodes the PKS for erythromycin. The combinatorial library is useful as a source of pharmaceutically active compounds. In addition, novel polyketides and antibiotics are prepared using this method.
    Type: Grant
    Filed: May 6, 1998
    Date of Patent: May 6, 2003
    Assignee: The Leland Stanford Junior University
    Inventors: Chaitan Khosla, Camilla M. Kao
  • Combinatorial polyketide libraries produced using a modular PKS gene cluster as scaffold
    Publication number: 20030077760
    Abstract: Combinatorial libraries of polyketides can be obtained by suitable manipulation of a host modular polyketide synthase gene cluster such as that which encodes the PKS for erythromycin. The combinatorial library is useful as a source of pharmaceutically active compounds.
    Type: Application
    Filed: March 12, 2002
    Publication date: April 24, 2003
    Inventors: Chaitan Khosla, Gary Ashley, Hong Fu, Camilla M. Kao, Robert McDaniel
  • Combinatorial polyketide libraries produced using a modular PKS gene cluster as scaffold
    Publication number: 20030077707
    Abstract: Combinatorial libraries of polyketides can be obtained by suitable manipulation of a host modular polyketide synthase gene cluster such as that which encodes the PKS for erythromycin. The combinatorial library is useful as a source of pharmaceutically active compounds.
    Type: Application
    Filed: March 12, 2002
    Publication date: April 24, 2003
    Inventors: Chaitan Khosla, Gary Ashley, Hong Fu, Camilla M. Kao, Robert McDaniel
  • Recombinant production of novel polyketides
    Publication number: 20030068677
    Abstract: Novel polyketides and novel methods of efficiently producing both new and known polyketides, using recombinant technology, are disclosed. In particular, a novel host-vector system is described which is used to produce polyketide synthases which in turn catalyze the production of a variety of polyketides.
    Type: Application
    Filed: March 12, 2002
    Publication date: April 10, 2003
    Inventors: Chaitan Khosla, Camilla M. Kao
  • Macrolide analogs
    Publication number: 20030040084
    Abstract: Combinatorial libraries of polyketides can be obtained by suitable manipulation of a host modular polyketide synthase gene cluster such as that which encodes the PKS for erythromycin. The combinatorial library is useful as a source of pharmaceutically active compounds. In addition, novel polyketides and antibiotics are prepared using this method.
    Type: Application
    Filed: May 9, 2001
    Publication date: February 27, 2003
    Inventors: Chaitan Khosla, Gary Ashley, Hong Fu, Camilla M. Kao, Robert McDaniel
  • Macrolide analogs
    Publication number: 20020068332
    Abstract: Combinatorial libraries of polyketides can be obtained by suitable manipulation of a host modular polyketide synthase gene cluster such as that which encodes the PKS for erythromycin. The combinatorial library is useful as a source of pharmaceutically active compounds. In addition, novel polyketides and antibiotics are prepared using this method.
    Type: Application
    Filed: May 16, 2001
    Publication date: June 6, 2002
    Inventors: Chaitan Khosla, Gary Ashley, Hong Fu, Camilla M. Kao, Robert McDaniel
  • Modified modular PKS with retained scaffold
    Patent number: 6391594
    Abstract: Combinatorial libraries of polyketides can be obtained by suitable manipulation of a host modular polyketide synthase gene cluster such as that which encodes the PKS for erythromycin. The combinatorial library is useful as a source of pharmaceutically active compounds.
    Type: Grant
    Filed: April 30, 1997
    Date of Patent: May 21, 2002
    Assignees: Kosan Biosciences, Inc., The Leland Stanford Junior University
    Inventors: Chaitan Khosla, Gary Ashley, Hong Fu, Camilla M. Kao, Robert McDaniel
  • MODIFIED MODULAR PKS WITH RETAINED SCAFFOLD
    Publication number: 20020034797
    Abstract: Combinatorial libraries of polyketides can be obtained by suitable manipulation of a host modular polyketide synthase gene cluster such as that which encodes the PKS for erythromycin. The combinatorial library is useful as a source of pharmaceutically active compounds.
    Type: Application
    Filed: April 30, 1997
    Publication date: March 21, 2002
    Inventors: CHAITAN KHOSLA, GARY ASHLEY, HONG FU, CAMILLA M. KAO, ROBERT MCDANIEL
  • Method to prepare macrolide analogs
    Publication number: 20010024810
    Abstract: Combinatorial libraries of polyketides can be obtained by suitable manipulation of a host modular polyketide synthase gene cluster such as that which encodes the PKS for erythromycin. The combinatorial library is useful as a source of pharmaceutically active compounds.
    Type: Application
    Filed: December 18, 2000
    Publication date: September 27, 2001
    Inventors: Chaitan Khosla, Gary Ashley, Hong Fu, Camilla M. Kao, Robert McDaniel