Patents by Inventor Carl Hacker

Carl Hacker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230371984
    Abstract: Among the various aspects of the present disclosure is the provision of devices, systems, and methods for tracking the positions and orientations of at least one bone screw implanted within a surgical site. The disclosed device includes an extension that includes an extension base configured to couple to the bone screw, a marker arm coupled at one end to the extension base in a hinged arrangement, and an optical marker attached to a free end of the marker arm opposite the hinged attachment. The optical marker includes a pair of lenticular arrays in a coplanar arrangement in which the major axes of the lenticular arrays are mutually perpendicular. Each lenticular array is configured to display different hues at different viewing angles. The disclosed method includes transforming a single image of a surgical site containing at least one bone screw and extension into the global positions of each bone screw based on the pixel positions and hues corresponding to the lenticular arrays of each optical marker.
    Type: Application
    Filed: May 17, 2023
    Publication date: November 23, 2023
    Applicants: Washington University, The George Washington University
    Inventors: Eric Leuthardt, Guy Genin, Peter Brunner, Robert Pless, Camilo Molina, Carl Hacker, Daniel Moran, Alicia Repka, Halle Lowe, Jacob Sandler
  • Publication number: 20230306595
    Abstract: A method for selecting a seed region for use in a seed-based cortical functional mapping method includes providing at least one RSN map of at least one subject, each of the at least one RSN maps comprising a plurality of functional voxels within a brain of each of the at least one subjects, each functional voxel of the plurality of functional voxels associated with a probability of membership in an RSN. A subset of the functional voxels characterizing a contiguous region is selected as the seed region, each functional voxel of the seed region having a probability of membership in the RSN above a threshold value.
    Type: Application
    Filed: May 23, 2023
    Publication date: September 28, 2023
    Applicant: Washington University
    Inventors: Eric Leuthardt, Carl Hacker, Shan Siddiqi, Tim Laumann, Andy Daniel
  • Patent number: 11704790
    Abstract: A target location for a therapeutic intervention is determined in a subject with a neurological disorder. The target location is selected within at least one resting state network (RSN) map according to a predetermined criterion for the neurological disorder. The at least one RSN map includes a plurality of functional voxels within a brain of the subject, and each functional voxel of the plurality of functional voxels is associated with a probability of membership in an RSN. Instructions are transmitted to a treatment system that cause operation to be performed on the selected target location.
    Type: Grant
    Filed: September 25, 2018
    Date of Patent: July 18, 2023
    Assignee: Washington University
    Inventors: Eric Leuthardt, Carl Hacker, Shan Siddiqi, Tim Laumann, Andy Daniel
  • Publication number: 20230181119
    Abstract: A computing device for use in a system for mapping brain activity of a subject includes a processor. The processor is programmed to select a plurality of measurements of brain activity that is representative of at least one parameter of a brain of the subject during a resting state. Moreover, the processor is programmed to compare at least one data point from each of the measurements with a corresponding data point from a previously acquired data set from at least one other subject. The processor is also programmed to produce at least one map for each of the measurements based on the comparison of the resting state data point and the corresponding previously acquired data point. The processor may also be programmed to categorize the brain activity in a plurality of networks in the brain based on the map.
    Type: Application
    Filed: February 13, 2023
    Publication date: June 15, 2023
    Inventors: Eric Leuthardt, Nicholas Szrama, Carl Hacker, Tim Laumann, Maurizio Corbetta, Abraham Z. Snyder
  • Patent number: 11589826
    Abstract: A computing device for use in a system for mapping brain activity of a subject includes a processor. The processor is programmed to select a plurality of measurements of brain activity that is representative of at least one parameter of a brain of the subject during a resting state. Moreover, the processor is programmed to compare at least one data point from each of the measurements with a corresponding data point from a previously acquired data set from at least one other subject. The processor is also programmed to produce at least one map for each of the measurements based on the comparison of the resting state data point and the corresponding previously acquired data point. The processor may also be programmed to categorize the brain activity in a plurality of networks in the brain based on the map.
    Type: Grant
    Filed: April 15, 2019
    Date of Patent: February 28, 2023
    Assignee: Washington University
    Inventors: Eric Leuthardt, Nicholas Szrama, Carl Hacker, Tim Laumann, Maurizio Corbetta, Abraham Z. Snyder
  • Publication number: 20200237316
    Abstract: A computing device for use in a system for mapping brain activity of a subject includes a processor. The processor is programmed to select a plurality of measurements of brain activity that is representative of at least one parameter of a brain of the subject during a resting state. Moreover, the processor is programmed to compare at least one data point from each of the measurements with a corresponding data point from a previously acquired data set from at least one other subject. The processor is also programmed to produce at least one map for each of the measurements based on the comparison of the resting state data point and the corresponding previously acquired data point. The processor may also be programmed to categorize the brain activity in a plurality of networks in the brain based on the map.
    Type: Application
    Filed: April 15, 2019
    Publication date: July 30, 2020
    Applicant: Washington University
    Inventors: Eric Leuthardt, Nicholas Szrama, Carl Hacker, Tim Laumann, Maurizio Corbetta, Abraham Z. Snyder
  • Publication number: 20190239818
    Abstract: A computing device for use in a system for mapping brain activity of a subject includes a processor. The processor is programmed to select a plurality of measurements of brain activity that is representative of at least one parameter of a brain of the subject during a resting state. Moreover, the processor is programmed to compare at least one data point from each of the measurements with a corresponding data point from a previously acquired data set from at least one other subject. The processor is also programmed to produce at least one map for each of the measurements based on the comparison of the resting state data point and the corresponding previously acquired data point. The processor may also be programmed to categorize the brain activity in a plurality of networks in the brain based on the map.
    Type: Application
    Filed: April 15, 2019
    Publication date: August 8, 2019
    Applicant: Washington University
    Inventors: Eric Leuthardt, Nicholas Szrama, Carl Hacker, Tim Laumann, Maurizio Corbetta, Abraham Z. Snyder
  • Patent number: 10258289
    Abstract: A computing device for use in a system for mapping brain activity of a subject includes a processor. The processor is programmed to select a plurality of measurements of brain activity that is representative of at least one parameter of a brain of the subject during a resting state. Moreover, the processor is programmed to compare at least one data point from each of the measurements with a corresponding data point from a previously acquired data set from at least one other subject. The processor is also programmed to produce at least one map for each of the measurements based on the comparison of the resting state data point and the corresponding previously acquired data point. The processor may also be programmed to categorize the brain activity in a plurality of networks in the brain based on the map.
    Type: Grant
    Filed: September 20, 2018
    Date of Patent: April 16, 2019
    Assignee: Washington University
    Inventors: Eric Leuthardt, Nicholas Szrama, Carl Hacker, Tim Laumann, Maurizio Corbetta, Abraham Z. Snyder
  • Publication number: 20190090749
    Abstract: A method for determining a target location for a therapeutic intervention in a subject with a neurological disorder is disclosed that includes selecting the target location within at least one resting state network (RSN) map according to a predetermined criterion for the neurological disorder. Each of the at least one RSN maps includes a plurality of functional voxels within a brain of the subject, and each functional voxel of the plurality of functional voxels is associated with a probability of membership in an RSN. A method for monitoring an efficacy of a therapeutic intervention in a subject with a neurological disorder is also disclosed that includes comparing at least a portion of at least one pre-treatment RSN map of the subject prior to the therapeutic intervention, at least one post-treatment RSN map of the subject after the therapeutic intervention to determine changes in the at least one post-treatment RSN map.
    Type: Application
    Filed: September 25, 2018
    Publication date: March 28, 2019
    Applicant: Washington University
    Inventors: Eric Leuthardt, Carl Hacker, Shan Siddiqi, Tim Laumann, Andy Daniel
  • Publication number: 20190015050
    Abstract: A computing device for use in a system for mapping brain activity of a subject includes a processor. The processor is programmed to select a plurality of measurements of brain activity that is representative of at least one parameter of a brain of the subject during a resting state. Moreover, the processor is programmed to compare at least one data point from each of the measurements with a corresponding data point from a previously acquired data set from at least one other subject. The processor is also programmed to produce at least one map for each of the measurements based on the comparison of the resting state data point and the corresponding previously acquired data point. The processor may also be programmed to categorize the brain activity in a plurality of networks in the brain based on the map.
    Type: Application
    Filed: September 20, 2018
    Publication date: January 17, 2019
    Applicant: Washington University
    Inventors: Eric Leuthardt, Nicholas Szrama, Carl Hacker, Tim Laumann, Maurizio Corbetta, Abraham Z. Snyder
  • Patent number: 10092246
    Abstract: A computing device for use in a system for mapping brain activity of a subject includes a processor. The processor is programmed to select a plurality of measurements of brain activity that is representative of at least one parameter of a brain of the subject during a resting state. Moreover, the processor is programmed to compare at least one data point from each of the measurements with a corresponding data point from a previously acquired data set from at least one other subject. The processor is also programmed to produce at least one map for each of the measurements based on the comparison of the resting state data point and the corresponding previously acquired data point. The processor may also be programmed to categorize the brain activity in a plurality of networks in the brain based on the map.
    Type: Grant
    Filed: August 15, 2016
    Date of Patent: October 9, 2018
    Assignee: WASHINGTON UNIVERSITY
    Inventors: Eric Leuthardt, Nicholas Szrama, Carl Hacker, Tim Laumann, Maurizio Corbetta, Abraham Z. Snyder
  • Publication number: 20160345911
    Abstract: A computing device for use in a system for mapping brain activity of a subject includes a processor. The processor is programmed to select a plurality of measurements of brain activity that is representative of at least one parameter of a brain of the subject during a resting state. Moreover, the processor is programmed to compare at least one data point from each of the measurements with a corresponding data point from a previously acquired data set from at least one other subject. The processor is also programmed to produce at least one map for each of the measurements based on the comparison of the resting state data point and the corresponding previously acquired data point. The processor may also be programmed to categorize the brain activity in a plurality of networks in the brain based on the map.
    Type: Application
    Filed: August 15, 2016
    Publication date: December 1, 2016
    Inventors: Eric Leuthardt, Nicholas Szrama, Carl Hacker, Tim Laumann, Maurizio Corbetta, Abraham Z. Snyder
  • Patent number: 9480402
    Abstract: A computing device for use in a system for mapping brain activity of a subject includes a processor. The processor is programmed to select a plurality of measurements of brain activity that is representative of at least one parameter of a brain of the subject during a resting state. Moreover, the processor is programmed to compare at least one data point from each of the measurements with a corresponding data point from a previously acquired data set from at least one other subject. The processor is also programmed to produce at least one map for each of the measurements based on the comparison of the resting state data point and the corresponding previously acquired data point. The processor may also be programmed to categorize the brain activity in a plurality of networks in the brain based on the map.
    Type: Grant
    Filed: November 9, 2012
    Date of Patent: November 1, 2016
    Assignee: Washington University
    Inventors: Eric Leuthardt, Nicholas Szrama, Carl Hacker, Tim Laumann, Maurizio Corbetta, Abraham Z. Snyder