Patents by Inventor Carl C. Ward

Carl C. Ward has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COVALENT TARGETING OF E3 LIGASES
    Publication number: 20210369731
    Abstract: Disclosed herein, inter alia, are compositions and methods for targeting E3 ligases. In an aspect is a targeted protein degrader including 1) a targeted protein binder and 2) an E3 Ubiquitin ligase binder, wherein the E3 Ubiquitin ligase is human RNF4 or human RNF114. In an aspect is provided a pharmaceutical composition including a compound as described herein, including embodiments, and a pharmaceutically acceptable excipient.
    Type: Application
    Filed: October 9, 2019
    Publication date: December 2, 2021
    Inventors: Jessica Spradlin, Carl C. Ward, Daniel K. Nomura, Markus Schirle, John A. Tallarico, Jeffrey McKenna, Thomas John Maimone, Xirui Hu
  • COMPOSITIONS AND METHODS FOR MODULATING PPP2R1A
    Publication number: 20200054651
    Abstract: Disclosed herein, inter alia, are compositions and methods useful for modulating PPP2R1 A and for the treatment of cancer.
    Type: Application
    Filed: February 2, 2018
    Publication date: February 20, 2020
    Inventors: Daniel K. Nomura, Elizabeth A. Moore, Carl C. Ward, Leslie A. Bateman, Tucker R. Huffman, David K. Miyamoto, Jessica Spradlin