Patents by Inventor Carey Lynn Horchler

Carey Lynn Horchler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Azetidine derivatives for tau imaging
    Patent number: 10301308
    Abstract: The present invention provides a novel compound of the formula: methods of making this compound, methods of using this compound for tau imaging, and preparations of tau imaging formulations.
    Type: Grant
    Filed: November 4, 2016
    Date of Patent: May 28, 2019
    Assignee: Eli Lilly and Company
    Inventors: Giorgio Attardo, Carey Lynn Horchler, Shyamali Ghosh, Hui Xiong
  • AZETIDINE DERIVATIVES FOR TAU IMAGING
    Publication number: 20180282322
    Abstract: The present invention provides a novel compound of the formula: methods of making this compound, methods of using this compound for tau imaging, and preparations of tau imaging formulations.
    Type: Application
    Filed: November 4, 2016
    Publication date: October 4, 2018
    Inventors: Giorgio Attardo, Carey Lynn Horchler, Shyamali Ghosh, Hui Xiong
  • 1,2,5,10-tetrahydropyridazino[4,5-b]quinoline-1,10-diones and their use for the treatment of pain
    Patent number: 6946463
    Abstract: Compounds according to structural diagram (I) are disclosed, wherein R1, A, E and D are as defined in the specification. Also disclosed are pharmaceutical compositions comprising a pain-ameliorating effective amount of a compound in accord with structural diagram (I). The following is an examiner's statement of reasons for allowance: In view of applicants' amendments to the claims which limit “E” to phenyl or cycloalkyl groups the rejections of the previous action no longer pertain as they at best teach “E” as alkyl.
    Type: Grant
    Filed: September 28, 2001
    Date of Patent: September 20, 2005
    Assignee: Astrazeneca AB
    Inventors: Dean Gordon Brown, Rebecca Ann Urbanek, Megan Murphy, Wenhua Xiao, Frances Marie McLaren, Edward Vacek, Thomas Bare, Carey Lynn Horchler, Christine Barlaam, Gary Banks Steelman
  • 7-chloro-4-hydroxy-2-(2-pyridylethyl)-1,2,5,10-tetrahydropyridazino[4,5-b]quinoline-1,10-dione and the use thereof for the treatment of pain
    Patent number: 6933297
    Abstract: A compound, 7-chloro-4-hydroxy-2-(2-pyridylethyl)-1,2,5,10-tetrahydropyridazino[4,5-b]quinoline-1,10-dione, its (?) enantiomer, its (+) enantiomer, pharmaceutically-acceptable salts thereof, a method for treating pain comprising administering a pain-ameliorating effective amount of the (?) enantiomer to an individual suffering from pain and pharmaceutical compositions containing the (?) enantiomer are disclosed.
    Type: Grant
    Filed: September 28, 2001
    Date of Patent: August 23, 2005
    Assignee: AstraZeneca AB
    Inventors: Dean Gordon Brown, Rebecca Ann Urbanek, Megan Murphy, Wenhua Xiao, Frances Marie McLaren, Edward Vacek, Thomas Bare, Carey Lynn Horchler, Christine Barlaam, Gary Banks Steelman, Vernon Alford
  • 1, 2, 5, 10-tetrahydropyridazino[4, 5-b]quinoline-1,10-diones and their use for the treatment of pain
    Patent number: 6833368
    Abstract: Compounds useful for the treatment of pain in accord with structural diagram (I), or tautomers or pharmaceutically-acceptable salts of such compounds, wherein R1 and A are as disclosed in the specification. Also disclosed are methods for the treatment of pain using compounds according to structural diagram (I) and pharmaceutical compositions comprising compounds according to structural diagram (I).
    Type: Grant
    Filed: October 9, 2003
    Date of Patent: December 21, 2004
    Assignee: AstraZeneca AB
    Inventors: Megan Murphy, Wenhua Xiao, Dean Gordon Brown, Rebecca Ann Urbanek, Frances Marie McLaren, Edward Vacek, Thomas Bare, Carey Lynn Horchler, Christine Barlaam, Gary Banks Steelman, Vernon Alford
  • 1, 2, 5, 10-tetrahydropyridazino[4, 5-b]quinoline-1,10-diones and their use for the treatment of pain
    Publication number: 20040058927
    Abstract: Compounds useful for the treatment of pain in accord with structural diagram (I), or tautomers or pharmaceutically-acceptable salts of such compounds, wherein R1 and A are as disclosed in the specification. Also disclosed are methods for the treatment of pain using compounds according to structural diagram (I) and pharmaceutical compositions comprising compounds according to structural diagram (I).
    Type: Application
    Filed: October 9, 2003
    Publication date: March 25, 2004
    Inventors: Megan Murphy, Wenhua Xiao, Dean Gordon Brown, Rebecca Ann Urbanek, Frances Marie McLaren, Edward Vacek, Thomas Bare, Carey Lynn Horchler, Christine Barlaam, Gary Banks Steelman, Vernon Alford
  • 7-Chloro-4-hydroxy-2-(2-pyridylethyl)-1,2,5,10-tetrahydropyridazino[4,5-b]quinoline-1,10-dione and the use thereof for the treatment of pain
    Publication number: 20040053930
    Abstract: A compound, 7-chloro-4-hydroxy-2-(2-pyridylethyl)-1,2,5,10-tetrahydropyridazino[4,5-b] quinoline-1,10-dione, its (−) enantiomer, its (+) enantiomer, pharmaceutically-acceptable salts thereof, a method for treating pain comprising administering a pain-ameliorating effective amount of the (−) enantiomer to an individual suffering from pain and pharmaceutical compositions containing the (−) enantiomer are disclosed.
    Type: Application
    Filed: September 8, 2003
    Publication date: March 18, 2004
    Inventors: Dean Gordon Brown, Rebecca Ann Urbanek, Megan Murphy, Wenhua Xiao, Frances Marie Mclaren, Edward Vacek, Thomas Bare, Carey Lynn Horchler, Christine Barlaam, Gary Banks Steelman, Vernon Alford
  • 1, 2, 5, 10-tetrahydropyridazino[4,5-b]quinoline-1,10-diones and their use for the treatment of pain
    Publication number: 20040053929
    Abstract: Compounds according to structural diagram (I) are disclosed, wherein R1, A, E and D are as defined in the specification. Also disclosed are pharmaceutical compositions comprising a pain-ameliorating effective amount of a compound in accord with structural diagram (I).
    Type: Application
    Filed: September 8, 2003
    Publication date: March 18, 2004
    Inventors: Dean Gordon Brown, Rebecca Ann Urbanek, Megan Murphy, Wenhua Xiao, Frances Marie Mclaren, Edward Vacek, Thomas Bare, Carey Lynn Horchler, Christine Barlaam, Gary Banks Steelman
  • Methods and compositions for the treatment of pain
    Publication number: 20030181449
    Abstract: A method for the treatment of pain is disclosed comprising administration of a pain-ameliorating effective amount of any compound according to structural diagram I; 1
    Type: Application
    Filed: February 24, 2003
    Publication date: September 25, 2003
    Inventors: Rebecca Ann Urbanek, Thomas Michael Bare, Dean Gordon Brown, Wenhua Xiao, Gary Banks Steelman, Megan Murphy, Carey Lynn Horchler
  • Method and composition for the treatment of pain
    Publication number: 20030153571
    Abstract: A method for the treatment of pain is disclosed comprising administration of a pain-ameliorating effective amount of any compound according to structural diagram I; 1
    Type: Application
    Filed: December 17, 2002
    Publication date: August 14, 2003
    Inventors: Dean Gordon Brown, Thomas Michael Bare, Megan Murphy, Rebecca Ann Urbanek, Wenhua Xiao, Marie Frances McLaren, Carey Lynn Horchler