Patents by Inventor Carl M. Mendel

Carl M. Mendel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Treatment of neuropathic pain or fibromyalgia
    Patent number: 6803387
    Abstract: A compound of formula I or a pharmaceutically acceptable salt thereof in which R1 and R2 are independently H or methyl (for example N,N-dimethyl-1-[1-(4-chlorophenyl) cyclobutyl]-3-methylbutyl amine hydrochloride optionally in the form of its monohydrate) is used for treating fibromyalgia or neuropathic pain, such as pain associated with diabetes mellitus, shingles, nerve injury and varied peripheral neuropathies.
    Type: Grant
    Filed: March 17, 2000
    Date of Patent: October 12, 2004
    Assignee: Abbott GmbH & Co. KG
    Inventors: Carl M. Mendel, Timothy B. Seaton, Steve P. Weinstein, Edward Chong
  • Treatment of neuropathic pain or fibromyalgia
    Publication number: 20040198837
    Abstract: A compound of formula I 1
    Type: Application
    Filed: April 21, 2004
    Publication date: October 7, 2004
    Inventors: Carl M. Mendel, Timothy B. Seaton, Steve P. Weinstein, Edward Chong
  • Prevention or treatment of insomnia with a neurokinin-1 receptor antagonist
    Patent number: 6525073
    Abstract: A tachykinin antagonist is useful, alone or in conjunction with other agents, for altering circadian rhythmicity and alleviating circadian rhythm disorders and for enhancing and improving the quality of sleep.
    Type: Grant
    Filed: October 16, 2001
    Date of Patent: February 25, 2003
    Assignee: Merck & Co. Inc.
    Inventors: Carl M. Mendel, Joanne Waldstreicher
  • Weight loss after pregnancy
    Publication number: 20030013735
    Abstract: A compound of formula I 1
    Type: Application
    Filed: March 17, 2000
    Publication date: January 16, 2003
    Inventors: Carl M Mendel, Timothy B Seaton, Steve P Weinstein
  • Method of controlling weight gain associated with therapeutic drugs
    Publication number: 20030008897
    Abstract: A compound of formula I 1
    Type: Application
    Filed: March 17, 2000
    Publication date: January 9, 2003
    Inventors: Carl M. Mendel, Timothy B. Seaton, Steve P. Weinstein
  • Treatment of premenstrual syndrome
    Publication number: 20020132856
    Abstract: A compound of formula I 1
    Type: Application
    Filed: March 17, 2000
    Publication date: September 19, 2002
    Inventors: Carl M. Mendel, Timothy B. Seaton, Steve P. Weinstein
  • Control of metabolism
    Patent number: 6441046
    Abstract: A compound of formula I or a pharmaceutically acceptable salt thereof in which R1 and R2 are independently H or methyl (for example N,N-dimethyl-1-[1-(4-chlorophenyl)cyclobutyl ]-3-methylbutyl amine hydrochloride optionally in the form of its monohydrate) is used for treating metabolic disorders, such as increased non-exercise activity thermogenesis or increased metabolic rate.
    Type: Grant
    Filed: March 17, 2000
    Date of Patent: August 27, 2002
    Assignee: Abbott GmbH & Co. KG
    Inventors: Carl M. Mendel, Timothy B. Seaton, Steve P. Weinstein
  • Treatment of cardiovascular disease
    Patent number: 6433020
    Abstract: A compound of formula I or a pharmaceutically acceptable salt thereof in which R1 and R2 are independently H or methyl (for example N,N-dimethyl-1-[1-(4-chlorophenyl)cyclobutyl]-3-methylbutyl amine hydrochloride optionally in the form of its monohydrate) is used for treating cardiovascular disease, such as dyslipidaemia or carotid intimal medial thickening.
    Type: Grant
    Filed: March 17, 2000
    Date of Patent: August 13, 2002
    Assignee: Knoll Pharmaceutical Company
    Inventors: Carl M. Mendel, Timothy B. Seaton, Steve P. Weinstein
  • Treatment of pulmonary hypertension
    Patent number: 6403650
    Abstract: A compound of formula I or a pharmaceutically acceptable salt thereof in which R1 and R2 are independently H or methyl (for example N,N-dimethyl-1-[1-4chlorophenyl)cyclobutyl]-3-methylbutyl amine hydrochloride optionally in the form of its monohydrate) is used for treating pulmonary hypertension, particularly in patients who take certain anorectic medications.
    Type: Grant
    Filed: March 17, 2000
    Date of Patent: June 11, 2002
    Assignee: Knoll Pharmaceutical Company
    Inventors: Carl M. Mendel, Timothy B. Seaton, Steve P. Weinstein
  • Treatment to lower platelet adhesiveness
    Patent number: 6380260
    Abstract: A compound of formula I or a pharmaceutically acceptable salt thereof in which R1 and R2 are independently H or methyl (for example N,N-dimethyl-1-[1-(4-chlorophenyl) cyclobutyl]-3-methylbutyl amine hydrochloride optionally in the form of its monohydrate) is used for decreasing platelet adhesiveness.
    Type: Grant
    Filed: March 17, 2000
    Date of Patent: April 30, 2002
    Assignee: Knoll Pharmaceutical Company
    Inventors: Carl M. Mendel, Timothy B. Seaton, Steve P. Weinstein
  • Treatment of pain
    Patent number: 6376553
    Abstract: A compound of formula I or a pharmaceutically acceptable salt thereof in which R1 and R2 are independently H or methyl (for example N,N-dimethyl-1-[1-(4-chlorophenyl)cyclobutyl]-3-methylbutyl amine hydrochloride optionally in the form of its monohydrate) is used for treating pain such as low back pain.
    Type: Grant
    Filed: March 17, 2000
    Date of Patent: April 23, 2002
    Assignee: Knoll Pharmaceutical Company
    Inventors: Carl M. Mendel, Timothy B. Seaton, Steve P. Weinstein
  • Treatment of gallstones
    Patent number: 6376552
    Abstract: A compound of formula I or a pharmaceutically acceptable salt thereof in which R1 and R2 are independently H or methyl (for example N,N-dimethyl-1-[1-(4-chlorophenyl)cyclobutyl]-3-methylbutyl amine hydrochloride optionally in the form of its monohydrate) is used for treating gallstones, particularly gallstones associated with weight loss or associated with gall bladder disease related to obesity.
    Type: Grant
    Filed: March 17, 2000
    Date of Patent: April 23, 2002
    Assignee: Knoll Pharmaceutical Company
    Inventors: Carl M. Mendel, Timothy B. Seaton, Steve P. Weinstein
  • Treatment of chronic fatigue syndrome
    Patent number: 6376551
    Abstract: A compound of formula I or a pharmaceutically acceptable salt thereof in which R1 and R2 are independently H or methyl (for example N,N-dimethyl-1-[1-(4-chlorophenyl)cyclobutyl]-3-methylbutyl amine hydrochloride optionally in the form of its monohydrate) is used for treating chronic fatigue syndrome.
    Type: Grant
    Filed: March 17, 2000
    Date of Patent: April 23, 2002
    Assignee: Knoll Pharmaceutical Company
    Inventors: Carl M. Mendel, Timothy B. Seaton, Steve P. Weinstein
  • Treatment of hyperactivity disorders
    Patent number: 6372798
    Abstract: A compound of formula I or a pharmaceutically acceptable salt thereof in which R1 and R2 are independently H or methyl (for example N,N-dimethyl-1-[1-(4-chlorophenyl)cyclobutyl]-3-methylbutyl amine hydrochloride optionally in the form of its monohydrate) is used for treating hyperactivity disorders, such as attention deficit hyperactivity disorder and hyperkinetic disorder.
    Type: Grant
    Filed: March 17, 2000
    Date of Patent: April 16, 2002
    Assignee: Knoll Pharmaceutical Company
    Inventors: Carl M. Mendel, Timothy B. Seaton, Steve P. Weinstein
  • Treatment of menstrual function
    Patent number: 6372797
    Abstract: A compound of formula I or a pharmaceutically acceptable salt thereof in which R1 and R2 are independently H or methyl (for example N,N-dimethyl-1-[1-(4-chlorophenyl)cyclobutyl]-3-methylbutyl amine hydrochloride optionally in the form of its monohydrate) is used for treating menstrual function and infertility.
    Type: Grant
    Filed: March 17, 2000
    Date of Patent: April 16, 2002
    Assignee: Knoll Pharmaceutical Company
    Inventors: Carl M. Mendel, Timothy B. Seaton, Steve P. Weinstein
  • Treatment of orthostatic hypotension
    Patent number: 6365632
    Abstract: A compound of formula I or a pharmaceutically acceptable salt thereof in which R1 and R2 are independently H or methyl (for example N,N-dimethyl-1-[1-(4-chlorophenyl)cyclobutyl]-3-methylbutyl amine hydrochloride optionally in the form of its monohydrate) is used for treating orthostatic hypotension.
    Type: Grant
    Filed: March 17, 2000
    Date of Patent: April 2, 2002
    Assignee: Knoll Pharmaceuticals Company
    Inventors: Carl M. Mendel, Timothy B. Seaton, Steve P. Weinstein
  • Method of treating eating disorders
    Patent number: 6365633
    Abstract: A compound of formula I or a pharmaceutically acceptable salt thereof in which R1 and R2 are independently H or methyl (for example N,N-dimethyl-1-[1-(4-chlorophenyl)cyclobutyl]-3-methylbutyl amine hydrochloride optionally in the form of its monohydrate) is used for treating eating disorders, such as anorexia nervosa, bulimia nervosa, weight-gain after smoking cessation, snacking or binge eating.
    Type: Grant
    Filed: March 17, 2000
    Date of Patent: April 2, 2002
    Assignee: Knoll Pharmaceutical Company
    Inventors: Sharon C. Cheetham, David J. Heal, Carl M. Mendel, Timothy B. Seaton, Steve P. Weinstein
  • Method of treating sleep apnoea
    Patent number: 6365631
    Abstract: A compound of formula I or a pharmaceutically acceptable salt thereof in which R1 and R2 are independently H or methyl, including individual enantiomers or racemates thereof, (for example N,N-dimethyl-1-[1-(4-chlorophenyl)cyclobutyl]-3-methylbutylamine hydrochloride optionally in the form of its monohydrate) is used for treating sleeping disorders including sleep apnoea and snoring.
    Type: Grant
    Filed: March 17, 2000
    Date of Patent: April 2, 2002
    Assignee: Knoll Pharmaceutical Company
    Inventors: Sharon C. Cheetham, David J. Heal, Carl M. Mendel, Timothy B. Seaton, Steve P. Weinstein, Anton Safer
  • Prevention or treatment of insomina with a neurokinin-1 receptor antagonist
    Publication number: 20020035059
    Abstract: A tachykinin antagonist is useful, alone or in conjunction with other agents, for altering circadian rhythmicity and alleviating circadian rhythm disorders and for enhancing and improving the quality of sleep.
    Type: Application
    Filed: October 16, 2001
    Publication date: March 21, 2002
    Applicant: Merck & Co., Inc.
    Inventors: Carl M. Mendel, Joanne Waldstreicher
  • Treatment of pharmacology of drug misuse and other addictive disorders
    Patent number: 6346549
    Abstract: A compound of formula I or a pharmaceutically acceptable salt thereof in which R1 and R2 are independently H or methyl (for example N,N-dimethyl-1-[1-(4-chlorophenyl)cyclobutyl]-3-methylbutyl amine hydrochloride optionally in the form of its monohydrate) is used for treating disorders arising from drug misuse or other addictive disorders.
    Type: Grant
    Filed: March 17, 2000
    Date of Patent: February 12, 2002
    Assignee: Knoll Pharmaceutical Company
    Inventors: Carl M. Mendel, Timothy B. Seaton, Steve P. Weinstein