Abstract: The present application discloses a vibrational spectroscopy method for diagnosing Alzheimer's disease in a subject comprising the steps of a) determining in a Raman spectrum of a biofluid from said subject or in a sample derived from said biofluid the intensity of a Raman band around 1256 cm?1; and b) comparing the intensity value obtained in step a) with a reference value, wherein an increase in the value of said Raman band intensity with respect to the reference value is indicative that the subject suffers Alzheimer's disease. The application also discloses an apparatus for plasma sample analysis, a computer program, a data carrier and to a therapy suitable for treating Alzheimer's disease.

Abstract: The invention relates to methods for determining the likelihood that a patient with mild cognitive impairment develops Alzheimer's disease based on the determination of the levels of different metabolites, including amino acids, proteins and lipids. The invention also provides a method for diagnosing Alzheimer's disease or mild cognitive impairment in a subject based on the determination of the above metabolites.

Abstract: A new route of synthesis of the compound Aliskiren of formula (I), used in the treatment of hypertension, is described.

Abstract: A new route of synthesis of the compound Aliskiren of formula (I), used in the treatment of hypertension, is described.

Abstract: The present invention relates to adipose stem cell compositions, methods for making said compositions, kits comprising said compositions and uses of said compositions in the therapy of diseases.

Abstract: An injection device 100 comprises a housing 102 which is adapted to receive a fluid container 120. The housing 102 is also adapted to hold the fluid container 120 stationary relative to the housing 102 during use of the device 100. The injection device 100 also comprises a discharge nozzle 128 which is movable between a first retracted position in which the discharge nozzle 128 is contained within the housing 102 and a first extended position in which the discharge nozzle 128 has moved relative to the fluid container 120 and extends from the housing 102 through an exit aperture 138 of the housing 102. The fluid container 120 and discharge nozzle 128 are in fluid communication with each other in the first extended position. Extension of the discharge nozzle and expulsion of a predetermined and fixed quantity of fluid can be achieved in a single continuous action.