Patents by Inventor Carl D. Novina

Carl D. Novina has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ENGINEERED MICROORGANISMS FOR DETECTION OF DISEASED CELLS
    Publication number: 20240118283
    Abstract: The present invention relates to, inter alia, engineered microorganisms expressing (i) a surface protein, which specifically interacts cell membrane receptors that are specifically exposed to the luminal side of epithelial cells of diseased gastrointestinal tissue, and (ii) a secretable biomarker. The engineered bacteria of the present technology are useful for detecting diseased gastrointestinal tissue.
    Type: Application
    Filed: December 8, 2023
    Publication date: April 11, 2024
    Inventors: Jeffrey Wagner, Fred H. Mermelstein, Carl D. Novina, Robert Distel, Steven Neier, Barry Polisky
  • HIV therapeutic
    Publication number: 20040248296
    Abstract: The present invention provides siRNA methods and compositions for inhibiting HIV infection and/or replication, as well as systems for identifying effective siRNAs for inhibiting HIV and systems for studying HIV infective mechanisms. The invention also provides methods and compositions for inhibiting infection, pathogenicity and/or replication of an infectious agent; for example, by using siRNAs to inhibit host cell gene expression.
    Type: Application
    Filed: March 20, 2003
    Publication date: December 9, 2004
    Inventors: Paul J. Beresford, Judy Lieberman, Michael F. Murray, Carl D. Novina, Phillip A. Sharp