Abstract: A cartridge to be used for adsorption dialysis. A container having flexible walls are arranged to provide an inner space enclosing adsorption powder, comprising activated carbon, a phosphate adsorbent and a potassium ion adsorbent and other adsorbents. A sufficient amount of activated carbon is provided for adsorption of urea by the activated carbon. The cartridge forms a vacuum-packed transportation cartridge by generating a sub-pressure in the inner space, whereby the powder particles are immobilized and the cartridge becomes stiff. Before use, the cartridge is primed by introducing a liquid into the inner space, which introduction takes place at a low pressure. During use, dialysis solution is circulated through the cartridge, which is still exposed to a sub-pressure, whereby the flexible walls are sucked against the powder material.

Abstract: A cartridge to be used for adsorption dialysis. A container having flexible walls are arranged to provide an inner space enclosing adsorption powder, comprising activated carbon, a phosphate adsorbent and a potassium ion adsorbent and other adsorbents. A sufficient amount of activated carbon is provided for adsorption of urea by the activated carbon. The cartridge forms a vacuum-packed transportation cartridge by generating a sub-pressure in the inner space, whereby the powder particles are immobilized and the cartridge becomes stiff. Before use, the cartridge is primed by introducing a liquid into the inner space, which introduction takes place at a low pressure. During use, dialysis solution is circulated through the cartridge, which is still exposed to a sub-pressure, whereby the flexible walls are sucked against the powder material.

Abstract: A method of producing a copper-chitosan polymer material for adsorption of urea from a dialysis solution. A solid chitosan polymer material is immersed in a copper salt solution of a weak acid, such as copper acetate, for allowing the copper ions to complex with the chitosan polymer. The macroporous chitosan polymer membrane has a thickness of no more than about 200 ??? and has a pore size of between about 1 to 100 ???, for example 20 to 50 ???. Alternatively, solid chitosan fibers, solid chitosan particles or a chitosan gel bead can be complexed with copper acetate. The concentration of the copper acetate solution is above 50 mM whereby gel formation of the solid chitosan material is avoided during the complexation step.

Abstract: A regeneration circuit for regeneration of a dialysis fluid. An inlet and an outlet are arranged to pass a dialysis fluid to and from the regeneration circuit by means of a pump. An adsorbent cartridge is arranged downstream of the pump and comprises an adsorbent made of e.g. activated carbon and an adsorbent made of metal-complexed chitosan and possibly further adsorbents. Downstream of the last adsorbent is arranged a further general adsorbent arranged to adsorb metal ions, such as copper ions, possibly given off by previous adsorbents. Such a general adsorbent is an adsorbent made of uncomplexed chitosan, which adsorb metal ions and does not adsorb physiological electrolytes commonly included in a dialysis fluid, such as sodium, potassium, calcium and magnesium ions.

Abstract: Claims 1-5 relate to methods for treatment of the human or animal body by therapy, since the claims describe changing the compositions of the circulation dialysis fluid, which will affect the ion concentration in the patient's blood. See PCT rule 43bis.1 (b) and PCT rule 67.1.(iv). Nevertheless, an examination has been conducted for these claims. The examination has been made in respect of the technical content of the claims.