Patents by Inventor Carlo MARCHETTI

Carlo MARCHETTI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for treating diabetes
    Patent number: 12569463
    Abstract: The present invention is directed to a method for treating diabetes. The method comprises administering to a subject in need thereof dapansutrile, or a pharmaceutically acceptable solvate thereof, in an effective amount. Oral administration is a preferred route of administration.
    Type: Grant
    Filed: September 22, 2022
    Date of Patent: March 10, 2026
    Assignee: OLATEC THERAPEUTICS, INC.
    Inventors: Charles A. Dinarello, Carlo Marchetti, Marc Y. Donath
  • Methods for treating cardiovascular diseases
    Patent number: 12318361
    Abstract: The present invention is directed to a method for treating cardiovascular diseases such as acute myocardial infarction, atherosclerosis, heart failure, stroke, thrombosis, carditis (including acute myocarditis, acute pericarditis and complicated pericarditis), cardiac allograft rejection, cardiomyopathy, and peripheral vascular diseases. The method comprises administering to a subject in need thereof dapansutrile, in an effective amount. A preferred route of administration is oral administration.
    Type: Grant
    Filed: February 7, 2023
    Date of Patent: June 3, 2025
    Assignee: OLATEC THERAPEUTICS, INC.
    Inventors: Carlo Marchetti, Charles A. Dinarello
  • METHODS FOR TREATING PANCREATIC CANCER
    Publication number: 20240358669
    Abstract: The present invention provides a method for treating pancreatic cancer. The method comprises administering to a subject in need thereof an effective amount of dapansutrile. Preferred route of administration of dapansutrile is oral administration. The present invention also provides a combination treatment of pancreatic cancer, by administering dapansutrile and gemcitabine to the patient in need thereof.
    Type: Application
    Filed: July 9, 2024
    Publication date: October 31, 2024
    Inventors: Charles A. Dinarello, Carlo Marchetti
  • Methods for treating melanoma
    Patent number: 11857529
    Abstract: The present invention is directed to a method for preventing and/or treating melanoma such as superficial spreading melanoma, nodular melanoma, lentigo maligna melanoma, and acral lentiginous melanoma. The method comprises administering to a subject in need thereof an effective amount of dapansutrile. The method optionally comprising co-administering anti-PD-1 antibody with dapansutrile. A preferred route of administration is oral administration.
    Type: Grant
    Filed: September 15, 2020
    Date of Patent: January 2, 2024
    Assignee: OLATEC THERAPEUTICS, INC.
    Inventors: Carlo Marchetti, Charles A. Dinarello
  • METHODS FOR TREATING CARDIOVASCULAR DISEASES
    Publication number: 20230277496
    Abstract: The present invention is directed to a method for treating cardiovascular diseases such as acute myocardial infarction, atherosclerosis, heart failure, stroke, thrombosis, carditis (including acute myocarditis, acute pericarditis and complicated pericarditis), cardiac allograft rejection, cardiomyopathy, and peripheral vascular diseases. The method comprises administering to a subject in need thereof dapansutrile, in an effective amount. A preferred route of administration is oral administration.
    Type: Application
    Filed: February 7, 2023
    Publication date: September 7, 2023
    Inventors: Carlo Marchetti, Charles A. Dinarello
  • Methods for treating cardiovascular diseases
    Patent number: 11576888
    Abstract: The present invention is directed to a method for treating cardiovascular diseases such as acute myocardial infarction, atherosclerosis, heart failure, stroke, thrombosis, carditis (including acute myocarditis, acute pericarditis and complicated pericarditis), cardiac allograft rejection, cardiomyopathy, and peripheral vascular diseases. The method comprises administering to a subject in need thereof dapansutrile, in an effective amount. A preferred route of administration is oral administration.
    Type: Grant
    Filed: June 25, 2019
    Date of Patent: February 14, 2023
    Assignee: OLATEC THERAPEUTICS LLC
    Inventors: Carlo Marchetti, Charles A. Dinarello
  • METHOD FOR TREATING ASTHMA
    Publication number: 20220087969
    Abstract: The present invention is directed to a method for treating Asthma. The method comprises administering to a subject in need thereof 3-methanesulfonylpropionitrile (dapansutrile), or a pharmaceutically acceptable solvate thereof, in an effective amount. The preferred route of administration is oral administration or local administration.
    Type: Application
    Filed: December 2, 2021
    Publication date: March 24, 2022
    Inventors: Charles A. Dinarello, Carlo Marchetti
  • METHODS FOR TREATING MELANOMA
    Publication number: 20200405681
    Abstract: The present invention is directed to a method for preventing and/or treating melanoma such as superficial spreading melanoma, nodular melanoma, lentigo maligna melanoma, and acral lentiginous melanoma. The method comprises administering to a subject in need thereof an effective amount of dapansutrile. The method optionally comprising co-administering anti-PD-1 antibody with dapansutrile. A preferred route of administration is oral administration.
    Type: Application
    Filed: September 15, 2020
    Publication date: December 31, 2020
    Inventors: Carlo Marchetti, Charles A. Dinarello
  • METHODS FOR TREATING CARDIOVASCULAR DISEASES
    Publication number: 20190307718
    Abstract: The present invention is directed to a method for treating cardiovascular diseases such as acute myocardial infarction, atherosclerosis, heart failure, stroke, thrombosis, carditis (including acute myocarditis, acute pericarditis and complicated pericarditis), cardiac allograft rejection, cardiomyopathy, and peripheral vascular diseases. The method comprises administering to a subject in need thereof dapansutrile, in an effective amount. A preferred route of administration is oral administration.
    Type: Application
    Filed: June 25, 2019
    Publication date: October 10, 2019
    Inventor: Carlo MARCHETTI