Patents by Inventor Carl Peter Decicco

Carl Peter Decicco has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hydroxamic acid compounds as metalloprotease and TNF inhibitors
    Patent number: 5703092
    Abstract: The present invention provides novel hydroxamic acids and carbocyclic acids and derivatives thereof and to pharmaceutical compositions and methods of use of these novel compounds for the inhibition of matrixmetalloproteinases, such as stromelysin and other matrix metalloproteinases, and also inhibit the production of tumor necrosis factor (TNF), and are therefore useful for the treatment of arthritis and other related inflammatory diseases.
    Type: Grant
    Filed: April 16, 1996
    Date of Patent: December 30, 1997
    Assignee: The DuPont Merck Pharmaceutical Company
    Inventors: Chu-Biao Xue, William F. DeGrado, Carl Peter DeCicco, Irina Cipora Jacobson
  • Hydroxamic and carbocyclic acids as metalloprotease inhibitors
    Patent number: 5691381
    Abstract: The present invention provides novel hydroxamic acids and carbocyclic acids and derivatives thereof and to pharmaceutical compositions and methods of use of these novel compounds for the inhibition of matrix metalloproteinases, such as stromelysin, and inhibit the production of tumor necrosis factor alpha, and for the treatment of arthritis and other related inflammatory diseases.
    Type: Grant
    Filed: April 16, 1996
    Date of Patent: November 25, 1997
    Assignee: The DuPont Merck Pharmaceutical Company
    Inventors: Irina Cipora Jacobson, Carl Peter Decicco, Robert Joseph Cherney