Patents by Inventor Carl LeBlond

Carl LeBlond has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for making substituted 8-arylquinolinium benzenesulfonate
    Patent number: 6835837
    Abstract: A substituted 8-aryl quinoline and its benzenesulfonic acid salt is synthesized.
    Type: Grant
    Filed: May 15, 2003
    Date of Patent: December 28, 2004
    Assignee: Merck & Co. Inc.
    Inventors: Richard Desmond, David A. Conlon, Antoinette Drahus, Guo-Jie Ho, Brenda Pipik, Carl Leblond, Anant Vailaya
  • N-heterocyclic bicyclic lactone compounds
    Publication number: 20040087569
    Abstract: Novel N-heterocyclic bicyclic lactone compounds of formula I and its novel hydroxyamide precursors of formula IV, 1
    Type: Application
    Filed: October 28, 2003
    Publication date: May 6, 2004
    Inventors: Todd D. Nelson, Carl LeBlond, Michael H. Kress
  • Process of making n-heterocyclic bicyclic lactone compounds from ketoamides
    Publication number: 20040087790
    Abstract: A process of preparing a compound of Formula I 1
    Type: Application
    Filed: October 28, 2003
    Publication date: May 6, 2004
    Inventors: Todd D. Nelson, Carl LeBlond, Jeffrey V. Mitten
  • Process for making substituted 8-arylquinolinium benzenesulfonate
    Publication number: 20040044213
    Abstract: A substituted 8-aryl quinoline and its benzenesulfonic acid salt is synthesized.
    Type: Application
    Filed: May 15, 2003
    Publication date: March 4, 2004
    Inventors: Richard Desmond, David A. Conlon, Antoinette Drahus, Guo-Jie Ho, Brenda Pipik, Carl Leblond, Anant Vailaya
  • Heterogeneously catalyzed process for cross coupling alkenyl halides with boronic acids
    Patent number: 6603013
    Abstract: The present invention relates to a process wherein heterogeneous finely-dispersed palladium catalysts are used in a cross-coupling reaction of alkenyl halides and aryl or heteroaryl boronic acids in the presence of base in an aprotic solvent to produce aryl- or heteroaryl-olefin compounds of Formula I:
    Type: Grant
    Filed: July 16, 2001
    Date of Patent: August 5, 2003
    Assignee: Merck & Co., Inc.
    Inventors: Yongkui Sun, Carl LeBlond, John R. Sowa, Jr.
  • Process for making substituted 8-arylquinolinium benzenesulfonate
    Publication number: 20030097001
    Abstract: A substituted 8-aryl quinoline and its benzenesulfonic acid salt is synthesized.
    Type: Application
    Filed: December 18, 2001
    Publication date: May 22, 2003
    Inventors: Richard Desmond, David A. Conlon, Antoinette Drahus, Guo-Jie Ho, Brenda Pipik, Carl Leblond, Anant Vailaya
  • Heterogeneously catalyzed process for cross coupling alkenyl halides with boronic acids
    Publication number: 20020045775
    Abstract: The present invention relates to a process wherein heterogeneous finely dispersed palladium catalysts are used for cross coupling of alkenyl halides and boronic acids in the presence of base in an aprotic solvent to produce aryl- or heteroaryl-olefin compounds. The process provides for use with either electron-withdrawing or electron-donating substituents for cross coupling of alkyl halides with boronic acids.
    Type: Application
    Filed: July 16, 2001
    Publication date: April 18, 2002
    Inventors: Yongkui Sun, Carl LeBlond, John R. Sowa
  • Heterogeneously catalyzed process for cross coupling aryl chlorides with aryl boronic acids
    Publication number: 20020016512
    Abstract: This invention relates to a ligandless process wherein heterogeneous Pd catalysts are used to activate aryl and heteroaryl chlorides for cross coupling aryl and heteroaryl chlorides and boronic acids. The process provides for use with either electron-withdrawing or electron-donating substituents, for cross coupling with boronic acids.
    Type: Application
    Filed: July 16, 2001
    Publication date: February 7, 2002
    Inventors: Yongkui Sun, Carl LeBlond, John R. Sowa
  • Stereoselective process for enalapril
    Patent number: 6025500
    Abstract: The invention relates to an improved stereoselective heterogenous catalytic reductive amination between ethyl 2-oxo-4-phenylbutyrate and alanylproline using hydrogen, a catalyst and one or more additives to produce the ACE inhibitor, enalapril.
    Type: Grant
    Filed: September 17, 1999
    Date of Patent: February 15, 2000
    Assignee: Merck & Co., Ltd.
    Inventors: Mark A. Huffman, Paul J. Reider, Carl Leblond, Yongkui Sun
  • Process for indinavir intermediate
    Patent number: 5981759
    Abstract: An intermediate in the synthesis of indinavir is prepared by iodohydroxylating an allyl acetonide by hypoiodous acid generated in situ from sodium hypochlorite and sodium iodide.
    Type: Grant
    Filed: June 17, 1998
    Date of Patent: November 9, 1999
    Assignee: Merck & Co., Inc.
    Inventors: Yongku Sun, Frank P. Gortsema, Carl Leblond, Kai Rossen