Abstract: Some disclosed examples pertain to an apparatus that can include a platen, a light source system, a receiver system, and an electromagnetic interference (EMI) shield. The light source system can include light source system circuitry, a light-emitting component, and a light guide component having a substantially uniform cross-section. The light-emitting component provides light to an area of the platen via the light guide component. The receiver system can include at least two receiver stack portions residing proximate on either side of the light guide component. The receiver system detects acoustic waves corresponding to a photoacoustic response of a target object proximate the area of the platen, to light emitted by the light source system. The EMI shield shields the receiver system from at least some of the EMI produced by the light source system circuitry. The light guide component conveys light through a portion of the EMI shield.

Abstract: Some disclosed examples involve controlling a light-steering system to direct light emitted by at least a first light source of a light source system to a first plurality of areas of a target object, wherein controlling the light-steering system involves controlling one or more adjustable micromirrors, one or more adjustable lenses, one or more adjustable diffraction gratings, or combinations thereof. Some examples involve receiving ultrasonic receiver signals from an ultrasonic receiver system corresponding to photoacoustic responses of the target object to light provided the light source system to each area of the first plurality of areas and determining a selected area of the target object from which additional ultrasonic receiver signals will be obtained, wherein determining the selected area involves detecting a blood vessel within the target object. Some examples involve controlling the light source system to obtain additional ultrasonic receiver signals from the selected area.

Abstract: Some disclosed examples involve receiving ultrasonic receiver signals from an ultrasonic receiver system corresponding to ultrasonic waves generated by a target object responsive to light from a light source system, estimating one or more blood vessel features based, at least in part, on the ultrasonic receiver signals and estimating blood pressure based, at least in part, on the one or more blood vessel features. Some disclosed examples involve receiving inertial sensor data from an inertial sensor system, determining whether the inertial sensor data indicates apparatus motion that exceeds a threshold and controlling a photoacoustic plethysmography (PAPG) system that includes the light source system and the ultrasonic receiver system according to whether the apparatus motion exceeds the threshold.

Abstract: Described herein are shock wave devices and methods for the treatment of calcified heart valves. One variation of a shock wave device may comprise an elongated flexible tube carried by a sheath. The tube may have a fluid input end, which may be located near a proximal end of the sheath. The tube may include a loop portion. The loop portion may be configured to be at least partially accommodated within a cusp of the heart valve. The tube may be fillable with a conductive fluid. In some variations, the shock wave device may include an array of electrode pairs associated with a plurality of wires positioned within the loop portion of a tube. The electrode pairs may be electrically connectable to a voltage source and configured to generate shock waves in the conductive fluid in response to voltage pulses.

Abstract: The invention provides a system for treating an occlusion within a body lumen. The system may comprise an insulated outer sheath; an elongated conductive tube, wherein the insulated outer sheath is circumferentially mounted around the elongated conductive tube; and an insulated wire having a helically coiled portion at a distal end of the insulated wire. The coiled portion includes an exposed distal tip, and a distal portion of the elongated conductive tube is circumferentially mounted around the distal coiled portion of the insulated wire. When a voltage is applied across the insulated wire and the elongated conductive tube, a current is configured to flow from the exposed distal tip of the insulated wire to the elongated conductive tube to generate a plurality of cavitation bubbles. In an alternate embodiment, an elongated central electrode is used in place of the conductive tube.

Abstract: Some disclosed examples involve controlling, by a control system, a light source system to provide light to a target object on an outer surface of a platen and receiving, by the control system, ultrasonic receiver signals from each of a plurality of ultrasonic receiver elements in an array of ultrasonic receiver elements. The ultrasonic receiver signals may correspond to ultrasonic waves generated by the target object responsive to the light from the light source system. Some disclosed examples involve applying, by the control system, a receiver-side beamforming process to the ultrasonic receiver signals, to produce a beamformed ultrasonic receiver image and detecting, by the control system, a blood vessel within the targe object based, at least in part, on the beamformed ultrasonic receiver image.

Abstract: Described herein are shock wave devices and methods for the treatment of calcified heart valves. One variation of a shock wave device may comprise an elongated flexible tube carried by a sheath. The tube may have a fluid input end, which may be located near a proximal end of the sheath. The tube may include a loop portion. The loop portion may be configured to be at least partially accommodated within a cusp of the heart valve. The tube may be fillable with a conductive fluid. In some variations, the shock wave device may include an array of electrode pairs associated with a plurality of wires positioned within the loop portion of a tube. The electrode pairs may be electrically connectable to a voltage source and configured to generate shock waves in the conductive fluid in response to voltage pulses.

Abstract: The invention provides a system for treating an occlusion within a body lumen. The system may comprise an insulated outer sheath; an elongated conductive tube, wherein the insulated outer sheath is circumferentially mounted around the elongated conductive tube; and an insulated wire having a helically coiled portion at a distal end of the insulated wire. The coiled portion includes an exposed distal tip, and a distal portion of the elongated conductive tube is circumferentially mounted around the distal coiled portion of the insulated wire. When a voltage is applied across the insulated wire and the elongated conductive tube, a current is configured to flow from the exposed distal tip of the insulated wire to the elongated conductive tube to generate a plurality of cavitation bubbles. In an alternate embodiment, an elongated central electrode is used in place of the conductive tube.

Abstract: As disclosed herein, a computer-implemented method is provided. In one aspect, the computer-implemented method may include receiving, from a client device, images of a user. The computer-implemented method may include determining a target appearance of an avatar of the user. The computer-implemented method may include generating, based on the images and the target appearance, renders of the avatar. The computer-implemented method may include determining, based on a difference between first and second renders, a first adjustment to a weight associated with a first parameter for generating the renders and a second adjustment to a weight associated with a second parameter for generating the renders. The computer-implemented method may include generating, based on the adjustments, a third render of the avatar, the third render appearing more similar to the target appearance relative to the first render and the second render. A system and a non-transitory computer-readable storage medium are also disclosed.

Abstract: An apparatus may include a platen, a light source system and an ultrasonic receiver system. The platen may be configured to separate one or more received arterial ultrasonic waves generated by blood in an artery, by an arterial wall, or by a combination thereof, from one or more other types of received ultrasonic waves. The platen may have an outer surface with an acoustic impedance that is configured to approximate the acoustic impedance of human skin. The outer surface of the platen may be configured to conform to a surface of the human skin. The apparatus may include a noise reduction system. The light source system may include at least one multi-junction laser diode. The apparatus may include a mirror layer residing between the ultrasonic receiver system and the platen.

Abstract: An apparatus may include a platen, a light source system and an ultrasonic receiver system. The platen may be configured to separate one or more received arterial ultrasonic waves generated by blood in an artery, by an arterial wall, or by a combination thereof, from one or more other types of received ultrasonic waves. The platen may have an outer surface with an acoustic impedance that is configured to approximate the acoustic impedance of human skin. The outer surface of the platen may be configured to conform to a surface of the human skin. The apparatus may include a noise reduction system. The light source system may include at least one multi-junction laser diode. The apparatus may include a mirror layer residing between the ultrasonic receiver system and the platen.

Abstract: An apparatus may include a platen, a light source system and an ultrasonic receiver system. The light source system may be configured to provide light to a target object on an outer surface of the platen. The light source system may be configured to direct the light along a first axis oriented at a first angle relative to the outer surface of the platen. The ultrasonic receiver system may be configured to receive ultrasonic waves generated by the target object responsive to the light from the light source system. The ultrasonic receiver system may include one or more receiver elements residing in a receiver plane. A normal to the receiver plane being may be oriented along a second axis at a second angle relative to the outer surface of the platen. The first angle may be different from the second angle.

Abstract: An apparatus may include a platen, a light source system and a receiver system. The light source system may at least a first light-emitting component and at least a first light guide component. The first light guide component may be configured to transmit light from the first light-emitting component towards a target object in contact with a first area of the platen. The receiver system may include at least two receiver stack portions. A first receiver stack portion may reside proximate a first side of a first portion of the first light guide component and a second receiver stack portion may reside proximate a second side of the first portion of the first light guide component. The receiver system may be configured to detect acoustic waves corresponding to a photoacoustic response of the target object to light emitted by the light source system.

Abstract: An apparatus may include a platen, a light source system and an ultrasonic receiver system. The platen may be configured to separate one or more received arterial ultrasonic waves generated by blood in an artery, by an arterial wall, or by a combination thereof, from one or more other types of received ultrasonic waves. The platen may have an outer surface with an acoustic impedance that is configured to approximate the acoustic impedance of human skin. The outer surface of the platen may be configured to conform to a surface of the human skin. The apparatus may include a noise reduction system. The light source system may include at least one multi-junction laser diode. The apparatus may include a mirror layer residing between the ultrasonic receiver system and the platen.

Abstract: An apparatus may include a platen, a light source system and an ultrasonic receiver system. The platen may be configured to separate one or more received arterial ultrasonic waves generated by blood in an artery, by an arterial wall, or by a combination thereof, from one or more other types of received ultrasonic waves. The platen may have an outer surface with an acoustic impedance that is configured to approximate the acoustic impedance of human skin. The outer surface of the platen may be configured to conform to a surface of the human skin. The apparatus may include a noise reduction system. The light source system may include at least one multi-junction laser diode. The apparatus may include a mirror layer residing between the ultrasonic receiver system and the platen.

Abstract: An apparatus may include a platen, a light source system and an ultrasonic receiver system. The platen may be configured to separate one or more received arterial ultrasonic waves generated by blood in an artery, by an arterial wall, or by a combination thereof, from one or more other types of received ultrasonic waves. The platen may have an outer surface with an acoustic impedance that is configured to approximate the acoustic impedance of human skin. The outer surface of the platen may be configured to conform to a surface of the human skin. The apparatus may include a noise reduction system. The light source system may include at least one multi-junction laser diode. The apparatus may include a mirror layer residing between the ultrasonic receiver system and the platen.

Abstract: An apparatus may include a substrate, a light source system and a receiver system. The light source system may be configured to emit light through an area of the substrate, from a first side of the substrate towards a target object in contact with a second and opposite side of the substrate. The receiver system may include one or more receivers residing in, on or proximate the substrate. The receiver system may be configured to detect surface acoustic waves propagating in the substrate corresponding to a photoacoustic response of the target object to light emitted by the light source system. In some examples, the apparatus may include a control system. The control system may be configured to receive surface acoustic wave signals from the receiver system corresponding to detected surface acoustic waves and to detect at least one structure within the target object based on the surface acoustic wave signals.

Abstract: The invention provides a system for treating an occlusion within a body lumen. The system may comprise an insulated outer sheath; an elongated conductive tube, wherein the insulated outer sheath is circumferentially mounted around the elongated conductive tube; and an insulated wire having a helically coiled portion at a distal end of the insulated wire. The coiled portion includes an exposed distal tip, and a distal portion of the elongated conductive tube is circumferentially mounted around the distal coiled portion of the insulated wire. When a voltage is applied across the insulated wire and the elongated conductive tube, a current is configured to flow from the exposed distal tip of the insulated wire to the elongated conductive tube to generate a plurality of cavitation bubbles. In an alternate embodiment, an elongated central electrode is used in place of the conductive tube.

Abstract: The invention provides a system for treating an occlusion within a body lumen. The system may comprise an insulated outer sheath; an elongated conductive tube, wherein the insulated outer sheath is circumferentially mounted around the elongated conductive tube; and an insulated wire having a helically coiled portion at a distal end of the insulated wire. The coiled portion includes an exposed distal tip, and a distal portion of the elongated conductive tube is circumferentially mounted around the distal coiled portion of the insulated wire. When a voltage is applied across the insulated wire and the elongated conductive tube, a current is configured to flow from the exposed distal tip of the insulated wire to the elongated conductive tube to generate a plurality of cavitation bubbles. In an alternate embodiment, an elongated central electrode is used in place of the conductive tube.

Abstract: Described herein are shock wave devices and methods for the treatment of calcified heart valves. One variation of a shock wave device may comprise an elongated flexible tube carried by a sheath. The tube may have a fluid input end, which may be located near a proximal end of the sheath. The tube may include a loop portion. The loop portion may be configured to be at least partially accommodated within a cusp of the heart valve. The tube may be fillable with a conductive fluid. In some variations, the shock wave device may include an array of electrode pairs associated with a plurality of wires positioned within the loop portion of a tube. The electrode pairs may be electrically connectable to a voltage source and configured to generate shock waves in the conductive fluid in response to voltage pulses.