Patents by Inventor Carlos CORDOVILLA LOSADA

Carlos CORDOVILLA LOSADA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process and intermediates for the synthesis of obeticholic acid and derivatives thereof
    Patent number: 11104702
    Abstract: A process for the preparation of obeticholic acid and derivatives thereof by: (a) hydrogenation of the double bond and reductive opening of the epoxide of a compound of formula (II) or a salt or solvate thereof to obtain a compound of formula (IIIa) and/or (IIIb), or salts or solvates thereof and (b) conversion of a compound of formula (IIIa) and/or a compound of formula (IIIb), or a salt or solvate thereof, into a compound of formula (I), or a salt or solvate thereof
    Type: Grant
    Filed: June 22, 2018
    Date of Patent: August 31, 2021
    Assignee: CRYSTAL PHARMA, S.A.U.
    Inventors: Ignacio Herráiz Sierra, Yolanda Fernández Sainz, Carlos Cordovilla Losada, Alfonso Pérez Encabo, José Angel Turiel Hernandez
  • PROCESS AND INTERMEDIATES FOR THE SYNTHESIS OF OBETICHOLIC ACID AND DERIVATIVES THEREOF
    Publication number: 20200165289
    Abstract: A process for the preparation of obeticholic acid and derivatives thereof by: (a) hydrogenation of the double bond and reductive opening of the epoxide of a compound of formula (II) or a salt or solvate thereof to obtain a compound of formula (IIIa) and/or (IIIb), or salts or solvates thereof and (b) conversion of a compound of formula (IIIa) and/or a compound of formula (IIIb), or a salt or solvate thereof, into a compound of formula (I), or a salt or solvate thereof
    Type: Application
    Filed: June 22, 2018
    Publication date: May 28, 2020
    Inventors: Ignacio HERRÁIZ SIERRA, Yolanda FERNANDEZ SAINZ, Carlos CORDOVILLA LOSADA, Alfonso PÉREZ ENCABO, José Angel TURIEL HERNANDEZ