Patents by Inventor Carina Holkenbrink

Carina Holkenbrink has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR PRODUCTION OF MOTH PHEROMONES IN YEAST
    Publication number: 20240076329
    Abstract: The present disclosure relates to methods for production of (Z)-11-hexadecen-1-ol in a yeast cell. Also disclosed are methods for production of (Z)-11-hexadecenal in a yeast cell. Also disclosed are methods for production of (Z)-11-hexadecen-1-yl acetate in a yeast cell. The disclosure also provides for nucleic acid constructs and yeast cells useful for performing the present methods, as well as to pheromone compositions.
    Type: Application
    Filed: May 8, 2023
    Publication date: March 7, 2024
    Inventors: Irina Borodina, Carina Holkenbrink, Marie Inger Dam, Christer Löfstedt, Baojian Ding, Hong-Lei Wang
  • METHODS AND CELL FACTORIES FOR PRODUCING INSECT PHEROMONES
    Publication number: 20230332096
    Abstract: The present invention relates to pheromone production, desaturated fatty alcohols or aldehydes or acetates using recombinant yeasts expressing acyl-CoA oxidase to shorten fatty acyl-CoA by two carbons, deleting endogenous acyl-CoA oxidase, express desaturase to introduce at least one double bond, acyl-CoA-reductase to convert fatty acyl-CoA into fatty alcohol. Further, acetyltransferase can be used to convert to desaturated acyl fatty acetate, alcohol dehydrogenase or fatty acyl oxidase to convert to desaturated fatty aldehyde.
    Type: Application
    Filed: February 10, 2020
    Publication date: October 19, 2023
    Applicant: BioPhero ApS
    Inventors: Irina Borodina, Leonie Wenning, Carina Holkenbrink, Kanchana Rueksomtawin Kildegaard, Baojian Ding, Christer Löfstedt, Karolis Petkevicius
  • Method for production of moth pheromones in yeast
    Patent number: 11685768
    Abstract: The present disclosure relates to methods for production of (Z)-11-hexadecen-1-ol in a yeast cell using desaturases and fatty acyl-CoA reductase. Also disclosed are methods for production of (Z)-11-hexadecenal in a yeast cell. Also disclosed are methods for production of (Z)-11-hexadecen-1-yl acetate in a yeast cell. The disclosure also provides for nucleic acid constructs and yeast cells useful for performing the present methods, as well as to pheromone compositions.
    Type: Grant
    Filed: June 24, 2016
    Date of Patent: June 27, 2023
    Assignee: Danmarks Tekniske Universitet
    Inventors: Irina Borodina, Carina Holkenbrink, Marie Inger Dam, Christer Löfstedt, Baojian Ding, Hong-Lei Wang
  • Production of desaturated fatty alcohols and desaturated fatty acyl acetates in yeast
    Publication number: 20230135852
    Abstract: The present invention relates to the production of compounds comprised in pheromones, in particular moth pheromones, such as desaturated fatty alcohols and desaturated fatty acyl acetates and derivatives thereof, from a yeast cell.
    Type: Application
    Filed: July 26, 2022
    Publication date: May 4, 2023
    Inventors: Irina Borodina, Carina Holkenbrink, Marie lnger Dam, Christer Löfstedt, Baojian Ding, Hong-Lei Wang
  • Production of desaturated fatty alcohols and desaturated fatty alcohol acetates in yeast
    Patent number: 11434506
    Abstract: The present invention relates to the production of compounds comprised in pheromones, in particular moth pheromones, such as desaturated fatty alcohols and desaturated fatty alcohol acetates and derivatives thereof, from a yeast cell.
    Type: Grant
    Filed: December 15, 2017
    Date of Patent: September 6, 2022
    Assignee: Danmarks Tekniske Universitet
    Inventors: Irina Borodina, Carina Holkenbrink, Marie Inger Dam, Christer Löfstedt, Baojian Ding, Hong-Lei Wang
  • Methods for producing fatty alcohols and derivatives thereof in yeast
    Patent number: 11345922
    Abstract: The present invention relates to oleaginous yeast cells for the production of fatty alcohols and derivatives thereof, in particular desaturated fatty alcohols, desaturated fatty acyl acetates and desaturated fatty aldehydes. Also provided are methods for obtaining such compounds, which are useful in pheromone compositions.
    Type: Grant
    Filed: December 15, 2017
    Date of Patent: May 31, 2022
    Assignee: Danmarks Tekniske Universitet
    Inventors: Irina Borodina, Carina Holkenbrink, Marie Inger Dam, Christer Löfstedt
  • PRODUCTION OF DESATURATED FATTY ALCOHOLS AND DESATURATED FATTY ACYL ACETATES IN YEAST
    Publication number: 20200102582
    Abstract: The present invention relates to the production of compounds comprised in pheromones, in particular moth pheromones, such as desaturated fatty alcohols and desaturated fatty acyl acetates and derivatives thereof, from a yeast cell.
    Type: Application
    Filed: December 15, 2017
    Publication date: April 2, 2020
    Applicant: Danmarks Tekniske Universitet
    Inventors: Irina Borodina, Carina Holkenbrink, Marie Inger Dam, Christer Löfstedt, Baojian Ding, Hong-Lei Wang
  • METHODS FOR PRODUCING FATTY ALCOHOLS AND DERIVATIVES THEREOF IN YEAST
    Publication number: 20190330646
    Abstract: The present invention relates to oleaginous yeast cells for the production of fatty alcohols and derivatives thereof, in particular desaturated fatty alcohols, desaturated fatty acyl acetates and desaturated fatty aldehydes. Also provided are methods for obtaining such compounds, which are useful in pheromone compositions.
    Type: Application
    Filed: December 15, 2017
    Publication date: October 31, 2019
    Inventors: Irina Borodina, Carina Holkenbrink, Marie Inger Dam, Christer Löfstedt
  • METHOD FOR PRODUCTION OF MOTH PHEROMONES IN YEAST
    Publication number: 20180162916
    Abstract: The present disclosure relates to methods for production of (Z)-11-hexadecen-1-ol in a yeast cell using desaturases and fatty acyl-CoA reductase. Also disclosed are methods for production of (Z)-11-hexadecenal in a yeast cell. Also disclosed are methods for production of (Z)-11-hexadecen-1-yl acetate in a yeast cell. The disclosure also provides for nucleic acid constructs and yeast cells useful for performing the present methods, as well as to pheromone compositions.
    Type: Application
    Filed: June 24, 2016
    Publication date: June 14, 2018
    Inventors: Irina Borodina, Carina Holkenbrink, Marie Inger Dam, Christer Löfstedt, Baojian Ding, Hong-Lei Wang