Patents by Inventor Carlos A. Muro-Cacho

Carlos A. Muro-Cacho has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of predicting responsiveness to chemotherapeutic agents and selecting treatments
    Patent number: 8133692
    Abstract: Methods are provided for predicting responsiveness of cancer cells to chemotherapy by measuring the level of phosphorylated Stat or the level of expression of Survivin in a cancer and comparing the level in the cancer cell to the respective level in a control. Also provided are methods of selecting a chemotherapeutic treatment for a subject diagnosed with cancer by measuring the level of phosphorylated Stat or the level of expression of Survivin in a cancer and comparing the level in the cancer cell to the respective level in a control. Kits for performing the methods are also provided. Methods for modulating Survivin-dependent apoptosis in a cancer cell are also disclosed.
    Type: Grant
    Filed: July 20, 2006
    Date of Patent: March 13, 2012
    Assignee: University of South Florida
    Inventors: Richard Jove, Susan E. Minton, Carlos A. Muro-Cacho, Daniel Sullivan, Eric Bruce Haura, Gerold Bepler
  • Methods of predicting responsiveness to chemotherapeutic agents and selecting treatments
    Publication number: 20070031871
    Abstract: Methods are provided for predicting responsiveness of cancer cells to chemotherapy by measuring the level of phosphorylated Stat or the level of expression of Survivin in a cancer and comparing the level in the cancer cell to the respective level in a control. Also provided are methods of selecting a chemotherapeutic treatment for a subject diagnosed with cancer by measuring the level of phosphorylated Stat or the level of expression of Survivin in a cancer and comparing the level in the cancer cell to the respective level in a control. Kits for performing the methods are also provided. Methods for modulating Survivin-dependent apoptosis in a cancer cell are also disclosed.
    Type: Application
    Filed: July 20, 2006
    Publication date: February 8, 2007
    Applicant: University of South Florida
    Inventors: Richard Jove, Susan Minton, Carlos Muro-Cacho, Daniel Sullivan, Eric Haura, Gerold Bepler