Patents by Inventor Carl-Wilhelm E. Vogel

Carl-Wilhelm E. Vogel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • In vivo binding pair pretargeting
    Patent number: 5578289
    Abstract: A method for in-vivo targeting a functional moiety in a patient by administering a targeting moiety coupled to an affinity component, wherein the targeting moiety has affinity for binding sites in a target area, and administering a binding partner to the affinity component coupled to a functional moiety to localize the functional moiety in the target area. Preferably the targeting moiety is an antibody and the functional moiety is a radiometal when performing in vivo imaging or therapy. The affinity component may be a novel methotrexate analog.
    Type: Grant
    Filed: November 4, 1993
    Date of Patent: November 26, 1996
    Assignee: Akzo N.V.
    Inventors: Nicholas Pomato, Richard P. McCabe, Gregory A. Hawkins, Reinhard Bredehorst, Chong-Ho Kim, Carl-Wilhelm E. Vogel
  • Cytotoxic compositions
    Patent number: 4661347
    Abstract: A cytotoxic composition is described comprising a moiety having binding affinity to a surface structure of a cell and coupled to a moiety having activity as a structural subunit of C3/C5 convertase.
    Type: Grant
    Filed: March 7, 1985
    Date of Patent: April 28, 1987
    Assignee: Scripps Clinic
    Inventors: Hans J. Muller-Eberhard, Carl-Wilhelm E. Vogel