Patents by Inventor Carla De Faveri

Carla De Faveri has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL SALTS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF INFLAMMATORY DISORDERS
    Publication number: 20180007043
    Abstract: The present invention discloses salts of a Compound 1: useful in the prophylaxis and/or treatment of inflammatory conditions, autoimmune diseases, proliferative diseases, allergy, transplant rejection, diseases involving degradation and/or disruption of cartilage homeostasis, congenital cartilage malformations, and/or diseases associated with hypersecretion of IL6 or interferons.
    Type: Application
    Filed: July 10, 2017
    Publication date: January 4, 2018
    Inventors: Nicolas Luc SABOURAULT, Carla DE FAVERI, Ahmad SHEIKH
  • (?)-(2R,3S)-2-amino-3-hydroxy-3-pyridin-4-yl-1-pyrrolidin-1-yl-propan-1-one (L)-(+) tartrate salt, its method of production and use
    Patent number: 9540328
    Abstract: The present invention is directed to (?)-(2R,3S)-2-amino-3-hydroxy-3-pyridin-4-yl-1-pyrrolidin-1-yl-propan-1-one (L)-(+) tartrate salt, a pharmaceutical composition comprising said salt, a process for making said salt, and the use of said salt in the treatment of pain.
    Type: Grant
    Filed: December 21, 2015
    Date of Patent: January 10, 2017
    Assignee: ALLERGAN, INC.
    Inventors: Gyorgy F. Ambrus, Katherine C. Kurjan, Jacopo Zanon, Giovanna Libralon, Carla De Faveri
  • NOVEL SALTS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF INFLAMMATORY DISORDERS
    Publication number: 20160376269
    Abstract: The present invention discloses salts of a Compound 1: useful in the prophylaxis and/or treatment of inflammatory conditions, autoimmune diseases, proliferative diseases, allergy, transplant rejection, diseases involving degradation and/or disruption of cartilage homeostasis, congenital cartilage malformations, and/or diseases associated with hypersecretion of IL6 or interferons.
    Type: Application
    Filed: July 1, 2016
    Publication date: December 29, 2016
    Inventors: Nicolas Luc SABOURAULT, Carla DE FAVERI, Ahmad SHEIKH
  • (-)-(2R,3S)-2-AMINO-3-HYDROXY-3-PYRIDIN-4-YL-1-PYRROLIDIN-1-YL-PROPAN-1-ONE (L)-(+) TARTRATE SALT, ITS METHOD OF PRODUCTION AND USE
    Publication number: 20160347712
    Abstract: The present invention is directed to (?)-(2R,3S)-2-amino-3-hydroxy-3-pyridin-4-yl-1-pyrrolidin-1-yl-propan-1-one (L)-(+) tartrate salt, a pharmaceutical composition comprising said salt, a process for making said salt, and the use of said salt in the treatment of pain.
    Type: Application
    Filed: December 21, 2015
    Publication date: December 1, 2016
    Inventors: Gyorgy F. Ambrus, Katherine C. Kurjan, Jacopo Zanon, Giovanna Libralon, Carla De Faveri
  • Salts and pharmaceutical compositions thereof for the treatment of inflammatory disorders
    Patent number: 9382247
    Abstract: The present invention discloses salts of a Compound 1: useful in the prophylaxis and/or treatment of inflammatory conditions, autoimmune diseases, proliferative diseases, allergy, transplant rejection, diseases involving degradation and/or disruption of cartilage homeostasis, congenital cartilage malformations, and/or diseases associated with hypersecretion of IL6 or interferons.
    Type: Grant
    Filed: February 4, 2015
    Date of Patent: July 5, 2016
    Assignee: GALAPAGOS NV
    Inventors: Nicolas Luc Sabourault, Carla De Faveri, Ahmad Sheikh
  • (-)-(2R,3S)-2-amino-3-hydroxy-3-pyridin-4-yl-1-pyrrolidin-1-yl-propan-1-one (L)-(+) tartrate salt, its method of production and use
    Patent number: 9242935
    Abstract: The present invention is directed to (?)-(2R,3S)-2-amino-3-hydroxy-3-pyridin-4-yl-1-pyrrolidin-1-yl-propan-1-one (L)-(+)tartrate salt, a pharmaceutical composition comprising said salt, a process for making said salt, and the use of said salt in the treatment of pain.
    Type: Grant
    Filed: August 14, 2014
    Date of Patent: January 26, 2016
    Assignee: ALLERGAN, INC.
    Inventors: Gyorgy F. Ambrus, Katherine C. Kurjan, Jacopo Zanon, Giovanna Libralon, Carla De Faveri
  • NOVEL SALTS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF INFLAMMATORY DISORDERS
    Publication number: 20150225398
    Abstract: The present invention discloses salts of a Compound 1: useful in the prophylaxis and/or treatment of inflammatory conditions, autoimmune diseases, proliferative diseases, allergy, transplant rejection, diseases involving degradation and/or disruption of cartilage homeostasis, congenital cartilage malformations, and/or diseases associated with hypersecretion of IL6 or interferons.
    Type: Application
    Filed: February 4, 2015
    Publication date: August 13, 2015
    Inventors: Nicolas Luc SABOURAULT, Carla DE FAVERI, Ahmad SHEIKH
  • ( ) (2R,3S)-2-AMINO-3-HYDROXY-3-PYRIDIN-4-YL-1-PYRROLIDIN-1-YL-PROPAN-1-ONE (L)-(+) TARTRATE SALT, ITS METHOD OF PRODUCTION AND USE
    Publication number: 20150051253
    Abstract: The present invention is directed to (?)-(2R,3S)-2-amino-3-hydroxy-3-pyridin-4-yl-1-pyrrolidin-1-yl-propan-1-one (L)-(+)tartrate salt, a pharmaceutical composition comprising said salt, a process for making said salt, and the use of said salt in the treatment of pain.
    Type: Application
    Filed: August 14, 2014
    Publication date: February 19, 2015
    Inventors: Gyorgy F. Ambrus, Katherine C. Kurjan, Jacopo Zanon, Giovanna Libralon, Carla De Faveri
  • Methods for preparing ritodrine hydrochloride
    Patent number: 8912360
    Abstract: Methods for preparing Ritodrine hydrochloride are provided. Also provided is non-hygroscopic, crystalline, polymorphic Ritodrine hydrochloride of Form I.
    Type: Grant
    Filed: March 24, 2011
    Date of Patent: December 16, 2014
    Assignee: Lundbeck Pharmaceuticals Italy S.p.A.
    Inventors: Jacopo Zanon, Giovanna Libralon, Carla De Faveri, Florian Anton Martin Huber
  • PROCESS FOR RECOVERY OF NALMEFENE HYDROCHLORIDE
    Publication number: 20140296525
    Abstract: The present invention relates to an improved process for recovery of nalmefene hydrochloride [17-(cyclopropylmethyl)-4,5- alpha-epoxy-6-methylenemorphinan-3,14-diol hydrochloride] from an aqueous composition containing nalmefene and certain impurities.
    Type: Application
    Filed: December 6, 2012
    Publication date: October 2, 2014
    Inventors: Carla De Faveri, Mariano Stivanello
  • Process for recovery of nalmefene hydrochloride
    Patent number: 8841452
    Abstract: The present invention relates to an improved process for recovery of nalmefene hydrochloride[17-(cyclopropylmethyl)-4,5-alpha-epoxy-6-methylenemorphinan-3,14-diol hydrochloride] from an aqueous composition containing nalmefene and certain impurities.
    Type: Grant
    Filed: December 6, 2012
    Date of Patent: September 23, 2014
    Assignee: H. Lundbeck A/S
    Inventors: Carla De Faveri, Mariano Stivanello
  • Nalmefene hydrochloride dihydrate
    Patent number: 8754217
    Abstract: The present invention relates to the Nalmefene hydrochloride dihydrate, methods of manufacturing Nalmefene hydrochloride dihydrate, a pharmaceutical composition comprising Nalmefene hydrochloride dihydrate and a method of treatment comprising administering Nalmefene hydrochloride dihydrate.
    Type: Grant
    Filed: June 25, 2013
    Date of Patent: June 17, 2014
    Assignee: H. Lundbeck A/S
    Inventors: Heidi Lopez de Diego, Carla De Faveri, Florian Anton Martin Huber
  • METHOD FOR THE MANUFACTURING OF NALTREXONE
    Publication number: 20140155608
    Abstract: The present invention relates to a new process for producing naltrexone [17-(cyclopropylmethyl)-4,5?-epoxy-3,14-dihydroxy-morphinan-6-one] from noroxymorphone [4,5-?-epoxy-3,14-dihydroxy-morphinan-6-one] by alkylation with a cyclopropylmethyl halide.
    Type: Application
    Filed: May 2, 2013
    Publication date: June 5, 2014
    Inventors: Carla De Faveri, Mariano Stivanello, Florian Anton Martin Huber
  • NALMEFENE HYDROCHLORIDE DIHYDRATE
    Publication number: 20130338365
    Abstract: The present invention relates to the Nalmefene hydrochloride dihydrate, methods of manufacturing Nalmefene hydrochloride dihydrate, a pharmaceutical composition comprising Nalmefene hydrochloride dihydrate and a method of treatment comprising administering Nalmefene hydrochloride dehydrate.
    Type: Application
    Filed: June 25, 2013
    Publication date: December 19, 2013
    Inventors: Heidi Lopez de DIEGO, Carla de FAVERI, Florian Anton Martin HUBER
  • Preparation of nalmefene hydrochloride from naltrexone
    Patent number: 8598352
    Abstract: Method for producing nalmefene hydrochloride from naltrexone, which method is particular well adapted for large-scale industrial application, and has been found to be efficient, to give a high yield and to afford highly pure nalmefene hydrochloride salt.
    Type: Grant
    Filed: May 21, 2010
    Date of Patent: December 3, 2013
    Assignee: H. Lundbeck A/S
    Inventors: Carla De Faveri, Mauro Casarin, Michele Brusegan
  • Method for the manufacturing of naltrexone
    Patent number: 8580963
    Abstract: The present invention relates to an improved process for producing naltrexone[17-(cyclopropylmethyl)-4,5?-epoxy-3,14-dihydroxy-morphinan-6-one] from noroxymorphone[4,5-?-epoxy-3,14-dihydroxy-morphinan-6-one] by alkylation with a cyclopropylmethyl halide.
    Type: Grant
    Filed: November 2, 2011
    Date of Patent: November 12, 2013
    Assignee: H. Lundbeck A/S
    Inventors: Carla De Faveri, Florian Anton Martin Huber, Mariano Stivanello
  • Nalmefene hydrochloride dihydrate
    Patent number: 8530495
    Abstract: The present invention relates to the Nalmefene hydrochloride dihydrate, methods of manufacturing Nalmefene hydrochloride dihydrate, a pharmaceutical composition comprising Nalmefene hydrochloride dihydrate and a method of treatment comprising administering Nalmefene hydrochloride dihydrate.
    Type: Grant
    Filed: December 4, 2009
    Date of Patent: September 10, 2013
    Assignees: H. Lundbeck A/S, Bioei Therapies Corp
    Inventors: Heidi Lopez de Diego, Carla de Faveri, Florian Anton Martin Huber
  • Process for the manufacture of memantine and intermediate product
    Patent number: 8436209
    Abstract: The present invention relates to a process for manufacturing N-Formyl-1-amino-3,5-dimethyladamantane, an intermediate product in the overall process of producing 1-Amino-3,5-dimethyladamantane hydrochloride (Memantine). Therein, the process comprises the following steps: (a) reacting 1,3-dimethyladamantane with an acid mixture comprising concentrated sulfuric acid and concentrated nitric acid, wherein 1 to 6 volume parts of sulfuric acid (measured in ml) are used per weight part of 1,3-dimethyladamantane (measured in g); (b) reacting the solution from step (a) with an amount of formamide varying from 1 to 5 molar equivalents per mole of deprotonated 1,3-dimethyladamantane from step (a) to obtain N-Formyl-1-amino-3,5-dimethyladamantane. In step (b), the molar ratio of total acid, i.e. the molar amount of sulfuric acid and the molar amount of nitric acid taken together versus the molar amount of formamide is at least 1.5 and that the temperature is at least 50° C.
    Type: Grant
    Filed: March 19, 2009
    Date of Patent: May 7, 2013
    Assignee: Merz Pharma GmbH & Co. KGaA
    Inventors: Florian Anton Martin Huber, Giorgio Gallo, Carla De Faveri
  • PREPARATION OF NALMEFENE HYDROCHLORIDE FROM NALTREXONE
    Publication number: 20120123123
    Abstract: Method for producing nalmefene hydrochloride from naltrexone, which method is particular well adapted for large-scale industrial application, and has been found to be efficient, to give a high yield and to afford highly pure nalmefene hydrochloride salt.
    Type: Application
    Filed: May 21, 2010
    Publication date: May 17, 2012
    Applicant: H. Lundbeck A/S
    Inventors: Carla De Faveri, Mauro Casarin, Michele Brussegan
  • METHOD FOR THE MANUFACTURING OF NALTREXONE
    Publication number: 20120116085
    Abstract: The present invention relates to an improved process for producing naltrexone[17-(cyclopropylmethyl)-4,5?-epoxy-3,14-dihydroxy-morphinan-6-one] from noroxymorphone[4,5-?-epoxy-3,14-dihydroxy-morphinan-6-one] by alkylation with a cyclopropylmethyl halide.
    Type: Application
    Filed: November 2, 2011
    Publication date: May 10, 2012
    Applicant: H. Lundbeck A/S
    Inventors: Carla De Faveri, Florian Anton Martin Huber, Mariano Stivanello