Patents by Inventor Camille Delon

Camille Delon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MODIFIED IL-18 POLYPEPTIDES
    Publication number: 20230357342
    Abstract: The present disclosure relates a modified interleukin 18 (IL-18) polypeptide, methods of making the same, and methods of using the modified IL-18 polypeptides for treatment of diseases including cancer. The modified IL-18 polypeptide can exhibit an ability to induce interferon gamma (IFN?) production when in contact with a cell, exhibit a diminished ability to be inhibited by IL-18 binding protein (IL-18BP) compared to wild type IL-18 (WT IL-18), and exhibit a ratio of half-maximal inhibitory concentration (IC50) by IL-18BP to half-maximal effective concentration (EC50) to induce IFN? production which is greater than that of WT IL-18.
    Type: Application
    Filed: February 23, 2023
    Publication date: November 9, 2023
    Inventors: Vijaya Raghavan PATTABIRAMAN, Bertolt KREFT, Arnaud GOEPFERT, Tiziano ONGARO, Jean-Philippe CARRALOT, Philipp MOOSMANN, Régis BOEHRINGER, Benoit HORNSPERGER, Roy MEODED, Kea MARTIN, Camille DELON, Andrew CHI
  • MONOCLONAL ANTIBODIES AGAINST BCMA
    Publication number: 20230322957
    Abstract: The invention relates to new antibodies against BCMA, their manufacture and use.
    Type: Application
    Filed: November 21, 2022
    Publication date: October 12, 2023
    Inventors: Minh Diem Vu, Klaus Strein, Oliver Ast, Marina Bacac, Camille Delon, Lydia Jasmin Hanisch, Anne Freimoser-Grundschober, Christian Klein, Ekkehard Moessner, Samuel Moser, Pablo Umana, Tina Weinzierl
  • Modified IL-2 polypeptides and uses thereof
    Patent number: 11633488
    Abstract: The present disclosure relates to modified IL-2 polypeptides, compositions comprising modified IL-2 polypeptides, methods of making the same, and methods of using the modified IL-2 polypeptides for treatment of diseases. In one aspect, the disclosure relates to the treatment of cancer using the modified IL-2 polypeptides. In some embodiments, the disclosed IL-2 polypeptides exhibit preferential binding characteristics to IL-2 receptor ?? complex (IL-2R?) over IL-2 receptor ??? complex (IL-2R?). In some embodiments, the molecular weight distribution of the modified IL-2 polypeptides is monodispersed.
    Type: Grant
    Filed: January 8, 2021
    Date of Patent: April 25, 2023
    Assignee: Bright Peak Therapeutics AG
    Inventors: Vijaya Raghavan Pattabiraman, Roberto Iacone, Jean-Philippe Carralot, Matilde Arévalo-Ruiz, Jeffrey William Bode, Alexander Mayweg, Fränzi Weibel, Anna Haydn, Régis Boehringer, Görkem Kurtuldu Sahin, Claudia Fetz, Camille Delon, Eric Armentani, Alexander Flohr, Giorgio Ottaviani
  • MODIFIED IL-18 POLYPEPTIDES AND USES THEREOF
    Publication number: 20220056091
    Abstract: The present disclosure relates to modified IL-18 polypeptides, compositions comprising modified IL-18 polypeptides, methods of making the same, and methods of using the modified IL-18 polypeptides for treatment of diseases. In one aspect, the disclosure relates to the treatment of cancer using the modified IL-18 polypeptides. In some embodiments, the disclosed IL-18 polypeptides induce the production of IFN?. In some embodiments, the disclosed IL-18 polypeptides induce the production of IFN? without being neutralized by IL-18 binding protein.
    Type: Application
    Filed: August 19, 2021
    Publication date: February 24, 2022
    Inventors: Vijaya Raghavan PATTABIRAMAN, Jean-Philippe CARRALOT, Bertolt KREFT, Jeffrey William BODE, Régis BOEHRINGER, Matilde ARÉVALO-RUIZ, Camille DELON, Amélie WIEDERKEHR, Claudia FETZ, Anna HAYDN, Alexander FLOHR, Roberto IACONE, Benoit HORNSPERGER, Chongqing WANG
  • MODIFIED IL-2 POLYPEPTIDES AND USES THEREOF
    Publication number: 20210252157
    Abstract: The present disclosure relates to modified IL-2 polypeptides, compositions comprising modified IL-2 polypeptides, methods of making the same, and methods of using the modified IL-2 polypeptides for treatment of diseases. In one aspect, the disclosure relates to the treatment of cancer using the modified IL-2 polypeptides. In some embodiments, the disclosed IL-2 polypeptides exhibit preferential binding characteristics to IL-2 receptor ?? complex (IL-2R?) over IL-2 receptor ??? complex (IL-2R?). In some embodiments, the molecular weight distribution of the modified IL-2 polypeptides is monodispersed.
    Type: Application
    Filed: January 8, 2021
    Publication date: August 19, 2021
    Inventors: Vijaya Raghavan PATTABIRAMAN, Roberto IACONE, Jean-Philippe CARRALOT, Matilde ARÉVALO-RUIZ, Jeffrey William BODE, Alexander MAYWEG, Fränzi WEIBEL, Anna HAYDN, Régis BOEHRINGER, Görkem KURTULDU SAHIN, Claudia FETZ, Camille DELON, Eric ARMENTANI, Alexander FLOHR, Giorgio OTTAVIANI
  • MONOCLONAL ANTIBODIES AGAINST BCMA
    Publication number: 20200283545
    Abstract: The invention relates to new antibodies against BCMA, their manufacture and use.
    Type: Application
    Filed: March 17, 2020
    Publication date: September 10, 2020
    Inventors: Minh Diem Vu, Klaus Strein, Oliver Ast, Marina Bacac, Camille Delon, Lydia Jasmin Hanisch, Anne Freimoser-Grundschober, Christian Klein, Ekkehard Moessner, Samuel Moser, Pablo Umana, Tina Weinzierl
  • Monoclonal antibodies against BCMA
    Patent number: 10683369
    Abstract: The invention relates to new antibodies against BCMA, their manufacture and use.
    Type: Grant
    Filed: August 3, 2016
    Date of Patent: June 16, 2020
    Assignee: EngMab Sàrl
    Inventors: Minh Diem Vu, Klaus Strein, Oliver Ast, Marina Bacac, Camille Delon, Lydia Jasmin Hanisch, Anne Freimoser-Grundschober, Christian Klein, Ekkehard Moessner, Samuel Moser, Pablo Umana, Tina Weinzierl
  • MONOCLONAL ANTIBODIES AGAINST BCMA
    Publication number: 20190352427
    Abstract: The invention relates to new antibodies against BCMA, their manufacture and use.
    Type: Application
    Filed: August 3, 2016
    Publication date: November 21, 2019
    Inventors: Minh Diem Vu, Klaus Strein, Oliver Ast, Marina Bacac, Camille Delon, Lydia Jasmin Duerner, Anne Freimoser-Grundschober, Christian Klein, Ekkehard Moessner, Samuel Moser, Pablo Umana, Tina Weinzierl