Abstract: Systems and methods are provided for assessing nasal deviation and symmetry via the processing of facial surface data. Facial surface data may be processed to determine a nasal deviation measure indicative of a lateral deviation between a nasal midline and a facial midplane. The facial surface data may also be processed to determine a measure of nasal symmetry associated with a selected nasal surface region, such as an aesthetic subunit. Nasal deviation and symmetry information based on both measures may then be presented. In some example implementations, a single nasal symmetry measure is generated and present for a given nasal surface region. Reference surface data characterizing a reference symmetrical facial shape and having a defined facial direction relative to a coordinate system may be employed to align the facial surface data prior to the determination of the nasal deviation and nasal symmetry measures.

Abstract: A positioning and alignment instrument, and methods of use thereof, are provided for facilitating the alignment and insertion of a device, such as a guide wire, into bone. The instrument includes a handheld anchoring component and a rotatable guidance component. During use, the anchoring component is anchored into bone via anchoring protrusions, such that the position and orientation of the anchoring component is fixed relative to the bone. The guidance component, which is mechanically supported by the anchoring component, includes a device guide channel for receiving the device and guiding the device towards an insertion location adjacent to the distal end of the anchoring component. The guidance component is rotatable relative to the anchoring component about a rotation axis that is located adjacent to the distal end of the anchoring component, such that the insertion location remains adjacent to the distal end of the anchoring component under rotation.

Abstract: The present disclosure discloses a bone stabilization device (also referred to as a bone tape), which includes a composite flexible construct including a rigidifiable biocompatible sheet structure having first and second opposed surfaces. A biocompatible cement is located on the first surface. In use the composite flexible construct is applied to a bone with the cement contacted directly to the bone. The cement is made of a material that, once adhered to the bone, is curable to mechanically and/or ionically bond to the sheet structure and to chemically bond to the bone to achieve a permanent bond. The bone tape allows simultaneous alignment and stabilization of multiple articulated fragments for successful 3D reconstruction of shattered bones. Initial flexibility and translucency provided by the bone tape can facilitate the temporary stabilization and alignment adjustment of multiple fragments, prior to permanent rigid bonding.

Abstract: A positioning and alignment instrument, and methods of use thereof, are provided for facilitating the alignment and insertion of a device, such as a guide wire, into bone. The instrument includes a handheld anchoring component and a rotatable guidance component. During use, the anchoring component is anchored into bone via anchoring protrusions, such that the position and orientation of the anchoring component is fixed relative to the bone. The guidance component, which is mechanically supported by the anchoring component, includes a device guide channel for receiving the device and guiding the device towards an insertion location adjacent to the distal end of the anchoring component. The guidance component is rotatable relative to the anchoring component about a rotation axis that is located adjacent to the distal end of the anchoring component, such that the insertion location remains adjacent to the distal end of the anchoring component under rotation.

Abstract: The present disclosure discloses a bone stabilization device (also referred to as a bone tape), which includes a composite flexible construct including a rigidifiable biocompatible sheet structure having first and second opposed surfaces. A biocompatible cement is located on the first surface. In use the composite flexible construct is applied to a bone with the cement contacted directly to the bone. The cement is made of a material that, once adhered to the bone, is curable to mechanically and/or ionically bond to the sheet structure and to chemically bond to the bone to achieve a permanent bond. The bone tape allows simultaneous alignment and stabilization of multiple articulated fragments for successful 3D reconstruction of shattered bones. Initial flexibility and translucency provided by the bone tape can facilitate the temporary stabilization and alignment adjustment of multiple fragments, prior to permanent rigid bonding.

Abstract: The present application provides miniature and micro-scale conformable chain mail devices for skeletal fixation, stabilization, and repair, and methods of manufacture and use thereof. The structural devices comprise a conformable sheet of interconnecting polygonal links that form a chain mail mesh having a first and a second outer surface, wherein: the interconnecting links comprise planar surfaces that combine to form the first and second outer surfaces, respectively, of the conformable sheet. Also provide are methods of using the structural device for stabilization of bone tissue, for fixation of bone tissue, as a bone graft patch or as a thin bone tissue replacement.

Abstract: The present disclosure discloses a bone stabilization device (also referred to as a bone tape), which includes a composite flexible construct including a rigidifiable biocompatible sheet structure having first and second opposed surfaces. A biocompatible cement is located on the first surface. In use the composite flexible construct is applied to a bone with the cement contacted directly to the bone. The cement is made of a material that, once adhered to the bone, is curable to mechanically and/or ionically bond to the sheet structure and to chemically bond to the bone to achieve a permanent bond. The bone tape allows simultaneous alignment and stabilization of multiple articulated fragments for successful 3D reconstruction of shattered bones. Initial flexibility and translucency provided by the bone tape can facilitate the temporary stabilization and alignment adjustment of multiple fragments, prior to permanent rigid bonding.

Abstract: The present disclosure discloses a bone stabilization device (also referred to as a bone tape), which includes a composite flexible construct including a rigidifiable biocompatible sheet structure having first and second opposed surfaces. A biocompatible cement is located on the first surface. In use the composite flexible construct is applied to a bone with the cement contacted directly to the bone. The cement is made of a material that, once adhered to the bone, is curable to mechanically and/or ionically bond to the sheet structure and to chemically bond to the bone to achieve a permanent bond. The bone tape allows simultaneous alignment and stabilization of multiple articulated fragments for successful 3D reconstruction of shattered bones. Initial flexibility and translucency provided by the bone tape can facilitate the temporary stabilization and alignment adjustment of multiple fragments, prior to permanent rigid bonding.

Abstract: Various embodiments are described herein for a coil electrode, RF applicator and RF treatment apparatus, along with an associated method of operation, that have been developed for treating tumors in bone tissue, including large tumors with a single treatment session or ablating intravertebral nerves. Embodiments are also described that provide the capability to perform multifocal treatments for safe and effective treatment of multiple bone tumors or ablating intravertebral nerves. Embodiments are also described that provide a 3-tiered multi-modality treatment regimen which would sequentially include RF ablation of a bone tumor, tumor debulking and vertebroplasty or ablating intravertebral nerves as part of pain treatment.

Abstract: A fixation device is provided to immobilize a spinal motion segment and promote posterior fusion, used as stand-alone instrumentation or as an adjunct to an anterior approach. The device functions as a multi-level fusion system including modular single-level implementations. At a single-level the implant includes a pair of plates spanning two adjacent vertebrae with embedding teeth on the medially oriented surfaces directed into the spinous processes or laminae. The complementary plates at a single-level are connected via a cross-post passed through the interspinous process gap The freedom of rotational motion of both the cross-post and collar enables the complementary plates to be connected at a range of angles in the axial and coronal planes accommodating varying morphologies of the posterior elements in the cervical, thoracic and lumbar spine. To achieve multi-level fusion the single-level implementation can be connected in series using an interlocking mechanism fixed by a set-screw.

Abstract: A fixation device to immobilize a spinal motion segment and promote posterior fusion, used as stand-alone instrumentation or as an adjunct to an anterior approach. The device functions as a multi-level fusion system including modular single-level implementations. At a single-level the implant includes a pair of plates spanning two adjacent vertebrae with embedding teeth on the medially oriented surfaces directed into the spinous processes or laminae. The complementary plates at a single-level are connected via a cross-post with a hemi-spherical base and cylindrical shaft passed through the interspinous process gap and ratcheted into an expandable collar. The expandable collar's spherical profile contained within the opposing plate allows for the ratcheting mechanism to be correctly engaged creating a uni-directional lock securing the implant to the spine when a medially directed force is applied to both complementary plates using a specially designed compression tool.