Patents by Inventor Carlo D. Montemagno

Carlo D. Montemagno has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11981948
    Abstract: Described herein are engineered organelles comprising multi-component proteins from different species incorporated into a membrane structure with interior and exterior aspects. In one embodiment the artificial organelle incorporates one or more protein complexes that absorb optical energy and catalyze electron transfer in biochemical reactions that can be used to reduce NAD+ to NADH or analogues thereof.
    Type: Grant
    Filed: November 2, 2022
    Date of Patent: May 14, 2024
    Assignee: Ensovi, Inc.
    Inventors: Kyle A Minor, Carlo D. Montemagno, David W. Wendell
  • Publication number: 20240068003
    Abstract: Described herein are engineered organelles comprising multi-component proteins from different species incorporated into a membrane structure with interior and exterior aspects. In one embodiment the artificial organelle incorporates one or more protein complexes that absorb optical energy and catalyze electron transfer in biochemical reactions that can be used to reduce NAD+ to NADH or analogues thereof.
    Type: Application
    Filed: September 21, 2023
    Publication date: February 29, 2024
    Inventors: Kyle A. Minor, Carlo D. Montemagno, David W. Wendell
  • Publication number: 20230212632
    Abstract: Described herein are engineered organelles comprising multi-component proteins from different species incorporated into a membrane structure with interior and exterior aspects. In one embodiment the artificial organelle incorporates one or more protein complexes that absorb optical energy and catalyze electron transfer in biochemical reactions that can be used to reduce NAD+ to NADH or analogues thereof.
    Type: Application
    Filed: November 2, 2022
    Publication date: July 6, 2023
    Inventors: Kyle A. Minor, Carlo D. Montemagno, David W. Wendell
  • Patent number: 11535880
    Abstract: Described herein are engineered organelles comprising multi-component proteins from different species incorporated into a membrane structure with interior and exterior aspects. In one embodiment the artificial organelle incorporates one or more protein complexes that absorb optical energy and catalyze electron transfer in biochemical reactions that can be used to reduce NAD+ to NADH or analogues thereof.
    Type: Grant
    Filed: January 7, 2021
    Date of Patent: December 27, 2022
    Assignee: ENSOVI, INC.
    Inventors: Kyle A. Minor, Carlo D. Montemagno, David W. Wendell
  • Publication number: 20210214762
    Abstract: Described herein are engineered organelles comprising multi-component proteins from different species incorporated into a membrane structure with interior and exterior aspects. In one embodiment the artificial organelle incorporates one or more protein complexes that absorb optical energy and catalyze electron transfer in biochemical reactions that can be used to reduce NAD+ to NADH or analogues thereof.
    Type: Application
    Filed: January 7, 2021
    Publication date: July 15, 2021
    Inventors: Kyle A. Minor, Carlo D. Montemagno, David W. Wendell
  • Patent number: 9440195
    Abstract: The present invention relates to a method for producing man-made devices which have the properties and functions of biological membranes and membrane proteins, and to the structure of such devices. Briefly, in one aspect of the invention, natural or genetically engineered proteins are incorporated into a polymeric vesicle that is conjugated to a thread to form a vesicle-thread conjugate. The engineered protein is preferably a transmembrane protein embedded in the wall of the polymeric vesicle. The vesicle-thread conjugate is then formed into a membrane or thin fabric having a wide variety of inherent functionality, including the ability to selectively transport and/or filter compounds between fluids. By selecting proteins with specific properties, membranes can be fabricated with a defined functionality including molecular scale addressability via directed electrostatic, electromagnetic, and chemical forces.
    Type: Grant
    Filed: October 6, 2009
    Date of Patent: September 13, 2016
    Assignee: Applied Biomimetic A/S
    Inventor: Carlo D. Montemagno
  • Publication number: 20110259815
    Abstract: The present invention relates to a method for producing man-made devices which have the properties and functions of biological membranes and membrane proteins, and to the structure of such devices. Briefly, in one aspect of the invention, natural or genetically engineered proteins are incorporated into a polymeric vesicle that is conjugated to a thread to form a vesicle-thread conjugate. The engineered protein is preferably a transmembrane protein embedded in the wall of the polymeric vesicle. The vesicle-thread conjugate is then formed into a membrane or thin fabric having a wide variety of inherent functionality, including the ability to selectively transport and/or filter compounds between fluids. By selecting proteins with specific properties, membranes can be fabricated with a defined functionality including molecular scale addressability via directed electrostatic, electromagnetic, and chemical forces.
    Type: Application
    Filed: October 6, 2009
    Publication date: October 27, 2011
    Inventor: Carlo D. Montemagno
  • Patent number: 7600378
    Abstract: Movement of a gel structure is propagated by successively applying external stimuli to cause volume phase transition in the gel structure by alternately causing the gel structure to collapse and swell to move the center of mass of the gel structure in the direction of successive stimuli application. The movement is mediated by confining structure for the gel and anchoring the starting side of the gel in the swelling cycle.
    Type: Grant
    Filed: June 27, 2005
    Date of Patent: October 13, 2009
    Assignee: Cornell Research Foundation, Inc.
    Inventors: Lilit L. Yeghiazarian, Ulrich Wiesner, Carlo D. Montemagno
  • Patent number: 7313917
    Abstract: Movement of a gel structure is propagated by successively applying external stimuli to cause volume phase transition in the gel structure by alternately causing the gel structure to collapse and swell to move the center of mass of the gel structure in the direction of successive stimuli application. The movement is mediated by confining structure for the gel and anchoring—the starting side of the gel in the swelling cycle.
    Type: Grant
    Filed: July 1, 2004
    Date of Patent: January 1, 2008
    Assignee: Cornell Research Foundation, Inc.
    Inventors: Lilit L. Yeghiazarian, Ulrich Wiesner, Carlo D. Montemagno
  • Patent number: 7208089
    Abstract: Biological membrane proteins are incorporated into a co-polymer matrix to produce membranes with a wide variety of functionalities. In one form of the invention, a composite membrane incorporates two different proteins which cooperate to produce electricity from light. In another form, water transport proteins are embedded in a membrane to enable water purification.
    Type: Grant
    Filed: July 28, 2003
    Date of Patent: April 24, 2007
    Assignee: MT Technologies, Inc.
    Inventors: Carlo D. Montemagno, Jacob J. Schmidt, Steven P. Tozzi
  • Publication number: 20040110199
    Abstract: A microfluidic affinity system is designed to recognize, capture and separate target analytes from input solutions. This microfluidic affinity system employs fluidic channels fabricated by silicon-based lithography in a silicon substrate. The fluidic channels are patterned and replicated in a substrate, preferably polydimethylsiloxane, PDMS, by pattern transfer from a silicon wafer mold with reversed patterns fabricated by lithography. A novel three-step covalent binding method for surface modification employs the following steps to covalently immobilize an affinity ligand on the substrate: 1) a plasma treatment; 2) a silanization treatment; and 3) a crosslinking treatment.
    Type: Application
    Filed: August 28, 2003
    Publication date: June 10, 2004
    Inventors: Carlo D. Montemagno, Elsa I. Chang
  • Publication number: 20040101819
    Abstract: Cultured muscle tissue used as actuators in microelectromechanical systems (MEMS) for mechanical and electrical power generation can either be dissected or cultured from myoblasts and grown in situ. The MEMS is fabricated using conventional techniques (surface or bulk micromachining) and incorporating surface modification techniques and/or anchor structures to favor muscle attachment followed by post-processing to assemble dissected muscle tissue or grow the self-assembling muscle tissue at the desired sites. Initial post processing is done to incorporate PZT devices for energy conversion. Additional post-processing is then done for muscle tissue self-assembling; that includes coating the MEMS with polymers that will either repel or favor the muscle growth, and the culturing on the muscle tissue starting from myoblasts. The system is fueled by adding glucose to the medium in which it is contained.
    Type: Application
    Filed: August 7, 2003
    Publication date: May 27, 2004
    Applicant: MT Technologies, Inc.
    Inventors: Carlo D. Montemagno, Hercules P. Neves
  • Publication number: 20040049230
    Abstract: Biological membrane proteins are incorporated into a co-polymer matrix to produce membranes with a wide variety of functionalities. In one form of the invention, a composite membrane incorporates two different proteins which cooperate to produce electricity from light. In another form, water transport proteins are embedded in a membrane to enable water purification.
    Type: Application
    Filed: July 28, 2003
    Publication date: March 11, 2004
    Applicant: MT Technologies, Inc.
    Inventors: Carlo D. Montemagno, Jacob J. Schmidt, Steven P. Tozzi
  • Patent number: 6686299
    Abstract: A nanosyringe is constructed using micro fabrication and nano fabrication techniques on a silicon substrate. The nanosyringe includes a membrane of silicon carbide. The position and operation of individual nanosyringes, arranged in an array of nanosyringes, can be independently controlled. A nanosyringe array can inject or extract a fluid from one or more cells or other structures. Microfluidic structures coupled to the nanosyringe allow external pumping or extraction. A cell matrix or organelles of individual cells can be non-destructively sampled in real time.
    Type: Grant
    Filed: June 21, 2002
    Date of Patent: February 3, 2004
    Inventors: Carlo D. Montemagno, Hercules Neves
  • Publication number: 20030023149
    Abstract: A system and method for detecting microorganisms and abiotic or biotic contaminants in fluids, including food and potable and environmental waters. Various embodiments of the system include a capillary transport element and a microsensor element. The capillary transport element isolates and purifies the targeted substance. The microsensor element includes a channel with electrodes for detecting dielectric properties of the targeted substance. Both the transport element and the microsensor may be fabricated using micromachining or nanofabrication techniques. In one embodiment, an output of the transport element is coupled to the input of a microsensor. The targeted substance can be retained in a storage vessel for further analysis. The system may be integrated into a handheld device using disposable cartridges for detecting different microorganisms or contaminants.
    Type: Application
    Filed: July 1, 2002
    Publication date: January 30, 2003
    Inventors: Carlo D. Montemagno, Hercules Neves
  • Publication number: 20030015807
    Abstract: A nanosyringe is constructed using micro fabrication and nano fabrication techniques on a silicon substrate. The nanosyringe includes a membrane of silicon carbide. The position and operation of individual nanosyringes, arranged in an array of nanosyringes, can be independently controlled. A nanosyringe array can inject or extract a fluid from one or more cells or other structures. Microfluidic structures coupled to the nanosyringe allow external pumping or extraction. A cell matrix or organelles of individual cells can be non-destructively sampled in real time.
    Type: Application
    Filed: June 21, 2002
    Publication date: January 23, 2003
    Inventors: Carlo D. Montemagno, Hercules Neves
  • Patent number: 5126050
    Abstract: A periodic multistage process which minimizes fugitive pollutant emissions has been developed for the removal and destruction of volatile, semi-volatile, and non-volatile organic contaminants from either water, wastewater, or spent granular activated carbon. This invention relates to methods, materials, and systems for treating these contaminants by a process and devices which uniquely combine granular activated carbon adsorption and desorption with biological treatment. The process and devices extend existing treatment systems by: (1) providing biofilm growth in a Sequencing Batch Biofilm Reactor on gas permeable membrane which uses oxygen for the supply of the electron acceptor and other organics (e.g.
    Type: Grant
    Filed: May 10, 1990
    Date of Patent: June 30, 1992
    Assignee: SBR Technologies, Inc.
    Inventors: Robert L. Irvine, Lloyd H. Ketchum, Jr., Peter A. Wilderer, Carlo D. Montemagno