Abstract: The present invention provides the use of highly homogeneous serum albumin as a chiral selector, preferably immobilised, such as in enantioselective chromatography. The present invention also provides an enantioselective chromatography column comprising, as the immobilised phase, highly homogeneous serum albumin. The present invention also provides a process for selecting an enantiomer of a chiral compound, comprising the steps of exposing a mixture of enantiomers of the compound to highly homogeneous serum albumin for a period to allow selective binding of one enantiomer to the albumin; and separating the relatively unbound enantiomer from the albumin.