Abstract: The erythromycin salt of 5-(3-carboxy-1-oxopropoxy)-.alpha.,.alpha., 4-trimethyl-3-cyclohesene-1-methanol acid is described.This salt shows a mucosecretolytic and fluidizing activity. There is further described a process for the preparation of said salt, as well as pharmaceutical compositions with mucosecretolytic and fluidizing action which contain the novel salt.

Abstract: A novel ester of (+) 6-methoxy-.alpha.-methyl-2-naphthalene acetic acid is described.Such ester is obtained by reaction of the (+)6-methoxy-.alpha.-methyl-2-naphthalene acetic acid chloride as prepared by a well known technique, with (-).alpha..sup.4, .alpha..sup.4 -dimethyl-1-cyclohexane-1,4-dimethanol.There are further described pharmaceutic compositions having mucosecretolytic, anti-inflammatory analgesic and antipyretic activity, which contain the novel ester.

Abstract: The use of highly pure sobrerol-d,1 as a balsamic and a respiratory analeptic.

Abstract: A novel derivative of (-)-6,6-dimethylbicyclo[3.3.1]ept-2-ene-2-methanol is disclosed.The compound which is an object of the present invention, is the derivative :.alpha.,.alpha.-dimethyl-5-hydroxy-3-cyclohexene-1,4-dimethanol.The present invention further discloses the process for obtaining the compound which consists in preparing the (-)-6,6-dimethylbicyclo[3.3.1]ept-2-ene-2-methanol epoxide, thereafter hydrating the above compound and separating the compound from the hydration products. Finally, this invention comprises the pharmaceutical compositions containing the compound which possess a pharmacological mucosecretolytic activity.

Abstract: The object of the present invention are the following diastereoisomer compounds (as derived from (-)-5-(1-hydroxy-1-methylethyl)-2-methyl-2-cyclohexene-1-one):(I): (1S-5R) 5-hydroxy-.alpha.,.alpha.-4,5-tetramethyl-3-cyclohexene-1-methanol (CO/1516)(II): (1S-5S) 5-hydroxy-.alpha.,.alpha.-4,5-tetramethyl-3-cyclohexene-1-methanol (CO/1517)which can be separated from the mixture of (I)+(II) at the % proportion of 44.44/55.55; said mixture will be hereinafter also designated either by the code CO/1483 or by (III).This invention provides, furthermore, the process for obtaining the mixture (III) (CO/1483) by reaction of (-)-5-(1-hydroxy-1-methylethyl)-2-methyl-2-cyclohexene-1-one with methyl-lithium and for separating the diastereoisomers (I) and (II) by a chromatographic method.Finally, the present invention comprises pharmaceutical compositions which contain the compounds (I), (II) and the mixture (III), when possess a pharmacologic mucosecretolytic activity.

Abstract: New piperazine derivatives and homologs thereof of formula ##STR1## wherein n is equal to 2 or 3 and m to 1, 2 or 3;X represents hydrogen or a methyl group;R represents hydrogen or a C.sub.1 to C.sub.6 lower alkyl group or a C.sub.1 to C.sub.3 hydroxyalkyl group; andR.sub.1 is a cyclohexyl group of formula ##STR2## wherein R.sub.2 is hydrogen or a C.sub.1 to C.sub.6 lower alkyl group. The compounds have antiulcer and antisecretory activity.

Abstract: New piperazine derivatives and homologs thereof of formula ##STR1## wherein n is equal to 2 or 3 and m to 1, 2 or 3; X REPRESENTS HYDROGEN OR A METHYL GROUPR represents hydrogen or a C.sub.1 to C.sub.6 lower alkyl group or a C.sub.1 to C.sub.3 hydroxyalkyl group; andR.sub.1 is one of the following groups:A substituted cyclohexyl of formula ##STR2## wherein R.sub.2 is hydrogen or a C.sub.1 to C.sub.6 lower alkyl group, A SUBSTITUTED PHENYL OF FORMULA ##STR3## wheein R.sub.3 is hydrogen, methyl or ethyl, OR WHEREIN R.sub.1 is norbornyl, bornyl or cinnamyl, are useful as antiulcerous compounds.

Abstract: A process for the industrial production of terpene nitrolaminic derivatives, comprising a first step wherein the terpene nitroso-chlorides are prepared reacting in a concentrated organic acid medium, selected from formic acid or acetic acid, terpenic materials, selected from alpha-pinene, limonene, alpha-terpineol and the like, with concentrated hydrochloric acid, in the presence of compounds having the formula R--OH, wherein R is an alkyl group, having 1 to 7 carbon atoms, and of alkali nitrites; and a second step wherein the nitroso-chlorides, thus precipitated, are reacted after purification and recrystallization, with an aminic derivative, selected from ammonia, amines, amino-alcohols and amino-acids, in an organic solvent medium in a ratio of nitroso-chloride to aminic derivative of 1 : 1, at a temperature ranging between 50.degree. and 70.degree.