Patents by Inventor Carl Nicholas Hodge

Carl Nicholas Hodge has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 2-amido-thiazole-based compounds exhibiting ATP-utilizing enzyme inhibitory activity, and compositions, and uses thereof
    Patent number: 7795290
    Abstract: 2-Amido-4-substituted-aryl-thiazole-based compounds exhibiting ATP-utilizing enzyme inhibitory activity, methods of using compounds exhibiting ATP-utilizing enzyme inhibitory activity, and compositions comprising compounds exhibiting ATP-utilizing enzyme inhibitory activity, are disclosed.
    Type: Grant
    Filed: July 3, 2008
    Date of Patent: September 14, 2010
    Assignee: Genentech, Inc.
    Inventors: John K. Dickson, Jr., Carl Nicholas Hodge, Jose Serafin Mendoza, Ke Chen
  • Method for predicting skin sensitizing activity of compounds
    Publication number: 20090069338
    Abstract: Quinoline- and isoquinoline-based compounds exhibiting ATP-utilizing enzyme inhibitory activity, methods of using compounds exhibiting ATP-utilizing enzyme inhibitory activity, and compositions comprising compounds exhibiting ATP-utilizing enzyme inhibitory activity, are disclosed.
    Type: Application
    Filed: November 18, 2008
    Publication date: March 12, 2009
    Inventors: John K. Dickson, JR., Kevin P. Williams, Carl Nicholas Hodge
  • 2-AMIDO-THIAZOLE-BASED COMPOUNDS EXHIBITING ATP-UTILIZING ENZYME INHIBITORY ACTIVITY, AND COMPOSITIONS, AND USES THEREOF
    Publication number: 20090048313
    Abstract: 2-Amido-4-substituted-aryl-thiazole-based compounds exhibiting ATP-utilizing enzyme inhibitory activity, methods of using compounds exhibiting ATP-utilizing enzyme inhibitory activity, and compositions comprising compounds exhibiting ATP-utilizing enzyme inhibitory activity, are disclosed.
    Type: Application
    Filed: July 3, 2008
    Publication date: February 19, 2009
    Applicant: Genentech, Inc.
    Inventors: John K. Dickson, JR., Carl Nicholas Hodge, Jose Serafin Mendoza, Ke Chen
  • Quinoline- and isoquinoline-based compounds exhibiting ATP-utilizing enzyme inhibitory activity, and compositions, and uses thereof
    Patent number: 7452887
    Abstract: Quinoline- and isoquinoline-based compounds exhibiting ATP-utilizing enzyme inhibitory activity, methods of using compounds exhibiting ATP-utilizing enzyme inhibitory activity, and compositions comprising compounds exhibiting ATP-utilizing enzyme inhibitory activity, are disclosed.
    Type: Grant
    Filed: June 3, 2005
    Date of Patent: November 18, 2008
    Assignee: Amphora Discovery Corporation
    Inventors: John K. Dickson, Jr., Kevin P. Williams, Carl Nicholas Hodge
  • 2-AMIDO-4-ISOXAZOLYL THIAZOLE COMPOUNDS EXHIBITING ATP-UTILIZING ENZYME INHIBITORY ACTIVITY, AND COMPOSITIONS, AND USES THEREOF
    Publication number: 20080242709
    Abstract: 2-Amido-4-isoxazolyl thiazole compounds exhibiting ATP-utilizing enzyme inhibitory activity, methods of using compounds exhibiting ATP-utilizing enzyme inhibitory activity, and compositions comprising compounds exhibiting ATP-utilizing enzyme inhibitory activity, are disclosed.
    Type: Application
    Filed: August 9, 2007
    Publication date: October 2, 2008
    Inventors: John K. Dickson, Carl Nicholas Hodge, Ke Chen
  • 2-Amido-thiazole-based compounds exhibiting ATP-utilizing enzyme inhibitory activity, and compositions, and uses thereof
    Patent number: 7410988
    Abstract: 2-Amido-4-substituted-aryl-thiazole-based compounds exhibiting ATP-utilizing enzyme inhibitory activity, methods of using compounds exhibiting ATP-utilizing enzyme inhibitory activity, and compositions comprising compounds exhibiting ATP-utilizing enzyme inhibitory activity, are disclosed.
    Type: Grant
    Filed: August 11, 2005
    Date of Patent: August 12, 2008
    Assignee: Genentech, Inc.
    Inventors: John K. Dickson, Jr., Carl Nicholas Hodge, Jose Serafin Mendoza, Ke Chen
  • Substituted cyclic carbonyls and derivatives thereof useful as retroviral protease inhibitors
    Patent number: 6503898
    Abstract: This invention relates to substituted cyclic carbonyls and derivatives thereof useful as retroviral protease inhibitors, to pharmaceutical compositions comprising such compounds, and to methods of using these compounds for treating viral infection. A representative compound of the invention is the compound of formula: wherein R22 and R23 are allyl.
    Type: Grant
    Filed: July 10, 1998
    Date of Patent: January 7, 2003
    Assignee: Bristol-Myers Squibb Pharma Company
    Inventors: Patrick Yuk-Sun Lam, Prabhakar Kondaji Jadhav, Charles Joseph Eyermann, Carl Nicholas Hodge, George Vincent De Lucca, James David Rodgers
  • 1N-alkyl-n-arylpyrimidinamines and derivatives thereof
    Patent number: 6342503
    Abstract: The present invention provides novel compounds, compounds and pharmaceutical compositions thereof, and methods of using same in the treatment of affective disorders, anxiety, depression, post-traumatic stress disorders, eating disorders, supranuclear palsy, irritable bowel syndrome, immune suppression, Alzheimer'disease, gastrointestinal diseases, anorexia nervosa, drug and alcohol withdrawal symptoms, drug addiction, inflammatory disorders, or fertility problems. The novel compounds provided by this invention are those of formula: wherein R1, R3, R4, R5, Z, Y, V, X, X′, J, K, L, and M are as defined herein.
    Type: Grant
    Filed: January 7, 1998
    Date of Patent: January 29, 2002
    Assignee: DuPont Pharmaceuticals Company
    Inventors: Paul Edward Aldrich, Argyrios Georgios Arvanitis, Robert Scott Cheeseman, Robert John Chorvat, Thomas Eugene Christos, Paul Joseph Gilligan, Dimitri Emil Grigoriadis, Carl Nicholas Hodge, Paul John Krenitsky, Everett Latham Scholfield, Sang William Tam, Zelda Rakowitz Wasserman
  • 1N-alkyl-N-arylpyrimidinamines and derivatives thereof
    Patent number: 6107301
    Abstract: The present invention provides novel compounds, compounds and pharmaceutical compositions thereof, and methods of using same in the treatment of affective disorders, anxiety, depression, post-traumatic stress disorders, eating disorders, supranuclear palsy, irritable bowel syndrome, immune suppression, Alzheimer's disease, gastrointestinal diseases, anorexia nervosa, drug and alcohol withdrawal symptoms, drug addiction, inflammatory disorders, or fertility problems. The novel compounds provided by this invention are those of formula: ##STR1## wherein R.sup.1, R.sup.3, R.sup.4, R.sup.5, Z, Y, V, X, X', J, K, L, and M are as defined herein.
    Type: Grant
    Filed: August 5, 1997
    Date of Patent: August 22, 2000
    Assignee: Dupont Pharmaceuticals Company
    Inventors: Paul Edward Aldrich, Argyrios Georgios Arvanitis, Rajagopal Bakthavatchalam, James Peter Beck, Robert Scott Cheeseman, Robert John Chorvat, Paul Joseph Gilligan, Carl Nicholas Hodge, Zelda Rakowitz Wasserman
  • Substitute caprolactams and derivatives thereof useful for treatment of HIV disease
    Patent number: 5877170
    Abstract: This invention relates to novel substituted caprolactams, including 4-azacaprolactams, and derivatives thereof which inhibit HIV protease and are useful for treatment of HIV disease. Also included in this invention are pharmaceutical compositions containing such caprolactams, and to methods of using such caprolactams for the treatment of HIV disease.
    Type: Grant
    Filed: May 23, 1997
    Date of Patent: March 2, 1999
    Assignee: DuPont Pharmaceuticals Company
    Inventors: Carl Nicholas Hodge, Christina Howard Fernandez, Prabhakar Kondaji Jadhav, Patrick Yuk-Sun Lam
  • Substituted cyclic carbonyls and derivatives thereof useful as retroviral protease inhibitors
    Patent number: 5811422
    Abstract: This invention relates to substituted cyclic carbonyls and derivatives thereof useful as retroviral protease inhibitors, to pharmaceutical compositions comprising such compounds, and to methods of using these compounds for treating viral infection. A representative compound of the invention is the compound of formula: ##STR1## wherein R.sup.22 and R.sup.23 are allyl.
    Type: Grant
    Filed: November 22, 1996
    Date of Patent: September 22, 1998
    Assignee: The DuPont Merck Pharmaceutical Company
    Inventors: Patrick Yuk-Sun Lam, Prabhakar Kondaji Jadhav, Charles Joseph Eyermann, Carl Nicholas Hodge, George Vincent De Lucca, James David Rodgers
  • Substituted 1,4-diazapine caprolactams useful for treatment of HIV disease
    Patent number: 5663333
    Abstract: This invention relates to novel substituted caprolactams, including 4-azacaprolactams, and derivatives thereof which inhibit HIV protease and are useful for treatment of HIV disease. Also included in this invention are pharmaceutical compositions containing such caprolactams, and to methods of using such caprolactams for the treatment of HIV disease.
    Type: Grant
    Filed: March 30, 1993
    Date of Patent: September 2, 1997
    Assignee: The DuPont Merck Pharmaceutical Company
    Inventors: Carl Nicholas Hodge, Christina Howard Fernandez, Prabhakar Kondaji Jadhav, Patrick Yuk-Sun Lam