Abstract: The present invention relates to a rock physico-mechanical testing chamber and a three-dimensional multi-field information perception cabin in simulated environments of deep earth, deep space, and deep sea. The testing chamber comprises a cabin body and 6 butting indenters; the 6 butting indenters are pairwise located in an X-axis direction, a Y-axis direction and a Z-axis direction; the 6 butting indenters are respectively mounted in through holes on six faces of the cabin body, inner ends of the butting indenters extend into the cabin body, outer ends of the butting indenters are exposed out of the cabin body, and the butting indenters can axially move relative to the cabin body. The present application can be used to achieve the reservoir rock mechanical behavior testing in real time under high and low environments.

Abstract: The present invention relates to a deep rock in situ environment reconstruction and integrated three-dimensional mechanical-thermo-acousto-seismic-flow testing method, which comprises: preparing a cubic sample; placing the cubic sample in a sample holder; extending the 6 indenters to butt with the sample holder; butting 6 butting indenters with the 6 indenters; butting each of 6 hydraulic actuators with one of the butting indenters, performing stress loading on the cubic sample by the hydraulic actuator, filling a fluid medium into the cubic sample by a percolation medium channel, and dynamically measuring related parameters. The present application can achieve three-way multi-parameter synchronous monitoring and acquisition of deformation, acoustic emission, ultrasonic wave, temperature field, percolation field and heat flow field.

Abstract: The present invention relates to a rock physico-mechanical testing chamber and a three-dimensional multi-field information perception cabin in simulated environments of deep earth, deep space, and deep sea. The testing chamber comprises a cabin body and 6 butting indenters; the 6 butting indenters are pairwise located in an X-axis direction, a Y-axis direction and a Z-axis direction; the 6 butting indenters are respectively mounted in through holes on six faces of the cabin body, inner ends of the butting indenters extend into the cabin body, outer ends of the butting indenters are exposed out of the cabin body, and the butting indenters can axially move relative to the cabin body. The present application can be used to achieve the reservoir rock mechanical behavior testing in real time under high and low environments.

Abstract: The present invention relates to a deep rock in situ environment reconstruction and integrated three-dimensional mechanical-thermo-acousto-seismic-flow testing method, which comprises: preparing a cubic sample; placing the cubic sample in a sample holder; extending the 6 indenters to butt with the sample holder; butting 6 butting indenters with the 6 indenters; butting each of 6 hydraulic actuators with one of the butting indenters, performing stress loading on the cubic sample by the hydraulic actuator, filling a fluid medium into the cubic sample by a percolation medium channel, and dynamically measuring related parameters. The present application can achieve three-way multi-parameter synchronous monitoring and acquisition of deformation, acoustic emission, ultrasonic wave, temperature field, percolation field and heat flow field.

Abstract: The application relates to a rock physico-mechanical testing system in simulated environments of deep earth, deep space, and deep sea, which comprises a three-axis six-direction loading system and an experimental cabin, wherein the three-axis six-direction loading system comprises a loading frame and 6 actuators; an experimental cabin accommodation chamber is arranged in the loading frame, the experimental cabin accommodation chamber is provided with 6 loading ports, and six actuators are each adapted to one of the loading ports; the experimental cabin comprises a cabin body and 6 butting indenters, wherein the 6 butting indenters are respectively arranged in through holes of the cabin body in six directions and can axially move relative to the cabin body; and front ends of the six actuators are each operatively butted with a rear end of one of the butting indenters. The application can be used to achieve the reservoir rock mechanical behavior testing.

Abstract: The present invention relates to a use of CBX4 as a target for activation of HIV-1 latent infection. The present invention found by research that, inhibiting CBX4 causes a good ability for activation of HIV-1 latent, a knockdown of CBX4 can effectively promote a transcription of LTR of HIV-1; and afterwards the present invention has found that, by the knockdown of CBX4 in a J-lat 10.6 cell model of HIV-1 latent infection, GFP gene expression is up-regulated, and HIV-1 can be effectively activated. An overexpression of the CBX4 protein in TZM-bl cells can effectively decrease a transcriptional activity of LTR of HIV-1. It is found by further detection that, decreased expression of CBX4 protein will reduce a degree of enrichment of H3K9 trimethylation and H3K27 trimethylation of LTR of HIV-1, thereby activating HIV-1 latent infection.