Patents by Inventor Carlos David Esteban Nieto

Carlos David Esteban Nieto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of the nucleotide sequence of the promoter of the lactose operon of Lactobacillus casei to regulate the genic expression through an anti-terminator protein
    Publication number: 20030100067
    Abstract: This invention describes the use of a method for the expression of proteins in bacteria, which is based on the inducer effect, for example, of a carbohydrate on the anti-terminating activity of a protein of the family of anti-terminators, B1gG/SacY. The procedure has been tested with the system derived from the operon lacTEGF, inducible by lactose in Lactobacillus casei, for the expression of proteins of different kinds. In the invention are included examples of expression in multicopy plasmids or of integration in the chromosomal operon lacTEGF, thus achieving the coordinated expression of the desired genes together with those that code the enzymes of the metabolism of the lactose.
    Type: Application
    Filed: October 7, 2002
    Publication date: May 29, 2003
    Inventors: Maria Jose Gosalbes Soler, Isabel Perez Arellano, Carlos David Esteban Nieto, Jose Luis Galan Asuncion, Gaspar Perez Martinez