Patents by Inventor Carl Gruber
Carl Gruber has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230218735Abstract: In one aspect, the invention relates to an immunogenic composition that includes a Clostridium difficile toxoid A and/or a C. difficile toxoid B, and methods of use thereof. In another aspect, the invention relates to a method for eliciting an immune response in a human against a C. difficile infection. The method includes administering to the human an effective dose of a composition, which includes a C. difficile toxoid, wherein the composition is administered at least two times, and wherein the immune response against C. difficile toxin A and/or toxin B is sustained.Type: ApplicationFiled: June 17, 2021Publication date: July 13, 2023Inventors: Annaliesa Sybil Anderson, Alexey Vyacheslavovitch Gribenko, William Carl Gruber, Kathrin Ute Jansen, Lakshmi Khandke, Nicholas Randolph Everard Kitchin, Jody Lawrence, Yahong Peng, Michael William Pride, Christopher Frederick Webber, Sabine Susanne Wellnitz, Zhuobiao Yi
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Patent number: 6017794Abstract: An integrated thin film transistor on insulator circuit made up of a number of thin film transistors formed with small feature size and densely packed so as to allow interconnection as a complex circuit. An insulating substrate, preferably flexible, serves as the support layer for the integrated circuit. Control gate metallization is carried on the insulating substrate, a dielectric layer is deposited over the control gate, and an amorphous silicon layer with doped source and drain regions deposited on the dielectric layer. Trenches are formed to remove the amorphous silicon material between transistors to allow highly dense circuit packing. An upper interconnect level which forms connections to the source and drain and gate regions of the thin film transistors, also interconnects the transistors to form more complex circuit structures. Due to the dense packing of the transistors allowed by the trench isolation, the interconnecting foils can be relatively short, increasing the speed of the circuit.Type: GrantFiled: November 20, 1997Date of Patent: January 25, 2000Assignee: Iowa State University Research FoundationInventors: Stanley G. Burns, Carl Gruber, Howard R. Shanks, Alan P. Constant, Allen R. Landin, David H. Schmidt
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Patent number: 5856690Abstract: A thin film floating gate transistor with improved dielectric structure. The dielectric structure serves the purpose of encapsulating the floating gate and also interfacing with the semiconductor material, .alpha.-Si:H. It thus must meet a variety of requirements. In order to provide long memory retention times, the dielectric material, at least in the regions encapsulating the floating gate, must have a high resistivity, on the order of 10.sup.17 ohm-cm or better. Silicon dioxide is the preferred material for encapsulating the floating gate. However, since silicon dioxide creates a high density of defect state when interfaced with the .alpha.-Si:H layer. An interface layer, substantially free of oxide, is interposed between the high resistivity layer and the .alpha.-Si:H. Preferably, the interface portion of the dielectric layer is silicon nitride. In some cases, it is desirable to replace the entire dielectric structure, or at least the interface layer with aluminum nitride.Type: GrantFiled: December 10, 1996Date of Patent: January 5, 1999Assignee: Iowa State University Research FoundationInventors: Stanley G. Burns, Carl Gruber, Howard R. Shanks, Allan P. Constant, Allen R. Landin, David H. Schmidt
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Patent number: 5742075Abstract: An integrated thin film transistor on insulator circuit made up of a number of thin film transistors formed with small feature size and densely packed so as to allow interconnection as a complex circuit. An insulating substrate, preferably flexible, serves as the support layer for the integrated circuit. Control gate metallization is carried on the insulating substrate, a dielectric layer is deposited over the control gate, and an amorphous silicon layer with doped source and drain regions deposited on the dielectric layer. Trenches are formed to remove the amorphous silicon material between transistors to allow highly dense circuit packing. An upper interconnect level which forms connections to the source and drain and gate regions of the thin film transistors, also interconnects the transistors to form more complex circuit structures. Due to the dense packing of the transistors allowed by the trench isolation, the interconnecting foils can be relatively short, increasing the speed of the circuit.Type: GrantFiled: November 18, 1996Date of Patent: April 21, 1998Assignee: Iowa State University Research Foundation, Inc.Inventors: Stanley G. Burns, Carl Gruber, Howard R. Shanks, Alan P. Constant, Allen R. Landin, David H. Schmidt
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Patent number: 5635123Abstract: Fiber-reinforced protein-based biocomposite particulate material containing a legume-based thermosetting resin and cellulosic material, and rigid biocomposite pressure-formed materials produced therefrom, are provided. The particulate material and resultant pressure-formed materials contain the legume-based resin and fibrous cellulosic material in amounts such that the ratio of cellulose solids to resin solids is about 0.8:1.0 to about 1.5:1.0. Particularly preferred pressure-formed materials also include a secondary thermosetting binder, such as an isocyanate.Type: GrantFiled: June 7, 1995Date of Patent: June 3, 1997Assignee: Phenix Biocomposites, Inc.Inventors: Michael J. Riebel, Paul L. Torgusen, Kenneth D. Roos, Donald E. Anderson, Carl Gruber
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Patent number: 5611882Abstract: A cellulose mixture including a protein based adhesive binder and colorant. The mixture can be compression molded or extruded and upon curing in the presence of microwave or radio frequency energy or in thermally controlled appliance, produces board or shape formed stock. The produced stock exhibits colorations and a grain pattern comparable to natural stone. Unlike stone, the material exhibits a light weight, low density, structural rigidity and ready machinability. A preferred method includes admixing separate, colorized batches of feedstock, each feedstock includes shredded waste newsprint, soybean flour, water and a colorant; reducing the moisture content of each feedstock or a proportioned admixture of several feedstocks, such as by air drying or compressing or performing the admixture in the presence of heat; compacting the admixture to final shape; and curing the shaped material. Final forming and finishing apparatus complete the process.Type: GrantFiled: May 2, 1994Date of Patent: March 18, 1997Assignee: Phenix Biocomposites, Inc.Inventors: Michael J. Riebel, Donald E. Anderson, Carl Gruber, Paul Torgusen, Robert DeGezelle, Molly DeGezelle
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Patent number: 5593625Abstract: Fiber-reinforced protein-based biocomposite particulate material containing a legume-based thermosetting resin and cellulosic material, and rigid biocomposite pressure-formed materials produced therefrom, are provided. The particulate material and resultant pressure-formed materials contain the legume-based resin and fibrous cellulosic material in amounts such that the ratio of cellulose solids to resin solids is about 0.8:1.0 to about 1.5:1.0. Particularly preferred pressure-formed materials also include a secondary thermosetting binder, such as an isocyanate.Type: GrantFiled: June 10, 1994Date of Patent: January 14, 1997Assignee: Phenix Biocomposites, Inc.Inventors: Michael J. Riebel, Paul L. Torgusen, Kenneth D. Roos, Donald E. Anderson, Carl Gruber
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Patent number: 4921296Abstract: A vehicle side door mirror glare screen device (34) is disclosed as including a lower mount (36) having a lower tapered end (38) that is inserted between the door window and the door and as also having an upper end that projects upwardly with an inner surface that mounts a glare screen (46) of a sheet-like construction having a sufficient size and shape to screen light glare from an associated exterior door mirror. The lower end (38) of the lower mount (36) preferably has a taper (54) that facilitates its insertion and also preferably has a generally pointed construction (56). Glare screen (46) also preferably has inclined edges (58) that facilitate its positioning and has a horizontally elongated shape that is preferably oblong. A transparent tinted plastic is preferably utilized to fabricate the glare screen (46).Type: GrantFiled: April 3, 1989Date of Patent: May 1, 1990Assignee: Carl A. GruberInventor: Carl A. Gruber