Patents by Inventor Carina Tan

Carina Tan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Rhesus monkey, dog and ferret melanin-concentrating hormone type 2 receptor
    Patent number: 7208282
    Abstract: The present invention identifies the presence of MCH-2R in the dog, ferret and rhesus monkey. MCH-2R is a G-protein coupled receptor that responds to MCH and is distinct from MCH-1R. MCH-2R polypeptide and nucleic acid sequences related to the dog, ferret, and rhesus monkey MCH-2R are described herein along with uses of such polypeptides and nucleic acids.
    Type: Grant
    Filed: May 28, 2002
    Date of Patent: April 24, 2007
    Assignees: Merck & Co., Inc., Banyu Pharmaceutical Co., Ltd.
    Inventors: Carina Tan, Hideki Sano
  • Cloning and identification of the motilin receptor
    Patent number: 7179886
    Abstract: The motilin receptor has been isolated and cloned, and nucleic acid sequences are given. Two spice variants have been identified. Also, assays for motilin receptor ligands are given. The identification of the cloned motilin receptor may be used to screen and identify compounds which bind to the receptor for use in a variety of gastric conditions, including gastric motility disorders.
    Type: Grant
    Filed: June 8, 1999
    Date of Patent: February 20, 2007
    Assignee: Merck & Co., Inc.
    Inventors: Scott D. Feighner, Arthur A. Patchett, Carina Tan, Karen Kulju McKee, Douglas MacNeil, Andrew D. Howard, Sheng-Shung Pong, Roy G. Smith
  • Rhesus monkey bombesin receptor subtype-3 (brs-3), nucleotides encoding same, and uses thereof
    Publication number: 20070037219
    Abstract: A rhesus monkey bombesin receptor subtype-3 has been isolated, cloned and sequenced. This receptor is characteristic of the G-protein family of receptors. Isolated rhesus monkey bombesin receptor subtype-3 may be used to screen and identify novel bombesin receptor modulators that may contribute to the regulation of endocrine processes, metabolism, or the cell cycle. Such compounds may be used in the treatment of conditions that result from deregulated expression of bombesin receptor subtype-3.
    Type: Application
    Filed: April 14, 2004
    Publication date: February 15, 2007
    Inventors: Carina Tan, Andrew Howard, Hideki Sano
  • Dog melanin-concentrating hormone receptor
    Patent number: 7148026
    Abstract: The present invention features polypeptides and nucleic acids related to a dog MCH receptor and uses of such polypeptides and nucleic acids. The dog MCH receptor is a G protein coupled receptor whose activity is stimulated by MCH binding.
    Type: Grant
    Filed: July 17, 2001
    Date of Patent: December 12, 2006
    Assignee: Merck & Co., Inc.
    Inventor: Carina Tan
  • Rhesus monkey, dog and feeret melanin-concentrating hormone type 1 receptor
    Publication number: 20040248129
    Abstract: The present invention features polypeptide and nucleic acid sequences related to the dog, ferret and rhesus monkey MCH-1R. Preferred polypeptides and nucleic acid contain a region common to the dog, ferret and rhesus monkey MCH-1R, which is not present in the human, rat, or mouse MCH-1R.
    Type: Application
    Filed: March 5, 2004
    Publication date: December 9, 2004
    Inventors: Carina Tan, Andreas W. Sailer, Jie Pan, Hideki Sano
  • Rhesus monkey, dog and ferret melanin-concentrating hormone type 2 receptor
    Publication number: 20040132045
    Abstract: The present invention identifies the presence of MCH-2R in the dog, ferret and rhesus monkey. MCH-2R is a G-protein coupled receptor that responds to MCH and is distinct from MCH-1R. MCH-2R polypeptide and nucleic acid sequences related to the dog, ferret, and rhesus monkey MCH-2R are described herein along with uses of such polypeptides and nucleic acids.
    Type: Application
    Filed: November 20, 2003
    Publication date: July 8, 2004
    Inventors: Carina Tan, Hideki Sano
  • Cell lines expressing a mch receptor
    Publication number: 20040072287
    Abstract: The present invention features neuroblastoma and skin cell carcinoma cell lines functionally expressing MCHR1 and the use of such cells to measure MCHR1 activity. Functional expression is preferably achieved in a neuroblastoma or skin cell carcinoma using a recombinant gene expressing MCHR1. The presence of a recombinant MCHR1 gene increases the level of MCHR1 expression facilitating the production and detection of MCHR1 activity.
    Type: Application
    Filed: August 25, 2003
    Publication date: April 15, 2004
    Inventors: Carina Tan, Margarita Nossoughi, Shigeru Tokita
  • Dog melanin-concentrating hormone receptor
    Publication number: 20030212252
    Abstract: The present invention features polypeptides and nucleic acids related to a dog MCH receptor and uses of such polypeptides and nucleic acids. The dog MCH receptor is a G protein coupled receptor whose activity is stimulated by MCH binding.
    Type: Application
    Filed: January 17, 2003
    Publication date: November 13, 2003
    Inventor: Carina Tan
  • Galanin receptor (GALR2) binding assay
    Patent number: 6544753
    Abstract: A new galanin receptor, GALR2, is described. Also provided are nucleic acids encoding same and various assays to identify ligands particular to said receptor. Ligands so identified are useful for the treatment of obesity, treatment of pain, and treatment of cognitive disorders.
    Type: Grant
    Filed: June 26, 2000
    Date of Patent: April 8, 2003
    Assignee: Merck & Co., Inc.
    Inventors: Carina Tan, Kathleen Sullivan
  • Galanin receptor GALR3 and nucleotides encoding same
    Publication number: 20030023074
    Abstract: A new galanin receptor, GALR3, is described. Also provided are nucleic acids encoding same and various assays to identify ligands particular to said receptor. Ligands so identified are useful for the treatment of obesity, treatment of pain, and treatment of cognitive disorders.
    Type: Application
    Filed: August 6, 2002
    Publication date: January 30, 2003
    Applicant: Merck & Co., Inc.
    Inventors: Andrew D. Howard, Margaret A. Cascieri, Roy G. Smith, Kathleen A. Sullivan, Carina Tan, Leonardus H.T. Van Der Ploeg, Kevin R. Lynch
  • Nucleotide encoding human galanin receptor 3 (GALR3)
    Patent number: 6511827
    Abstract: A new galanin receptor, GALR3, is described. Also provided are nucleic acids encoding same and various assays to identify ligands particular to said receptor. Ligands so identified are useful for the treatment of obesity, treatment of pain, and treatment of cognitive disorders.
    Type: Grant
    Filed: June 16, 2000
    Date of Patent: January 28, 2003
    Assignee: Merck & Co., Inc.
    Inventors: Andrew D. Howard, Margaret A. Cascieri, Roy G. Smith, Kathleen A. Sullivan, Carina Tan, Leonardus H. T. Van Der Ploeg, Kevin R. Lynch
  • Nucleic acid encoding mouse galanin receptor (GALR2)
    Patent number: 6337206
    Abstract: A new galanin receptor, GALR2, is described. Also provided are nucleic acids encoding same and various assays to identify ligands particular to said receptor. Ligands so identified are useful for the treatment of obesity, treatment of pain, and treatment of cognitive disorders.
    Type: Grant
    Filed: December 18, 1997
    Date of Patent: January 8, 2002
    Assignees: Merck & Co., Inc., Board of Regents, The University of Texas System
    Inventors: Carina Tan, Lee F. Kolakowski, Jr.
  • Nucleic acid encoding rat galanin receptor (GALR2)
    Patent number: 6287855
    Abstract: A new galanin receptor, GALR2, is described. Also provided are nucleic acids encoding same and various assays to identify ligands particular to said receptor. Ligands so identified are useful for the treatment of obesity, treatment of pain, and treatment of cognitive disorders.
    Type: Grant
    Filed: December 18, 1997
    Date of Patent: September 11, 2001
    Assignee: Merck & Co., Inc.
    Inventors: Carina Tan, Kathleen Sullivan