Patents by Inventor CARL BROWN III

CARL BROWN III has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Signal propagation biomolecules, devices and methods
    Patent number: 10221446
    Abstract: This disclosure describes a structured polynucleotide, devices that include the structured polynucleotide, and methods involving the structured polynucleotide and/or devices. Generally, the structured polynucleotide includes five domains. A first domain acts as a toehold for an input DNA logic gate to initiate binding to an SCS biomolecule. A second domain acts as a substrate recognition sequence for an upstream DNA logic gate. A third domain acts as a toehold for a output DNA logic gate to initiate binding of the SCS biomolecule to the gate. A fourth domain acts as an effector sequence to alter the state of the output logic gate. A fifth domain acts as a cage sequence to lock the effector sequence in an inactive state until an input gate binds to the structured polynucleotide.
    Type: Grant
    Filed: October 3, 2016
    Date of Patent: March 5, 2019
    Assignee: STC.UNM
    Inventors: Carl Brown, III, Steven Wayde Graves, Darko Stefanovic, Matthew Richard Lakin
  • Signal propagation biomolecules, devices and methods
    Patent number: 9476090
    Abstract: This disclosure describes a structured polynucleotide, devices that include the structured polynucleotide, and methods involving the structured polynucleotide and/or devices. Generally, the structured polynucleotide includes five domains. A first domain acts as a toehold for an input DNA logic gate to initiate binding to an SCS biomolecule. A second domain acts as a substrate recognition sequence for an upstream DNA logic gate. A third domain acts as a toehold for a output DNA logic gate to initiate binding of the SCS biomolecule to the gate. A fourth domain acts as an effector sequence to alter the state of the output logic gate. A fifth domain acts as a cage sequence to lock the effector sequence in an inactive state until an input gate binds to the structured polynucleotide.
    Type: Grant
    Filed: May 21, 2014
    Date of Patent: October 25, 2016
    Assignee: STC.UNM
    Inventors: Carl Brown, III, Steven Wayde Graves, Darko Stefanovic, Matthew Richard Lakin
  • SIGNAL PROPAGATION BIOMOLECULES, DEVICES AND METHODS
    Publication number: 20140349276
    Abstract: This disclosure describes a structured polynucleotide, devices that include the structured polynucleotide, and methods involving the structured polynucleotide and/or devices. Generally, the structured polynucleotide includes five domains. A first domain acts as a toehold for an input DNA logic gate to initiate binding to an SCS biomolecule. A second domain acts as a substrate recognition sequence for an upstream DNA logic gate. A third domain acts as a toehold for a output DNA logic gate to initiate binding of the SCS biomolecule to the gate. A fourth domain acts as an effector sequence to alter the state of the output logic gate. A fifth domain acts as a cage sequence to lock the effector sequence in an inactive state until an input gate binds to the structured polynucleotide.
    Type: Application
    Filed: May 21, 2014
    Publication date: November 27, 2014
    Applicant: STC.UNM
    Inventors: CARL BROWN III, STEVEN WAYDE GRAVES, DARKO STEFANOVIC, MATTHEW RICHARD LAKIN