Patents by Inventor Carlo Bifulco

Carlo Bifulco has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200143542
    Abstract: A system and method of displaying of multiple simultaneous views of a same region of a biological tissue sample. Logical instructions are executed by a processor to perform operations such as receiving a plurality of images of the biological tissue sample, converting the plurality of images to a common reference frame based on the individual metadata of each image, and arranging the plurality of images into a display pattern for simultaneous viewing of different aspects of the imaged biological tissue sample on a display screen. The plurality of images is produced by preprocessing images of the biological tissue sample. Each image shows a view mode of a same region of the biological tissue sample, and each image contains metadata that describe spatial orientation, such as the translation, rotation, and magnification, of the image to bring the plurality of images to a common view.
    Type: Application
    Filed: December 21, 2019
    Publication date: May 7, 2020
    Applicants: Ventana Medical Systems, Inc., Providence Health & Services - Oregon
    Inventors: Michael Barnes, Carlo Bifulco, Christophe Chefd'hotel, Ting Chen, Alisa Tubbs
  • Patent number: 10552960
    Abstract: A system and method of displaying of multiple simultaneous views of a same region of a biological tissue sample. Logical instructions are executed by a processor to perform operations such as receiving a plurality of images of the biological tissue sample, converting the plurality of images to a common reference frame based on the individual metadata of each image, and arranging the plurality of images into a display pattern for simultaneous viewing of different aspects of the imaged biological tissue sample on a display screen. The plurality of images is produced by preprocessing images of the biological tissue sample. Each image shows a view mode of a same region of the biological tissue sample, and each image contains metadata that describe spatial orientation, such as the translation, rotation, and magnification, of the image to bring the plurality of images to a common view.
    Type: Grant
    Filed: March 2, 2018
    Date of Patent: February 4, 2020
    Assignees: Ventana Medical Systems, Inc., Providence Health & Services—Oregon
    Inventors: Michael Barnes, Carlo Bifulco, Christophe Chefd'hotel, Ting Chen, Alisa Tubbs
  • Patent number: 10275880
    Abstract: Systems and methods for automatic FOV selection in immunoscore computation that involve reading images for individual markers from an unmixed multiplex slide or single stain slides, and computing the tissue region mask from the individual marker image. The heat map of each marker is determined by applying the low pass filter on the individual marker image channel and selecting the top K highest intensity regions from the heat map as the candidate FOVs for each marker. The candidate FOVs from the individual marker images are merged together in the same coordinate system by either adding all of the FOVs together or by only adding the FOVs from the selected marker images depending on the user's choice, and registering all the individual marker images to a common coordinate system and transferring the FOVs back to the original images.
    Type: Grant
    Filed: November 30, 2016
    Date of Patent: April 30, 2019
    Assignees: Ventana Medical Systems, Inc., Providence Health & Services—Oregon
    Inventors: Michael Barnes, Carlo Bifulco, Ting Chen, Alisa Tubbs
  • Publication number: 20180322632
    Abstract: A system and method of displaying of multiple simultaneous views of a same region of a biological tissue sample. Logical instructions are executed by a processor to perform operations such as receiving a plurality of images of the biological tissue sample, converting the plurality of images to a common reference frame based on the individual metadata of each image, and arranging the plurality of images into a display pattern for simultaneous viewing of different aspects of the imaged biological tissue sample on a display screen. The plurality of images is produced by preprocessing images of the biological tissue sample. Each image shows a view mode of a same region of the biological tissue sample, and each image contains metadata that describe spatial orientation, such as the translation, rotation, and magnification, of the image to bring the plurality of images to a common view.
    Type: Application
    Filed: March 2, 2018
    Publication date: November 8, 2018
    Inventors: Michael Barnes, Carlo Bifulco, Christophe Chefd'hotel, Ting Chen, Alisa Tubbs
  • Publication number: 20170154420
    Abstract: Systems and methods for automatic FOV selection in immunoscore computation that involve reading images for individual markers from an unmixed multiplex slide or single stain slides, and computing the tissue region mask from the individual marker image. The heat map of each marker is determined by applying the low pass filter on the individual marker image channel and selecting the top K highest intensity regions from the heat map as the candidate FOVs for each marker. The candidate FOVs from the individual marker images are merged together in the same coordinate system by either adding all of the FOVs together or by only adding the FOVs from the selected marker images depending on the user's choice, and registering all the individual marker images to a common coordinate system and transferring the FOVs back to the original images.
    Type: Application
    Filed: November 30, 2016
    Publication date: June 1, 2017
    Inventors: Michael Barnes, Carlo Bifulco, Ting Chen, Alisa Tubbs