Abstract: The present invention relates to aqueous stable antibody compositions suitable for long term storage, in particular comprising antibodies against Tumor Necrosis Factor alpha (anti-TNF?). More specifically, it provides an aqueous composition comprising: —an anti-TNF? antibody; —a buffer selected from the list consisting of an acetate buffer, a citrate buffer, and a citrate-acetate buffer; and —an excipient, wherein said excipient is at least selected from a disaccharide, a sugar alcohol and a combination thereof; wherein when the buffer comprises or consists of an acetate buffer, said composition comprises a disaccharide at a concentration of less than 240 mM; wherein when the buffer comprises or consists of a citrate or a citrate-acetate buffer, said composition comprises a sugar alcohol at a concentration from 50 mM to 300 mM; and wherein the pH of the composition is from pH 4.0 to pH 7.0.

Abstract: The present invention relates to aqueous stable pharmaceutical compositions suitable for storage of polypeptides that contain TNFR:Fc.