Abstract: The present invention provides a conjugate and preparation method thereof, a pharmaceutical composition comprising the conjugate and use of the pharmaceutical composition in the manufacture of a medicament for the treatment or prevention of a disease.

Abstract: The present invention provides a conjugate and preparation method thereof, a pharmaceutical composition comprising the conjugate and use of the pharmaceutical composition in the manufacture of a medicament for the treatment or prevention of a disease.

Abstract: The present application provides a true three-dimensional dynamic and static combination shear device under high-temperature, high pore pressure and chemical coupling and a method therefor, specifically designed for the rock indoor loading test technical field. The device includes a hydraulic system, a pore pressure coupling system, an annular frame, a frame base, a lateral horizontal support platform, a lateral floating frame, a normal dynamic and static combination loading cylinder, a lateral dynamic and static combination loading cylinder, a tangential hydrostatic loading cylinder, a tangential disturbance loading cylinder, a high-temperature box, and a true three-dimensional high-temperature, high pore pressure and chemical coupling shear box.

Abstract: A conjugate and preparation method therefor, comprising a medication composition comprising the conjugate and a use of the medication composition in preparing medications for the treatment or prevention of diseases.

Abstract: The present invention provides a conjugate and preparation method thereof, a pharmaceutical composition comprising the conjugate and use of the pharmaceutical composition in the manufacture of a medicament for the treatment or prevention of a disease.

Abstract: A power amplifier has an input terminal for receiving a signal to be amplified and an output terminal to which the amplified signal is passed, and comprises single stage which-, or a plurality of cascaded amplifier stages one of, which-, is formed from a plurality of amplifiers connected in parallel with their input ports interconnected and their output ports interconnected. Said one stage may be the last stage. In one arrangement said one stage comprises two or more amplifiers at least one of which is biased at class AB and at least another of which is biased at class C. Alternatively said one stage comprises two or more amplifiers at least one of which is biased at class AB and at least another of which may be switchably biased at class AB or class C. Again, alternatively, the said one stage may comprise two or more amplifiers, each of which may be switchably biased at class AB or class C and the gates widths of which may be different.