Patents by Inventor Carina I. Jette

Carina I. Jette has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GEM-DISUBSTITUTED PYRROLIDINES, PIPERAZINES, AND DIAZEPANES, AND COMPOSITIONS AND METHODS OF MAKING THE SAME
    Publication number: 20220213081
    Abstract: Described here are transition metal-catalyzed enantioselective arylation and vinylation reactions of ?-substituted lactams, such as ?-lactams. The use of various electrophiles and ligands are described, and result in the construction of ?-quaternary centers in good yields (up to 91% yield) and high enantioselectivities (up to 97% ee).
    Type: Application
    Filed: December 31, 2021
    Publication date: July 7, 2022
    Inventors: Brian M. Stoltz, Alexander W. Sun, Stephan N. Hess, Carina I. Jette, Irina Geibel, Shoshana Bachman, Masaki Hayashi, Hideki Shimizu, Jeremy B. Morgan, Shunya Sakurai, Zachary P. Sercel
  • GEM-DISUBSTITUTED PYRROLIDINES, PIPERAZINES, AND DIAZEPANES, AND COMPOSITIONS AND METHODS OF MAKING THE SAME
    Publication number: 20220119377
    Abstract: Described here are transition metal-catalyzed enantioselective arylation and vinylation reactions of ?-substituted lactams, such as ?-lactams. The use of various electrophiles and ligands are described, and result in the construction of ?-quaternary centers in good yields (up to 91% yield) and high enantioselectivities (up to 97% ee).
    Type: Application
    Filed: December 31, 2021
    Publication date: April 21, 2022
    Inventors: Brian M. Stoltz, Alexander W. Sun, Stephan N. Hess, Carina I. Jette, Irina Geibel, Shoshana Bachman, Masaki Hayashi, Hideki Shimizu, Jeremy B. Morgan, Shunya Sakurai, Zachary P. Sercel
  • Gem-disubstituted pyrrolidines, piperazines, and diazepanes, and compositions and methods of making the same
    Patent number: 11214568
    Abstract: Described here are transition metal-catalyzed enantioselective arylation and vinylation reactions of ?-substituted lactams, such as ?-lactams. The use of various electrophiles and ligands are described, and result in the construction of ?-quaternary centers in good yields (up to 91% yield) and high enantioselectivities (up to 97% ee).
    Type: Grant
    Filed: October 18, 2019
    Date of Patent: January 4, 2022
    Assignee: California Institute of Technology
    Inventors: Brian M. Stoltz, Alexander W. Sun, Stephan N. Hess, Carina I. Jette, Irina Geibel, Shoshana Bachman, Masaki Hayashi, Hideki Shimizu, Jeremy B. Morgan, Shunya Sakurai, Zachary P. Sercel
  • Methods for enantioselective allylic alkylation of esters, lactones, and lactams with unactivated allylic alcohols
    Patent number: 10745354
    Abstract: The present disclosure provides methods for enantioselective synthesis of cyclic and acyclic ?-quaternary carboxylic acid derivatives via nickel-catalyzed allylic alkylation.
    Type: Grant
    Filed: July 15, 2019
    Date of Patent: August 18, 2020
    Assignee: California Institute of Technology
    Inventors: Brian M. Stoltz, Aurapat Ngamnithiporn, Carina I. Jette, Shoshana Bachman, Scott C. Virgil, Sebastian Lackner
  • GEM-DISUBSTITUTED PYRROLIDINES, PIPERAZINES, AND DIAZEPANES, AND COMPOSITIONS AND METHODS OF MAKING THE SAME
    Publication number: 20200199114
    Abstract: Described here are transition metal-catalyzed enantioselective arylation and vinylation reactions of ?-substituted lactams, such as ?-lactams. The use of various electrophiles and ligands are described, and result in the construction of ?-quaternary centers in good yields (up to 91% yield) and high enantioselectivities (up to 97% ee).
    Type: Application
    Filed: October 18, 2019
    Publication date: June 25, 2020
    Inventors: Brian M. Stoltz, Alexander W. Sun, Stephan N. Hess, Carina I. Jette, Irina Geibel, Shoshana Bachman, Masaki Hayashi, Hideki Shimizu, Jeremy B. Morgan, Shunya Sakurai, Zachary P. Sercel
  • METHODS FOR ENANTIOSELECTIVE ALLYLIC ALKYLATION OF ESTERS, LACTONES, AND LACTAMS WITH UNACTIVATED ALLYLIC ALCOHOLS
    Publication number: 20200048201
    Abstract: The present disclosure provides methods for enantioselective synthesis of cyclic and acyclic ?-quaternary carboxylic acid derivatives via nickel-catalyzed allylic alkylation.
    Type: Application
    Filed: July 15, 2019
    Publication date: February 13, 2020
    Inventors: Brian M. Stoltz, Aurapat Ngamnithiporn, Carina I. Jette, Shoshana Bachman, Scott C. Virgil, Sebastian Lackner
  • Methods for enantioselective allylic alkylation of esters, lactones, and lactams with unactivated allylic alcohols
    Patent number: 10358422
    Abstract: The present disclosure provides methods for enantioselective synthesis of cyclic and acyclic ?-quaternary carboxylic acid derivatives via nickel-catalyzed allylic alkylation.
    Type: Grant
    Filed: November 1, 2018
    Date of Patent: July 23, 2019
    Assignee: California Institute of Technology
    Inventors: Brian M. Stoltz, Aurapat Ngamnithiporn, Carina I. Jette, Shoshana Bachman, Scott C. Virgil, Sebastian Lackner
  • METHODS FOR ENANTIOSELECTIVE ALLYLIC ALKYLATION OF ESTERS, LACTONES, AND LACTAMS WITH UNACTIVATED ALLYLIC ALCOHOLS
    Publication number: 20190135754
    Abstract: The present disclosure provides methods for enantioselective synthesis of cyclic and acyclic ?-quaternary carboxylic acid derivatives via nickel-catalyzed allylic alkylation.
    Type: Application
    Filed: November 1, 2018
    Publication date: May 9, 2019
    Inventors: Brian M. Stoltz, Aurapat Ngamnithiporn, Carina I. Jette, Shoshana Bachman, Scott C. Virgil, Sebastian Lackner