Abstract: Provided are methods of treating an injury to the nervous system in a subject comprising administering to the subject an effective amount of boldine, a boldine analog, or a pharmaceutically-acceptable salt thereof. Also provided are methods of improving voluntary muscle control and methods of treating neuropathic pain in a subject having an injury to the nervous system. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.

Abstract: Provided are methods of treating an injury to the nervous system in a subject comprising administering to the subject an effective amount of boldine, a boldine analog, or a pharmaceutically-acceptable salt thereof. Also provided are methods of improving voluntary muscle control and methods of treating neuropathic pain in a subject having an injury to the nervous system. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.

Abstract: An absorbent article selected from a sanitary napkin, an incontinence pad and a pantyliner, comprising a topsheet layer a backsheet layer a fastening adhesive applied on the backsheet garment facing surface, wherein at least a portion of said fastening adhesive (PFA) is applied in a pattern and wherein said backsheet layer is a plastic film having a basis weight of less than 20 gsm.

Abstract: A disposable absorbent article is described. The disposable absorbent article includes a topsheet forming at least a portion of a wearer-facing surface of the absorbent article; a backsheet forming at least a portion of a garment-facing surface of the absorbent article; an absorbent core disposed between the topsheet and the backsheet; a front end portion, a rear end portion, and a central portion; and a first adhesive for attachment of the disposable absorbent article to an undergarment. The first adhesive is disposed on the garment-facing surface of the front end portion and the rear end portion and not on the central portion. The absorbent article exhibits a peel force of at least 1.0 N, about 1.1 N or about 1.2 N in accordance with the Peel Force test and leaves no residue on an undergarment in accordance with the Adhesive Residue test.

Abstract: An absorbent article selected from a sanitary napkin, an incontinence pad and a pantyliner, comprising a topsheet layer a backsheet layer a fastening adhesive applied on the backsheet garment facing surface, wherein at least a portion of said fastening adhesive (PFA) is applied in a pattern and wherein said backsheet layer is a plastic film having a basis weight of less than 20 gsm.

Abstract: Provided are methods of treating an injury to the nervous system in a subject comprising administering to the subject an effective amount of boldine, a boldine analog, or a pharmaceutically-acceptable salt thereof. Also provided are methods of improving voluntary muscle control and methods of treating neuropathic pain in a subject having an injury to the nervous system. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.

Abstract: An absorbent article selected from a sanitary napkin, an incontinence pad and a pantyliner, comprising a topsheet layer a backsheet layer a fastening adhesive applied on the backsheet garment facing surface, wherein at least a portion of said fastening adhesive (PFA) is applied in a pattern and wherein said backsheet layer is a plastic film having a basis weight of less than 20 gsm.

Abstract: A method of determining of the presence or absence of a target RNA component in a sample, the method comprising steps of: (a) contacting the sample with a composition comprising (i) a quaternary ammonium compound or a precursor thereof, which should extract/release the nucleic acid from the sample; (b) optionally storing and/or transporting the composition obtained in step (a); (c) contacting the composition obtained in step (a) with a composition comprising a proteinaceous washing agent, e.g. BSA or casein for stabilizing the RNA for transport and/or storage; and (d) using the composition obtained in step (c) in an amplification method, e.g. RT-PCR.

Abstract: A method of extracting DNA and/or RNA from a cell or capsid, the method comprising steps of: (a) contacting a composition comprising the cell or capsid with a composition comprising (ii) a quaternary ammonium compound or a precursor thereof; and (b) contacting the composition obtained in step (a) with a composition comprising a proteinaceous washing agent.

Abstract: A process for manufacturing a disposable absorbent article is disclosed. The method includes providing a first layer having a first surface and an opposing second surface; color printing the first layer on at least one of the first or second surface; providing a second layer having a first and an opposing second surface; providing a topsheet, an absorbent core, and a backsheet; and placing the first layer and second layer between a topsheet and an absorbent core such that the color printing is visible through a wearer-facing surface of the disposable absorbent article.

Abstract: A method (e.g. high resolution melting analysis) of determining of the presence or absence of a target nucleic acid in a sample, e.g. a biological sample, the method comprising steps of:?(a) contacting the sample with a composition comprising?(i) a quaternary ammonium compound, e.g. 3-(trimethoxysilyl) propyl-dimethyl octadecyl ammonium chloride (3-TPAC) or a precursor thereof, in order to release the nucleic acids from said sample; and?(b) contacting the sample with a probe which is capable of interacting with the nucleic acid sequence; and?(c) observing and/or measuring a property of the sample, e.g. fluorescence from a dsDNA binding dye.

Abstract: A method of extracting DNA and/or RNA from a cell or capsid, the method comprising steps of: (a) contacting a composition comprising the cell or capsid with a composition comprising (ii) a quaternary ammonium compound or a precursor thereof; and (b) contacting the composition obtained in step (a) with a composition comprising a proteinaceous washing agent.

Abstract: A method of stabilising genetic material in a sample, the method comprising steps of: (a) contacting the sample with a composition comprising a quaternary ammonium compound or a precursor thereof.

Abstract: A method (e.g. high resolution melting analysis) of determining of the presence or absence of a target nucleic acid in a sample, e.g. a biological sample, the method comprising steps of:?(a) contacting the sample with a composition comprising?(i) a quaternary ammonium compound, e.g. 3-(trimethoxysilyl) propyl-dimethyl octadecyl ammonium chloride (3-TPAC) or a precursor thereof, in order to release the nucleic acids from said sample; and?(b) contacting the sample with a probe which is capable of inter-acting with the nucleic acid sequence; and?(c) observing and/or measuring a property of the sample, e.g. fluorescence from a dsDNA binding dye.

Abstract: A method of determining of the presence or absence of a target RNA component in a sample, the method comprising steps of: (a) contacting the sample with a composition comprising (i) a quaternary ammonium compound or a precursor thereof, which should extract/release the nucleic acid from the sample; (b) optionally storing and/or transporting the composition obtained in step (a); (c) contacting the composition obtained in step (a) with a composition comprising a proteinaceous washing agent, e.g. BSA or casein for stabilizing the RNA for transport and/or storage; and (d) using the composition obtained in step (c) in an amplification method, e.g. RT-PCR.

Abstract: A process for manufacturing a disposable absorbent article is disclosed. The method includes providing a first layer having a first surface and an opposing second surface; color printing the first layer on at least one of the first or second surface; providing a second layer having a first and an opposing second surface; providing a topsheet, an absorbent core, and a backsheet; and placing the first layer and second layer between a topsheet and an absorbent core such that the color printing is visible through a wearer-facing surface of the disposable absorbent article.

Abstract: A process for manufacturing a disposable absorbent article is disclosed. The method includes providing a first nonwoven layer with bi-component fibers and having a first surface and an opposing second surface; color printing the first nonwoven layer on at least one of the first or second surface; providing a second nonwoven layer with bi-component fibers and a first and an opposing second surface; joining the first and the second nonwoven layers together to form a laminate structure, wherein the color printing faces the second nonwoven layer; providing a topsheet, an absorbent core, and a backsheet; and placing the laminate between a topsheet and an absorbent core such that the color printing is visible through the topsheet.

Abstract: An absorbent article selected from a sanitary napkin, an incontinence pad and a pantyliner, comprising a topsheet layer a backsheet layer a fastening adhesive applied on the backsheet garment facing surface, wherein at least a portion of said fastening adhesive (PFA) is applied in a pattern and wherein said backsheet layer is a plastic film having a basis weight of less than 20 gsm.

Abstract: An article having a longitudinal axis and a lateral axis, the article comprising a topsheet and a backsheet, wherein the topsheet comprises an apertured film and the backsheet comprises a film, wherein the topsheet film and the backsheet film are bonded via a plurality of adhesive stripes.

Abstract: A process for manufacturing a disposable absorbent article is disclosed. The method includes providing a first nonwoven layer with bi-component fibers and having a first surface and an opposing second surface; color printing the first nonwoven layer on at least one of the first or second surface; providing a second nonwoven layer with bi-component fibers and a first and an opposing second surface; joining the first and the second nonwoven layers together to form a laminate structure, wherein the color printing faces the second nonwoven layer; providing a topsheet, an absorbent core, and a backsheet; and placing the laminate between a topsheet and an absorbent core such that the color printing is visible through the topsheet.