Abstract: Provided are antibody-cytokine fusion proteins comprising an anti-PD-L1 antibody and an Interleukin 21, and methods for preparing the same, as well as applications of the fusion proteins for therapeutic purpose.

Abstract: A method for multiple-round driver selection performed by a computing system, the method including receiving a service request from a user device; identifying a plurality of driver candidates based in part on the service request, such that each of the plurality of driver candidates has driver data; for each of the plurality of driver candidates, generating a score based on the driver data; grouping the plurality of driver candidates into a plurality of candidate groups based in part on the score of each of the plurality of driver candidates; iteratively transmitting a job request to each candidate group of the plurality of candidate groups until one or more job acceptance is received in response to the job request, such that the job request is transmitted to all drivers in each candidate group; selecting one of the one or more job acceptances; and assigning the service request to the driver associated with the selected one of the one or more job acceptances.

Abstract: An improved, high-quality Thai text-to-phoneme converter. Syllabification is performed strictly according to the Thai pronunciation rules. Initial vowels, Thai syllable structures, special vowels, leading vowels, syllables with silent marks, unterminated vowels and terminated vowels are used to accurately implement the Thai syllabification. After syllabification, the most probable phonemes are obtained for all of the syllables using a rule-based approach in one embodiment of the invention.