Patents by Inventor Carlos A. Velikovsky

Carlos A. Velikovsky has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • High affinity recombinant sea lamprey antibodies selected by a Yeast Surface Display platform
    Patent number: 9127087
    Abstract: The present invention relates to a Yeast Surface Display (YSD) vector for expression of VLR proteins by yeast, wherein the vector includes nucleotide sequences encoding segments of yeast flocculation proteins Flo1p, such as the leader and C-terminal segments, a homologous recombinant cassette and a geneticin/kanamycin resistance gene. The vector can be used for expression of VLR that may be effective in diagnostic applications (e.g., protein chip, immunohistochemistry, flow cytometry), immunoaffinity purification, and for engineering novel fusion proteins.
    Type: Grant
    Filed: November 25, 2009
    Date of Patent: September 8, 2015
    Assignee: UNIVERSITY OF MARYLAND, BALTIMORE
    Inventors: Zeev Pancer, Roy A. Mariuzza, Satoshi Tasumi, Carlos A. Velikovsky
  • HIGH AFFINITY RECOMBINANT SEA LAMPREY ANTIBODIES SELECTED BY A YEAST SURFACE DISPLAY PLATFORM
    Publication number: 20110230374
    Abstract: The present invention relates to a Yeast Surface Display (YSD) vector for expression of VLR proteins by yeast, wherein the vector includes nucleotide sequences encoding segments of yeast flocculation proteins FloIp, such as the leader and C-terminal segments, a homologous recombinant cassette and a geneticin/kanamycin resistance gene. The vector can be used for expression of VLR that may be effective in diagnostic applications (e.g., protein chip, immunohistochemistry, flow cytometry), immunoaffinity purification, and for engineering novel fusion proteins.
    Type: Application
    Filed: November 25, 2009
    Publication date: September 22, 2011
    Inventors: Zeev Pancer, Roy A. Mariuzza, Satoshi Tasumi, Carlos A. Velikovsky