Patents by Inventor Carleton Sage

Carleton Sage has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fused-aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto
    Publication number: 20070082874
    Abstract: The present invention relates to certain fused aryl and heteroaryl derivatives of Formula (I) that are modulators of metabolism. Accordingly, compounds of the present invention are useful in the prophylaxis or treatment of metabolic disorders and complications thereof, such as, diabetes and obesity.
    Type: Application
    Filed: November 20, 2006
    Publication date: April 12, 2007
    Applicant: Arena Pharmaceuticlas, Inc.
    Inventors: Robert Jones, Graeme Semple, Yifeng Xiong, Young-Jun Shin, Albert Ren, Imelda Calderon, Beatriz Fioravanti, Jin Sun Karoline Choi, Carleton Sage
  • Fused-aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto
    Publication number: 20070072844
    Abstract: The present invention relates to certain fused aryl and heteroaryl derivatives of Formula (I) that are modulators of metabolism. Accordingly, compounds of the present invention are useful in the prophylaxis or treatment of metabolic disorders and complications thereof, such as, diabetes and obesity.
    Type: Application
    Filed: November 20, 2006
    Publication date: March 29, 2007
    Applicant: Arena Pharmaceuticals, Inc.
    Inventors: Robert Jones, Graeme Semple, Yifeng Xiong, Young-Jun Shin, Albert Ren, Imelda Calderon, Beatriz Fioravanti, Jin Choi, Carleton Sage
  • Fused-aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto
    Publication number: 20060142262
    Abstract: The present invention relates to certain fused aryl and heteroaryl derivatives of Formula (I) that are modulators of metabolism. Accordingly, compounds of the present invention are useful in the prophylaxis or treatment of metabolic disorders and complications thereof, such as, diabetes and obesity.
    Type: Application
    Filed: February 16, 2006
    Publication date: June 29, 2006
    Inventors: Robert Jones, Graeme Semple, Yifeng Xiong, Young-Jun Shin, Albert Ren, Imelda Calderon, Beatriz Fioravanti, Carleton Sage
  • Fused-aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto
    Publication number: 20050059650
    Abstract: The present invention relates to certain fused aryl and heteroaryl derivatives of Formula (I) that are modulators of metabolism. Accordingly, compounds of the present invention are useful in the prophylaxis or treatment of metabolic disorders and complications thereof, such as, diabetes and obesity.
    Type: Application
    Filed: July 13, 2004
    Publication date: March 17, 2005
    Inventors: Robert Jones, Graeme Semple, Yifeng Xiong, Young-Jun Shin, Albert Ren, Imelda Calderon, Beatriz Fioravanti, Jin Sun Karoline Choi, Carleton Sage
  • Regional intestinal permeability model
    Publication number: 20040180322
    Abstract: Permeability models and methods for creating the models are disclosed. The models include receiving as an input in vitro permeability and structure data for a particular compound. Then the data is mapped to at least one permeability. In some models the data is mapped to a plurality of permeabilities, each associated with a specific region in a mammalian GI tract. Some models may take into consideration solubility, permeability and at least one molecular descriptor associated with the compound of interest.
    Type: Application
    Filed: June 5, 2003
    Publication date: September 16, 2004
    Inventors: George M. Grass, Glen D. Leesman, Daniel A. Norris, Patrick J. Sinko, Jehangir Athwal, Carleton Sage, Troy Bremer, Kevin Holme, Yong-Hee Lee, Kyoung Lee
  • System and method for predicting adme/tox characteristics of a compound
    Publication number: 20040009536
    Abstract: A method for developing a predictive model of a chemical compound property. The method includes obtaining at least one descriptor from structural data for each of a plurality of compounds. At least one chemical compound property is obtained for each of the plurality of compounds. The predictive model is developed by mapping the at least one descriptor to the chemical compound property. The chemical compound property may be an ADME property. The ADME property may be absorption. The chemical compound property may also be an toxicity property.
    Type: Application
    Filed: May 30, 2003
    Publication date: January 15, 2004
    Inventors: George Grass, Glen D Leesman, Daniel Norris, Patrick Sinko, Jehangir Athwal, Carleton Sage, Troy Bremer, Kevin Holme