Patents by Inventor Carl Thibeault

Carl Thibeault has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 7-hydroxy-indolinyl antagonists of P2Yreceptor
    Patent number: 9540323
    Abstract: The present invention provides compounds of Formula (I): Formula (I) as defined in the specification and compositions comprising any of such novel compounds. These compounds are antagonists of P2Y1 receptor which may be used medicaments.
    Type: Grant
    Filed: July 30, 2013
    Date of Patent: January 10, 2017
    Assignee: Bristol-Myers Squibb Company
    Inventors: Alexandre L'Heureux, Sheldon Hiebert, Carol Hu, Patrick Y. S. Lam, John Lloyd, Zulan Pi, Jennifer X. Qiao, Carl Thibeault, George O. Tora, Wu Yang, Yufeng Wang, Tammy C. Wang, Michael S. Bowsher, Ruel Rejean
  • Inhibitors of cytomegalovirus
    Patent number: 9505775
    Abstract: Compounds of Formula (I) wherein R1, R2, R3A, R3B, Y, Z1 and Z2 are defined herein, are useful for the treatment of cytomegalovirus disease and/or infection.
    Type: Grant
    Filed: October 31, 2013
    Date of Patent: November 29, 2016
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Carl Thibeault, Jean Rancourt, Pierre L. Beaulieu, Anne Décor, Chantal Grand-Maitre, Cyrille Kuhn, Elisia Villemure, Oliver Hucke, Simon Surprenant, Melissa Leblanc, Jean-Eric Lacoste, Benoit Moreau, Eric Jolicoeur
  • 7-hydroxy-spiropipiperidine indolinyl antagonists of P2Yreceptor
    Patent number: 9428504
    Abstract: The present invention provides compounds of Formula (I): as defined in the specification and compositions comprising any of such novel compounds. These compounds are antagonists of P2Y1 receptor and may be used as medicaments in the treatment and/or prophylaxis of thromboembolic disorders.
    Type: Grant
    Filed: July 30, 2013
    Date of Patent: August 30, 2016
    Assignee: Bristol-Myers Squibb Company
    Inventors: Carl Thibeault, Charles G. Clark, Indawati DeLucca, Carol Hui Hu, Yoon Jeon, Patrick Y. S. Lam, Jennifer X. Qiao, Wu Yang, Yufeng Wang, Tammy C. Wang
  • Inhibitors of cytomegalovirus
    Patent number: 9334249
    Abstract: Compounds of Formula (I) wherein n, R1, R1A, R2, R4 and Z are defined herein, are useful for the treatment of cytomegalovirus disease and/or infection.
    Type: Grant
    Filed: October 31, 2013
    Date of Patent: May 10, 2016
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Lee Fader, Mathieu Parisien, Carl Thibeault, Louis Morency, Martin Duplessis, Clint James, Sébastien Morin, James Gillard
  • Cytomegalovirus inhibitor compounds
    Patent number: 9315499
    Abstract: Compounds of Formula (I) wherein n, m, R1, R2, R3, R4, R5 and R6 are defined herein, are useful for the treatment of cytomegalovirus disease and/or infection.
    Type: Grant
    Filed: April 3, 2013
    Date of Patent: April 19, 2016
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Lee Fader, Olivier Lepage, Murray Bailey, Pierre Louis Beaulieu, Francois Bilodeau, Rebekah J. Carson, André Giroux, Cédrickx Godbout, Benoît Moreau, Julie Naud, Mathieu Parisien, Martin Poirier, Maude Poirier, Simon Surprenant, Carl Thibeault
  • Inhibitors of cytomegalovirus
    Patent number: 9284310
    Abstract: Compounds of Formula (I) wherein n, R1, R1A, R2, R3, Y and Z are defined herein, are useful for the treatment of cytomegalovirus disease and/or infection.
    Type: Grant
    Filed: October 31, 2013
    Date of Patent: March 15, 2016
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Lee Fader, Francois Bilodeau, Mathieu Parisien, Maude Poirier, Cyrille Kuhn, Carl Thibeault, Thao Trinh
  • INHIBITORS OF CYTOMEGALOVIRUS
    Publication number: 20150315180
    Abstract: Compounds of Formula (I) wherein n, R1, R1A, R2, R3, Y and Z are defined herein, are useful for the treatment of cytomegalovirus disease and/or infection.
    Type: Application
    Filed: October 31, 2013
    Publication date: November 5, 2015
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Lee FADER, Francois BILODEAU, Mathieu PARISIEN, Maude POIRIER, Cyrille KUHN, Carl THIBEAULT, Thao TRINH
  • INHIBITORS OF CYTOMEGALOVIRUS
    Publication number: 20150284348
    Abstract: Compounds of Formula (I) wherein n, R1, R1A, R2, R4 and Z are defined herein, are useful for the treatment of cytomegalovirus disease and/or infection.
    Type: Application
    Filed: October 31, 2013
    Publication date: October 8, 2015
    Inventors: Lee Fader, Mathieu Parisien, Carl Thibeault, Louis Morency, Martin Duplessis, Clint James, Sébastien Morin, James Gillard
  • INHIBITORS OF CYTOMEGALOVIRUS
    Publication number: 20150274744
    Abstract: Compounds of Formula (I) wherein R1, R2, R3A, R3B, Y, Z1 and Z2 are defined herein, are useful for the treatment of cytomegalovirus disease and/or infection.
    Type: Application
    Filed: October 31, 2013
    Publication date: October 1, 2015
    Inventors: Carl THIBEAULT, Jean RANCOURT, Pierre L. BEAULIEU, Anne DECOR, Chantal GRAND-MAITRE, Cyille KUHN, Elisia VILLEMURE, Melissa LEBLANC, Jene-Eric LACOSTE, Benoit MOREAU, Eric JOLICOEUR, Simon SURPRENANT, Oliver HUCKE
  • 7-HYDROXY-INDOLINYL ANTAGONISTS OF P2Y1 RECEPTOR
    Publication number: 20150259286
    Abstract: The present invention provides compounds of Formula (I): Formula (I) as defined in the specification and compositions comprising any of such novel compounds. These compounds are antagonists of P2Y1 receptor which may be used medicaments.
    Type: Application
    Filed: July 30, 2013
    Publication date: September 17, 2015
    Inventors: Alexandre L'Heureux, Sheldon Hiebert, Carol Hu, Patrick Y.S. Lam, John Lloyd, Zulan Pi, Jennifer X. Qiao, Carl Thibeault, George O. Tora, Wu Yang, Yufeng Wang, Tammy C. Wang, Michael S. Bowsher, Ruel Rejean
  • Amino-heteroaryl 7-hydroxy-spiropiperidine indolinyl antagonists of P2Y1 receptor
    Patent number: 9120798
    Abstract: The present invention provides compounds of Formula (I): as defined in the specification and compositions comprising any of such novel compounds. These compounds are antagonists of P2Y1 receptor which may be used as medicaments.
    Type: Grant
    Filed: July 29, 2013
    Date of Patent: September 1, 2015
    Assignee: Bristol-Myers Squibb Company
    Inventors: Jennifer X. Qiao, Carol Hui Hu, Carl Thibeault
  • AMINO-HETEROARYL 7-HYDROXY-SPIROPIPERIDINE INDOLINYL ANTAGONISTS OF P2Y1 RECEPTOR
    Publication number: 20150197521
    Abstract: The present invention provides compounds of Formula (I): as defined in the specification and compositions comprising any of such novel compounds. These compounds are antagonists of P2Y1 receptor which may be used as medicaments.
    Type: Application
    Filed: July 29, 2013
    Publication date: July 16, 2015
    Inventors: Jennifer X. Qiao, Carol Hui Hu, Carl Thibeault
  • 7-HYDROXY-SPIROPIPIPERIDINE INDOLINYL ANTAGONISTS OF P2Y1 RECEPTOR
    Publication number: 20150166538
    Abstract: The present invention provides compounds of Formula (I): as defined in the specification and compositions comprising any of such novel compounds. These compounds are antagonists of P2Y1 receptor and may be used as medicaments in the treatment and/or prophylaxis of thromboembolic disorders.
    Type: Application
    Filed: July 30, 2013
    Publication date: June 18, 2015
    Inventors: Carl Thibeault, Charles G. Clark, Indawati DeLucca, Carol Hui Hu, Yoon Jeon, Patrick Y.S. Lam, Jennifer X. Qiao, Wu Yang, Yufeng Wang, Tammy C. Wang
  • CYTOMEGALOVIRUS INHIBITOR COMPOUNDS
    Publication number: 20150158861
    Abstract: Compounds of Formula (I) wherein n, m, R1, R2, R3, R4, R5 and R6 are defined herein, are useful for the treatment of cytomegalovirus disease and/or infection.
    Type: Application
    Filed: April 3, 2013
    Publication date: June 11, 2015
    Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
    Inventors: Lee Fader, Olivier Lepage, Murray Bailey, Pierre Louis Beaulieu, Francois Bilodeau, Rebekah J. Carson, André Giroux, Cédrickx Godbout, Benoît Moreau, Julie Naud, Mathieu Parisien, Martin Poirier, Maude Poirier, Simon Surprenant, Carl Thibeault
  • Inhibitors of human immunodeficiency virus replication
    Patent number: 8841331
    Abstract: Compounds of formula I: wherein a, R1, R2, R3, R4, R5 and R6 are defined herein, are useful as inhibitors of HIV replication.
    Type: Grant
    Filed: November 21, 2012
    Date of Patent: September 23, 2014
    Assignee: Gilead Sciences, Inc.
    Inventors: Christiane Yoakim, Murray D. Bailey, Francois Bilodeau, Rebekah Carson, Lee Fader, Stephen Kawai, Sebastien Morin, Carl Thibeault, Bruno Simoneau, Simon Surprenant, Youla S. Tsantrizos, Steven R. Laplante
  • PROCESS FOR THE PREPARATION OF AN HIV INTEGRASE INHIBITOR
    Publication number: 20140094609
    Abstract: The present invention is directed to an improved process for the preparation of Compounds of Formula (I), which are useful in the treatment of HIV infection. In particular, the present invention is directed to an improved process for the preparation of (2S)-2-tert-butoxy-2-(4-(2,3-dihydropyrano[4,3,2-de]quinolin-7-yl)-2-methylquinolin-3-yl)acetic acid, which is useful in the treatment of HIV infection.
    Type: Application
    Filed: October 2, 2013
    Publication date: April 3, 2014
    Inventors: Brandon H. Brown, Xiang Wang, Keith R. Fandrick, Joe Ju Gao, Nizar Haddad, Serge R. Landry, Wenjie Li, Zhi-Hui Lu, Bo Qu, Diana C. Reeves, Carl Thibeault, Yongda Zhang
  • Inhibitors of human immunodeficiency virus replication
    Patent number: 8338441
    Abstract: Compounds of formula I: wherein a, R1, R2, R3, R4, R5 and R6 are defined herein, are useful as inhibitors of HIV replication.
    Type: Grant
    Filed: May 11, 2010
    Date of Patent: December 25, 2012
    Assignee: Gilead Sciences, Inc.
    Inventors: Christiane Yoakim, Murray Bailey, Francois Bilodeau, Rebekah Carson, Lee Fader, Stephen Kawai, Sebastien Morin, Carl Thibeault, Bruno Simoneau, Simon Surprenant, Youla Tsantrizos, Steven Laplante
  • Heteroaryl compounds as P2Yreceptor inhibitors
    Patent number: 8273772
    Abstract: The present invention provides novel heteroaryl compounds and analogues thereof, which are selective inhibitors of the human P2Y1 receptor. The invention also provides for various pharmaceutical compositions of the same and methods for treating diseases responsive to modulation of P2Y1 receptor activity.
    Type: Grant
    Filed: November 17, 2009
    Date of Patent: September 25, 2012
    Assignee: Bristol-Myers Squibb Company
    Inventors: James C. Sutton, Zulan Pi, Rejean Ruel, Alexandre L'Heureux, Carl Thibeault, Patrick Y. S. Lam
  • INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION
    Publication number: 20100292227
    Abstract: Compounds of formula I: wherein a, R1, R2, R3, R4, R5 and R6 are defined herein, are useful as inhibitors of HIV replication.
    Type: Application
    Filed: May 11, 2010
    Publication date: November 18, 2010
    Applicant: BOEHRINGER INGLEHEIM INTERNATIONAL GMBH
    Inventors: CHRISTIANE YOAKIM, MURRAY BAILEY, FRANCOIS BILODEAU, REBEKAH CARSON, LEE FADER, STEPHEN KAWAI, SEBASTIEN MORIN, CARL THIBEAULT, BRUNO SIMONEAU, SIMON SURPRENANT, YOULA TSANTRIZOS, STEVEN LAPLANTE
  • C-linked cyclic antagonists of P2Yreceptor useful in the treatment of thrombotic conditions
    Patent number: 7700620
    Abstract: The present invention provides novel C-linked cyclic compounds and analogues of Formula (I): or a stereoisomer, tautomer, pharmaceutically acceptable salt or solvate form thereof, wherein the variables A, B, D and W are as defined herein. These compounds are selective inhibitors of the human P2Y1 receptor which can be used as medicaments.
    Type: Grant
    Filed: June 26, 2006
    Date of Patent: April 20, 2010
    Assignee: Bristol-Myers Squibb Company
    Inventors: James C. Sutton, Jennifer X. Qiao, Carl Thibeault, Rejean Ruel