Patents by Inventor Carl DeSelm

Carl DeSelm has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS OF TREATMENT FOR CANCERS
    Publication number: 20250152624
    Abstract: Among the various aspects of the present disclosure is the provision of compositions and methods of making modified chimeric antigen receptor dendritic cells (CAR-DCs) and methods of use thereof. CAR-DCs can be used for the treatment of tumors and cancers, particularly solid tumors (as well as liquid tumors, blood cancer, and metastatic cancer).
    Type: Application
    Filed: November 2, 2022
    Publication date: May 15, 2025
    Inventors: Carl DeSelm, Shelby Namen
  • CHIMERIC ANTIGEN RECEPTOR DENDRITIC CELLS (CAR-DCS) AND METHODS OF MAKING AND USING SAME
    Publication number: 20230355765
    Abstract: Among the various aspects of the present disclosure is the provision of compositions and methods of making modified chimeric antigen receptor dendritic cells (CAR-DCs) and methods of use thereof. CAR-DCs can be used for the treatment of tumors and cancers, particularly solid tumors (as well as liquid tumors, blood cancer, and metastatic cancer).
    Type: Application
    Filed: December 16, 2020
    Publication date: November 9, 2023
    Inventor: CARL DESELM
  • LOW DOSE RADIATION CONDITIONING FOR IMMUNOTHERAPY
    Publication number: 20210236554
    Abstract: The present disclosure provides methods and compositions for treating cancers and pathogens. It relates to an immunoresponsive cell comprising an antigen-recognizing receptor (e.g., a chimeric antigen receptor (CAR) or a T cell receptor (TCR)), and expressing a secretable TRAIL polypeptide.
    Type: Application
    Filed: April 19, 2021
    Publication date: August 5, 2021
    Applicant: MEMORIAL SLOAN-KETTERING CANCER CENTER
    Inventors: Michel Sadelain, Carl DeSelm