Abstract: The present invention is a system and method for analyzing medical images and image-derived data. Before the medical image procedure is accomplished, the present invention analyzes and reports on the appropriateness of the proposed procedure based upon known client data. After image and image-derived data is received from an image acquisition device, the present invention validates the data against data validation rules. Once the data is validated, it is analyzed against a knowledgebase to create a proposed diagnosis based on the validated data. The knowledgebase is preferably embodied in a binary cascade system.