Abstract: The present technology aims at providing a novel type of drug for treating a subject suffering from cancer. Specifically, the technology provides polypeptides comprising at least four immunoglobulin single variable domains (ISVDs), characterized in that one ISVD binds to TCR and at least two ISVDs bind to GPC3. The present technology also provides nucleic acids, vectors and compositions.

Abstract: A sorting apparatus is described and which includes an inspection station; a multiplicity of electromagnetic radiation emitters and detectors; an optical filter which is positioned in front of the electromagnetic radiation detectors, and which passes electromagnetic radiation having a given polarization; an ejector assembly positioned downstream from the inspection station for removing defective objects of interest which are identified; and a computer/controller for selectively energizing the electromagnetic radiation emitter, and detector, and rendering the ejector assembly operational to remove defective objects of interest, from a stream of objects of interest which have passed through an inspection station.

Abstract: A sorting apparatus is described and which includes an inspection station; a multiplicity of electromagnetic radiation emitters and detectors; an optical filter which is positioned in front of the electromagnetic radiation detectors, and which passes electromagnetic radiation having a given polarization; an ejector assembly positioned downstream from the inspection station for removing defective objects of interest which are identified; and a computer/controller for selectively energizing the electromagnetic radiation emitter, and detector, and rendering the ejector assembly operational to remove defective objects of interest, from a stream of objects of interest which have passed through an inspection station.

Abstract: An apparatus and method for selectively removing or sorting undesirable articles wherein a product stream is transported by a conveyor, and then interrogated by an optical scanner and sorting processor to inspect and label the articles according to user specified criteria. Articles labeled or classified as undesirable articles are removed by an ejector or removal station while desirable or acceptable articles are passed.

Abstract: An apparatus for classifying articles may include a frame connected to (1) transport means for directing articles to create a product stream, (2) an emitter section having a radiation source and (3) a detection section for detecting a portion of radiation reflected by articles. The detection section may include first detection means for converting radiant power of reflected radiation having a first polarization state into a first electrical signal, second detection means for converting radiant power of reflected radiation having a second polarization state into a second electrical signal, and third detection means for converting radiant power of reflected radiation into a third electrical signal. Control circuitry, which may receive the electrical signals, may include decision means for generating a selection signal. Selection means may separate an article from the product stream according to the received selection signal from the control circuitry.

Abstract: An electromagnetic energy measurement apparatus and method for measuring first, second, and third wavelength components includes first and second coated optical elements having non-parallel surfaces. Proper selection of the parameters of the optical elements reduces the level of coma and astigmatism in the apparatus. Additionally, filters pass the first, second, and third wavelength components to first, second, and third sensors. Improvement in the alignment of the field of view between sensors is realized by applying an adjustable compressive force on the filters to individually adjust the field of view.

Abstract: An electromagnetic energy measurement apparatus and method for measuring first, second, and third wavelength components includes first and second coated optical elements having non-parallel surfaces. Proper selection of the parameters of the optical elements reduces the level of coma and astigmatism in the apparatus. Additionally, filters pass the first, second, and third wavelength components to first, second, and third sensors. Improvement in the alignment of the field of view between sensors is realized by applying an adjustable compressive force on the filters to individually adjust the field of view.

Abstract: A method for sorting products including the steps of conveying the products in a product stream, scanning the products in the product stream casting light onto the products on the basis that certain products will emit light, observing emitted light from the products, making a selection of certain products from the product stream as a function of the observed light, and separating certain products from the product stream as a function of the selection. A device is provided that is arranged to sort the products according to the method of the invention and includes a light device that is arranged to cast light onto products and an observation device that is arranged to observe light emitted from the products. A selection device is also provided that is arranged to make a selection of whether to separate certain products from the product stream observed by the observation device.