Patents by Inventor Carla Prllrgrino

Carla Prllrgrino has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for the identification of novel ligands for the g protein-coupled receptor (gpcr) 192
    Publication number: 20060078498
    Abstract: The present invention relates to methods for the identification and characterization of polypeptides with ligand activity for the G protein coupled receptor (GPCR) 192. The invention encompasses the use of the ligands in combination with the receptor for the development of assays/kits for the identification of molecules that affect the ability of the ligand to interact with the receptor. In addition, the invention relates to molecules affecting the expression of the ligands (e.g., antisense DNA, ribozymes, antibodies) that may modulate the activity of the receptor. The invention also encompasses the use of the ligands and their derivatives, molecules affecting ligand expression, and compounds that modulate receptor activity for the treatment of disorders involving GPCR 192, such as those of the central nervous system, metabolic disorders (e.g., pancreatic disorders), gastrointestinal disorders, immune disorders, and cancer.
    Type: Application
    Filed: March 28, 2003
    Publication date: April 13, 2006
    Applicant: Bayer Pharmaceuticals Corporatioh
    Inventors: Thomas Buckholz, Mark Vandenberg, Carla Prllrgrino, Stefan Heitmeier, Ian Taylor, Richard Gedrich