Patents by Inventor Candice C. Askwith

Candice C. Askwith has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Peptide potentiation of acid-sensory ion channel in pain
    Publication number: 20040132637
    Abstract: An assay for determining agonists, antagonists, or modulators for acid-sensing ion channels. The assay is especially useful for screening analgesics. The screening assay can be provided in a kit form. The assay comprises administering the composition to be screened to cells expressing acid-gated channels and then determining whether the composition inhibits, enhances, or has no effect on the channels when acid is introduced. The determination can be performed by analyzing whether a current is sustained by the cells in the presence of the composition and the acid. This current can be compared to that sustained by the FMRFamide and related peptides.
    Type: Application
    Filed: August 18, 2003
    Publication date: July 8, 2004
    Applicant: University of Iowa Research Foundation
    Inventors: Michael J. Welsh, Candice C. Askwith
  • Peptide potentiation of acid-sensory ion channel in pain
    Patent number: 6635432
    Abstract: An assay for determining agonists, antagonists, or modulators for acid-sensing ion channels. The assay is especially useful for screening analgesics. The screening assay can be provided in a kit form. The assay comprises administering the composition to be screened to cells expressing acid-gated channels and then determining whether the composition inhibits, enhances, or has no effect on the channels when acid is introduced. The determination can be performed by analyzing whether a current is sustained by the cells in the presence of the composition and the acid. This current can be compared to that sustained by the FMRFamide and related peptides.
    Type: Grant
    Filed: April 25, 2000
    Date of Patent: October 21, 2003
    Assignee: University of Iowa Research Foundation
    Inventors: Michael J. Welsh, Candice C. Askwith