Patents by Inventor Cao Xie

Cao Xie has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • VAP polypeptide and use thereof in preparation of drug for targeted diagnosis and treatment of tumor
    Patent number: 11622990
    Abstract: Provided in the present invention are highly stable D-configuration polypeptides DVAP and SVAP having a high binding activity to the GRP78 protein, and also provided are an L-configuration polypeptide LVAP and a DVAP-or SVAP-modified model drug and a macromolecule carrier material, and the use thereof in the construction of a tumour image and a drug-delivery system for targeted treatment.
    Type: Grant
    Filed: December 6, 2017
    Date of Patent: April 11, 2023
    Assignee: FUDAN UNIVERSITY
    Inventors: Weiyue Lu, Danni Ran, Jiani Mao, Cao Xie
  • Method for preparing biofilm-coated drug nanocrystal and application thereof
    Patent number: 11260032
    Abstract: A nano drug delivery system includes a biofilm-coated drug nanocrystal. A drug in a physical form of nanocrystal is directly used as a rigid supporting skeleton, and is filled in a biofilm. The nano drug delivery system has the advantages of high drug loading capacity, good biocompatibility, long systemic circulation time and drug sustained release.
    Type: Grant
    Filed: March 30, 2018
    Date of Patent: March 1, 2022
    Assignee: Shanghai Whittlong Pharmaceutical Institute
    Inventors: Weiyue Lu, Zhilan Chai, Xuefeng Hu, Cao Xie, Huimin Hou, Hao Wang
  • METHOD FOR PREPARING BIOFILM-COATED DRUG NANOCRYSTAL AND USE THEREOF
    Publication number: 20200069601
    Abstract: A nano drug delivery system includes a biofilm-coated drug nanocrystal. A drug in a physical form of nanocrystal is directly used as a rigid supporting skeleton, and is filled in a biofilm. The nano drug delivery system has the advantages of high drug loading capacity, good biocompatibility, long systemic circulation time and drug sustained release.
    Type: Application
    Filed: March 30, 2018
    Publication date: March 5, 2020
    Applicant: Shanghai Whittlong Pharmaceutical Institute
    Inventors: Weiyue LU, Zhilan CHAI, Xuefeng HU, Cao XIE, Huimin HOU, Hao WANG
  • VAP POLYPEPTIDE AND USE THEREOF IN PREPARATION OF DRUG FOR TARGETED DIAGNOSIS AND TREATMENT OF TUMOR
    Publication number: 20190314446
    Abstract: Provided in the present invention are highly stable D-configuration polypeptides DVAP and SVAP having a high binding activity to the GRP78 protein, and also provided are an L-configuration polypeptide LVAP and a DVAP-or SVAP-modified model drug and a macromolecule carrier material, and the use thereof in the construction of a tumour image and a drug-delivery system for targeted treatment.
    Type: Application
    Filed: December 6, 2017
    Publication date: October 17, 2019
    Inventors: Weiyue Lu, Danni Ran, Jiani Mao, Cao Xie