Abstract: The present invention is a process for preparing soft tissue such as tendons, ligaments, cartilage, fascia, dermis, human valves and human veins for implant in a human and removes cellular components and forms an decellular matrix having as major components collagens and elastins while sterilizing the tissue. The process comprises the following steps: (1) isolating from a suitable donor a desired soft tissue sample of the biological material; (2) processing and decellularizing the soft tissue including inspection for visual defects, trimming and soaking the tissue in a detergent depending on whether the tissue is fascia or dermis and rinsing same with sterile water; (3) sterilizing the soft tissue in a vacuum and soaking the tissue in an antibiotic composition or peracetic acid depending on whether the soft tissue is fascia or dermis and rinsing same; (4) processing the tissue by cutting the tissue to size and perforating the tissue; and (5) dipping the tissue in 70% ethanol and packaging the tissue.

Abstract: The invention is directed toward a formable ceramic composition for application to a bone defect site which comprises a ceramic compound of beta tricalcium phosphate particles. The particle size ranges from about 40 microns to 500 microns and is mixed in a hydrogel carrier containing citric acid buffer, the hydrogel component of the carrier ranging from about 1.0 to 5.0% of the composition and the composition has a pH between 7.0 to 7.8.