Abstract: A safety method for a railway network that is divided into section segments by way of section elements and which can be traveled by vehicles in accordance with data from a section atlas. The vehicles request steps for allocation as a track element from selected section elements. Each of the selected section elements autonomously allocates itself as a track element under specified conditions for each requesting vehicle. In order to be able to inform the vehicle or the vehicle operators thereof about changed section characteristics better and more quickly, for the section elements, the vehicles store manually entered and/or manually released dynamic driving operation data as a dynamic component of the section atlas in parts related to the section elements.

Abstract: A protection method for a railway network, which is divided into section segments by section elements and can be traveled upon by vehicles. In order to optimize the vehicle sequence in the railway network, different train sequence point types are specified and different braking curves of the same braking curve type are provided by the vehicles. Each of the different braking curves of the same braking curve type of the particular vehicle is associated with one of the different train sequence point types.

Abstract: A protection method for a railway network which is divided into track sections by track elements, and which can be traveled on by vehicles. The vehicles request steps for assignment from selected track elements to form travel path elements. In order to optimize the train service, each of the selected track elements provides at least one signal for each vehicle that requests at least one of the steps for assignment as a travel path element from same. A protection system for a railway network is configured to carry out the protection method.

Abstract: A safety method is provided for a railway network which is divided into track segments by track elements and can be traveled by vehicles. In the method the vehicles request, from selections of the track elements, steps for assignment as a travel path element. Each of the selected track elements automatically assigns itself as a travel path element for each vehicle that requests the steps for assignment as a travel path element, under predetermined conditions. For temporal optimization of the assignment of the track elements as travel path elements, the respective track element automatically assigns itself to the respective vehicle, in that in reaction to a first request of the respective vehicle in a demand type requested by the respective vehicle, the track element carries out its approval as a travel path element for the respective vehicle.

Abstract: A rail network is divided by track elements into track sections on which vehicles can travel. The vehicles request, from selected track elements, steps for assignment as a route element. Each of the selected track elements is respectively automatically assigned as a route element, under predefined conditions, for each vehicle which requests the steps for assignment as a route element to it, and outputs an assignment confirmation to the respective vehicle. For better protection of construction and/or maintenance work in the hazardous area of the rail network at least one of the track elements forms, after its integration into the rail network, a working zone and does not output the assignment confirmation for the respective vehicle until after an assignment release is input. The track element is provided with a release device into which the assignment release is input manually.

Abstract: A safety method is provided for a railway network that is divided into track sections by track elements, and can be travelled by vehicles in accordance with data from components of a track atlas. The vehicles request steps, from selections of the track elements, for assignment as a travel path element, and in which each of the selected track elements automatically assigns itself as a travel path element for each vehicle that requests the steps for assignment as a travel path element, under predetermined conditions. In order to optimize the loading of the track atlas relating to each vehicle, the data at least of one of the components of the track atlas is stored locally by the track elements in parts relating to the track elements in the form of datasets. A safety system for the railway network implements the safety method.

Abstract: A protection method for a railway network which is divided into track sections by track elements, and which can be traveled on by vehicles. The vehicles request steps for assignment from selected track elements to form travel path elements. In order to optimize the train service, each of the selected track elements provides at least one signal for each vehicle that requests at least one of the steps for assignment as a travel path element from same. There is also disclosed a protection system for a railway network.

Abstract: A safety method for a railway network that is divided into section segments by way of section elements and which can be traveled by vehicles in accordance with data from a section atlas. The vehicles request steps for allocation as a track element from selected section elements. Each of the selected section elements autonomously allocates itself as a track element under specified conditions for each requesting vehicle. In order to be able to inform the vehicle or the vehicle operators thereof about changed section characteristics better and more quickly, for the section elements, the vehicles store manually entered and/or manually released dynamic driving operation data as a dynamic component of the section atlas in parts related to the section elements.

Abstract: A safety method is provided for a railway network which is divided into track segments by track elements and can be traveled by vehicles. In the method the vehicles request, from selections of the track elements, steps for assignment as a travel path element. Each of the selected track elements automatically assigns itself as a travel path element for each vehicle that requests the steps for assignment as a travel path element, under predetermined conditions. For temporal optimization of the assignment of the track elements as travel path elements, the respective track element automatically assigns itself to the respective vehicle, in that in reaction to a first request of the respective vehicle in a demand type requested by the respective vehicle, the track element carries out its approval as a travel path element for the respective vehicle.

Abstract: A rail network is divided by track elements into track sections on which vehicles can travel. The vehicles request, from selected track elements, steps for assignment as a route element. Each of the selected track elements is respectively automatically assigned as a route element, under predefined conditions, for each vehicle which requests the steps for assignment as a route element to it, and outputs an assignment confirmation to the respective vehicle. For better protection of construction and/or maintenance work in the hazardous area of the rail network at least one of the track elements forms, after its integration into the rail network, a working zone and does not output the assignment confirmation for the respective vehicle until after an assignment release is input. The track element is provided with a release device into which the assignment release is input manually.

Abstract: A protection method for a railway network, which is divided into section segments by section elements and can be traveled upon by vehicles. In order to optimize the vehicle sequence in the railway network, different train sequence point types are specified and different braking curves of the same braking curve type are provided by the vehicles. Each of the different braking curves of the same braking curve type of the particular vehicle is associated with one of the different train sequence point types.

Abstract: Variolin derivatives of formula (5) are provided, wherein the substituent groups defined by X2, R1, R2, R3, R6, R7, and R12 are each independently selected from the group consisting of H, OH, OR?, SH, SR?, SOR?, SO2R?, NO2, NH2, NHR?, N(R?)2, NHCOR?, NHSO2R?, CN, halogen, ?O, C(?O)H, C(?O)R?, CO2H, CO2R?, carboxyalkyl, C1-C12 alkyl, C2-C12 alkenyl, C2-C12 alkynyl, substituted or unsubstituted aryl, substituted or unsubstituted aralkyl and substituted or unsubstituted heteroaromatic; wherein each of the R? groups is independently selected from the group consisting of H, OH, SH, NO2, NH2, CN, halogen, ?O, C(?O)H, C(?O)CH3, CO2H, CO2CH3, C1-C12 alkyl, C2-C12 alkenyl, C2-C12 alkynyl, aryl, aralkyl and heteroaromatic; wherein the pairs of groups of R1 and R2, R2 and R3, R3 and R12, R12 and R6, or R6 and R7 may be joined into a carbocyclic or heterocyclic ring system.

Abstract: Variolin derivatives of formula (5) are provided, wherein the substituent groups defined by X2, R1, R2, R3, R6, R7, and R12 are each independently selected from the group consisting of H, OH, OR?, SH, SR?, SOR?, SO2R?, NO2, NH2, NHR?, N(R?)2, NHCOR?, NHSO2R?, CN, halogen, ?O, C(?O)H, C(?O)R?, CO2H, CO2R?, carboxyalkyl, C1-C12 alkyl, C2-C12 alkenyl, C2-C12 alkynyl, substituted or unsubstituted aryl, substituted or unsubstituted aralkyl and substituted or unsubstituted heteroaromatic; wherein each of the R? groups is independently selected from the group consisting of H, OH, SH, NO2, NH2, CN, halogen, ?O, C(?O)H, C(?O)CH3, CO2H, CO2CH3, C1-C12 alkyl, C2-C12 alkenyl, C2-C12 alkynyl, aryl, aralkyl and heteroaromatic; wherein the pairs of groups of R1 and R2, R2 and R3, R3 and R12, R12 and R6, or R6 and R7 may be joined into a carbocyclic or heterocyclic ring system.

Abstract: Compounds of the general formula (I) or a pharmaceutically acceptable salt, derivative, prodrug or stereoisomer thereof are provided: wherein the substituent groups defined by R are each independently selected from the group consisting of H, SiR?3, SOR?, SO2X, C(?O)R?, C(?O)OR?, C(?O)NR?, substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl, substituted or unsubstituted alkynyl, aryl, heteroaryl or aralkyl; the group R? is selected from substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl, substituted or unsubstituted alkynyl, aminoalkyl, aryl, aralkyl and heterocyclic groups; and the group R? is selected from the group consisting of H, OH, OR?, OCOR?, SH, SR?, SOR?, SO2R?, NO2, NH2, NHR?, N(R?)2, NHCOR?, N(COR?)2, NHSO2R?, CN, halogen, C(?O)H, C(?O)R?, CO2H, CO2R?, CH2OR, substituted or unsubstituted alkyl, substituted or unsubstituted haloalkyl, substituted or unsubstituted alkenyl, substituted or unsubstituted alkylidene, substituted or unsubstituted alkynyl, substit

Abstract: Variolin derivatives of formula (5) are provided, wherein the substituent groups defined by X2, R1, R2, R3, R6, R7 and R12 are each independently selected from the group consisting of H, OH, OR?, SH, SR?, SOR?, SO2R?, NO2, NH2, NHR?, N(R?)2, NHCOR?, NHSO2R?, CN, halogen, ?O, C(?O)H, C(?O)R?, CO2H, CO2R?, carboxyalkyl, C1-C12 alkyl, C2-C12 alkenyl, C2-C12 alkynyl, substituted or unsubstituted aryl, substituted or unsubstituted aralkyl and substituted or unsubstituted heteroaromatic; wherein each of the R? groups is independently selected from the group consisting of H, OH, SH, NO2, NH2, CN, halogen, ?O, C(?O)H, C(?O)CH3, CO2H, CO2CH3, C1-C12 alkyl, C2-C12 alkenyl, C2-C12alkynyl, aryl, aralkyl and heteroaromatic; wherein the pairs of groups R1 and R2, R2 and R3, R3 and R12, R12 and R6, or R6 and R7 may be joined into a carbocyclic or heterocyclic ring system.

Abstract: Compounds of the general formula (I) or a pharmaceutically acceptable salt, derivative, prodrug or stereoisomer thereof are provided: wherein the substituent groups defined by R are each independently selected from the group consisting of H, SiR?3, SOR?, SO2X, C(?O)R?, C(?O)OR?, C(?O)NR?, substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl, substituted or unsubstituted alkynyl, aryl, heteroaryl or aralkyl; the group R? is selected from substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl, substituted or unsubstituted alkynyl, aminoalkyl, aryl, aralkyl and heterocyclic groups; and the group R? is selected from the group consisting of H, OH, OR?, OCOR?, SH, SR?, SOR?, SO2R?, NO2, NH2, NHR?, N(R?)2, NHCOR?, N(COR?)2, NHSO2R?, CN, halogen, C(?O)H, C(?O)R?, CO2H, CO2R?, CH2OR, substituted or unsubstituted alkyl, substituted or unsubstituted haloalkyl, substituted or unsubstituted alkenyl, substituted or unsubstituted alkylidene, substituted or unsubstituted alkynyl, substit

Abstract: Compounds of the general formula (I) or pharmaceutically acceptable salt, derivative, prodrug or stereoisomer thereof are provided: wherein the substituent groups defined by R are each independently selected from the group consisting of H, SiR?3, SOR?, SO2X, C(?O)R?, C(?O)OR?, C(?O)NR?, substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl, substituted or unsubstituted alkynyl, aryl, heteroaryl or aralkyl; the group R? is selected from substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl, substituted or unsubstituted alkynyl, aminoalkyl, aryl, aralkyl and heterocyclic groups; and the group R? is selected from the group consisting of H, OH, OR?, OCOR?, SH, SR?, SOR?, SO2R?, NO2, NH2, NHR?, N(R?)2, NHCOR?, N(COR?)2, NHSO2R?, CN, halogen, C(=O)H, C(=O)R?, CO2H, CO2R?, CH2OR, substituted or unsubstituted alkyl, substituted or unsubstituted haloalkyl, substituted or unsubstituted alkenyl, substituted or unsubstituted alkylidene, substituted or unsubstituted alkynyl, substitut