Patents by Inventor Carlo Giani

Carlo Giani has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Glucose- and sophorose-lipids, a process for their preparation and their use
    Patent number: 5767255
    Abstract: The present invention relates to glucose- and sophorose-lipids of the formula I ##STR1## in which R.sup.4 is --OH or a group of the formula II, ##STR2## n is an integer from 2 to 26, R.sup.1 and R.sup.2 are, independently of one another, H or ##STR3## R.sup.3 is H or --OH in the case where R.sup.4 is --OH, and is H or --OH or a group of the formula III, ##STR4## in the case where R.sup.4 is a group of the formula II, to a process for obtaining them by fermentation, and to their use as surfactants.
    Type: Grant
    Filed: May 20, 1996
    Date of Patent: June 16, 1998
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Dieter Wullbrandt, Carlo Giani, Andreas Brakemeier, Siegmund Lang, Fritz Wagner
  • Pseudomonas aeruginosa and its use in a process for the biotechnological preparation of L-rhamnose
    Patent number: 5658793
    Abstract: Bacterial strains are capable of the formation of rhamnolipids, which they generate in the culture solution. If bacteria of the type Pseudomonas aeruginosa are employed for the fermentation, these microorganisms synthesize rhamnolipids in a concentration of 70-120 g/l of culture solution. The L-rhamnose can be recovered directly from the culture solution by hydrolysis of the rhamnolipids, i.e. without a complicated separation of the cell material and without isolation of the rhamnolipids before hydrolysis.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: August 19, 1997
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Carlo Giani, Dieter Wullbrandt, Reinhardt Rothert, Johannes Meiwes
  • .alpha.-l-rhamnosidase for obtaining rhamnose, a process for its preparation and its use
    Patent number: 5641659
    Abstract: The invention relates to .alpha.-L-rhamnosidase, which catalyzes the cleavage of the bond between terminal rhamnose and the aglycone of rhamnose-containing glycosides, a process for preparing it by biotechnological means, and its use for preparing L(+)-rhamnose (6-deoxy-L-mannose).
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: June 24, 1997
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Johannes Meiwes, Dieter Wullbrandt, Carlo Giani
  • Pseudomonas aeruginosa and its use in a process for the biotechnological preparation of L-rhamnose
    Patent number: 5501966
    Abstract: Pseudomonas aeruginosa and its use in a process for the biotechnological production of L-rhamnoseBacterial strains are capable of the formation of rhamnolipids, which they generate in the culture solution. If bacteria of the type Pseudomonas aeruginosa are employed for the fermentation, these microorganisms synthesize rhamnolipids in a concentration of 70-120 g/l of culture solution. The L-rhamnose can be recovered directly from the culture solution by hydrolysis of the rhamnolipids, i.e. without a complicated separation of the cell material and without isolation of the rhamnolipids before hydrolysis.
    Type: Grant
    Filed: January 19, 1995
    Date of Patent: March 26, 1996
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Carlo Giani, Dieter Wullbrandt, Reinhardt Rothert, Johannes Meiwes
  • .alpha.-L-Rhamnosidase for obtaining rhamnose, a process for its preparation and its use
    Patent number: 5468625
    Abstract: The invention relates to .alpha.-L-rhamnosidase, which catalyzes the cleavage of the bond between terminal rhamnose and the aglycone of rhamnose-containing glycosides, a process for preparing it by biotechnological means, and its use for preparing L(+)-rhamnose (6-deoxy-L-mannose).
    Type: Grant
    Filed: November 24, 1993
    Date of Patent: November 21, 1995
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Johannes Meiwes, Dieter Wullbrandt, Carlo Giani
  • Streptomyces parvullus DSM 3816
    Patent number: 5158888
    Abstract: Streptomyces parvullus, DSM 3816, produces on aerobic fermentation new antibiotics which are distinguished by antimicrobial activity even after derivatization.
    Type: Grant
    Filed: February 19, 1992
    Date of Patent: October 27, 1992
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Peter Hammann, Susanne Grabley, Hartmut Voelskow, Burkhard Sachse, Wolfgang Raether, Carlo Giani, Gerhard Seibert
  • Streptenols from streptomycetes, and the preparation and use thereof
    Patent number: 5118882
    Abstract: Novel streptenols with pharmacological activity, in particular with HMG-CoA-reductase inhibiting activity, can be isolated from the nutrient broth of streptomycetes. These compounds can also be used as synthesis unit for the production of mevilonin analogues.
    Type: Grant
    Filed: February 22, 1990
    Date of Patent: June 2, 1992
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Axel Zeeck, Susanne Grabley, Joachim Wink, Peter Hammann, Carlo Giani, Pia Kricke-Helling
  • Angucyclinones from Streptomycetes, a process for the preparation thereof, and the use thereof
    Patent number: 5100921
    Abstract: New angucyclinones with a therapeutic action can be prepared with the aid of a strain of the genus Streptomyces.
    Type: Grant
    Filed: April 25, 1989
    Date of Patent: March 31, 1992
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Susanne Grabley, Joachim Wink, Carlo Giani, Gerhard Seibert, Wolfgang Raether, Susanne Dobreff, Axel Zeeck
  • Elaiophyline derivatives, compositions containing them and the use thereof as anthelmintic agents
    Patent number: 5011827
    Abstract: The invention relates to elaiophyline derivatives of the formula I ##STR1## in which R.sup.1 and R.sup.1' are identical or different and represent a radical of the formula II/or III ##STR2## in which R.sup.2, R.sup.3, R.sup.4, R.sup.5 and R.sup.7 have the meanings given. The invention furthermore relates to a process for the preparation of these elaiophyline derivatives and also the use of the lattere as medicaments, in particular as anthelmintically acting medicaments.
    Type: Grant
    Filed: October 28, 1988
    Date of Patent: April 30, 1991
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Gerhard Kretzschmar, Dieter Duwel, Susanne Grabley, Peter Hammann, Gerhard Seibert, Hartmut Voelskow, Carlo Giani
  • Angucyclinones from streptomycetes, a process for the preparation thereof, and the use thereof
    Patent number: 4945108
    Abstract: New angucyclinones with a therapeutic action can be prepared with the aid of a strain of the genus Streptomyces.
    Type: Grant
    Filed: April 24, 1989
    Date of Patent: July 31, 1990
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Susanne Grabley, Joachim Wink, Carlo Giani, Gerhard Seibert, Wolfgang Raether, Susanne Dobreff, Axel Zeeck
  • Amycin and its derivatives, a process for their preparation, and their use
    Patent number: 4914216
    Abstract: Streptomyces parvullus, DSM 3816, produces on aerobic fermentation new antibiotics which are distinguished by antimicrobial activity even after derivatization.
    Type: Grant
    Filed: December 22, 1987
    Date of Patent: April 3, 1990
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Peter Hammann, Susanne Grabley, Hartmut Voelskow, Burkhard Sachse, Wolfgang Raether, Carlo Giani, Gerhard Seibert