Patents by Inventor Carlos E. Ibanez

Carlos E. Ibanez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Eukaryotic layered vector initiation systems
    Patent number: 7977091
    Abstract: The present disclosure provides compositions and methods for utilizing recombinant alphavirus vectors. Also disclosed are compositions and methods for making and utilizing eukaryotic layered vector initiation systems.
    Type: Grant
    Filed: August 10, 2009
    Date of Patent: July 12, 2011
    Assignee: Novartis Vaccines & Diagnostics, Inc.
    Inventors: Thomas W. Dubensky, Jr., John M Polo, Carlos E Ibanez, Stephen M. W. Chang, Douglas J Jolly, David A Driver, Barbara A Belli
  • Eukaryotic Layered Vector Initiation Systems
    Publication number: 20100173412
    Abstract: The present disclosure provides compositions and methods for utilizing recombinant alphavirus vectors.
    Type: Application
    Filed: August 10, 2009
    Publication date: July 8, 2010
    Inventors: Thomas W. Dubensky, JR., John M. Polo, Carlos E. Ibanez, Stephen M.W. Chang, Douglas J. Jolly, David A. Driver, Barbara A. Belli
  • Eukaryotic layered vector initiation systems
    Patent number: 7572628
    Abstract: The present invention provides compositions and methods for utilizing recombinant alphavirus vectors. Also disclosed are compositions and methods for making and utilizing eukaryotic layered vector initiation systems.
    Type: Grant
    Filed: January 16, 2003
    Date of Patent: August 11, 2009
    Assignee: Novartis Vaccines and Diagnostics, Inc.
    Inventors: Thomas W. Dubensky, Jr., John M. Polo, Carlos E. Ibanez, Stephen M. W. Chang, Douglas J. Jolly, David A. Driver, Barbara A. Belli
  • Methods for administration of recombinant gene delivery vehicles for treatment of hemophilia and other disorders
    Patent number: 6818439
    Abstract: Methods are provided for obtaining measurable levels of a protein, nucleic acid molecule, or enzymatic product in a bodily fluid or cells of a human, comprising the step of administering to a human a recombinant retroviral preparation having a titer on HT1080 cells of greater than 105 cfu/ml, wherein the recombinant retroviral preparation is capable of directing the expression of a protein, nucleic acid molecule, or enzyme which generates an enzymatic product, such that measurable levels of the protein, nucleic acid molecule, or enzymatic product may be obtained in the bodily fluid or cells of the human.
    Type: Grant
    Filed: December 30, 1997
    Date of Patent: November 16, 2004
    Assignee: Chiron Corporation
    Inventors: Douglas J. Jolly, Stephen Chang, James G. Respess, Nicholas J. DePolo, David Chi-Tang Hsu, Carlos E. Ibanez, Judith Greengard, Lee Will
  • Eukaryotic layered vector initiation systems
    Publication number: 20040029278
    Abstract: The present invention provides compositions and methods for utilizing recombinant alphavirus vectors. Also disclosed are compositions and methods for making and utilizing eukaryotic layered vector initiation systems.
    Type: Application
    Filed: May 17, 2002
    Publication date: February 12, 2004
    Applicant: Chiron Corporation
    Inventors: Thomas W. Dubensky, John M. Polo, Carlos E. Ibanez, Stephen M.W. Chang, Douglas J. Jolly, David A. Driver, Barbara A. Belli
  • Eukaryotic layered vector initiation systems
    Publication number: 20030232035
    Abstract: The present invention provides compositions and methods for utilizing recombinant alphavirus vectors. Also disclosed are compositions and methods for making and utilizing eukaryotic layered vector initiation systems.
    Type: Application
    Filed: January 16, 2003
    Publication date: December 18, 2003
    Inventors: Thomas W. Dubensky, John M. Polo, Carlos E. Ibanez, Stephen M.W. Chang, Douglas J. Jolly, David A. Driver, Barbara A. Belli
  • Methods of suppressing immune response by gene therapy
    Publication number: 20030091546
    Abstract: Tissue cells of an animal transformed with a multivalent recombinant vector construct are provided. The vector construct expresses a therapeutic protein and either (a) a second protein or active portion thereof capable of inhibiting MHC antigen presentation; (b) an antisense message capable of inhibiting MHC antigen presentation; or (c) a ribozyme capable of inhibiting MHC antigen presentation. Pharmaceutical compositions comprising such multivalent constructs are also provided. The transformed tissue cells are particularly useful within methods for suppressing an immune response.
    Type: Application
    Filed: June 26, 2002
    Publication date: May 15, 2003
    Inventors: Jack R. Barber, John F. Warner, Michael J. Irwin, Thomas W. Dubensky, Carlos E. Ibanez, Douglas J. Jolly
  • Recombinant alphavirus particles
    Patent number: 6376236
    Abstract: Disclosed are recombinant alphavirus particles comprising a) an alphavirus vector construct which directs the expression of a heterologous nucleic acid molecule; b) a capsid protein; and c) an envelope glycoprotein from a virus different from said alphavirus vector.
    Type: Grant
    Filed: January 22, 1999
    Date of Patent: April 23, 2002
    Assignee: Chiron Corporation
    Inventors: Thomas W. Dubensky, Jr., John M. Polo, Carlos E. Ibanez, David A. Driver
  • Alphavirus vector constructs
    Patent number: 5843723
    Abstract: The present invention provides compositions and method,, for utilizing recombinant alphavirus vectors.
    Type: Grant
    Filed: October 30, 1996
    Date of Patent: December 1, 1998
    Assignee: Chiron Corporation
    Inventors: Thomas W. Dubensky, Jr., John M. Polo, Carlos E. Ibanez, Stephen M. W. Chang, Douglas J. Jolly, David A. Driver, Barbara A. Belli
  • Alphavirus structural protein expression cassettes
    Patent number: 5789245
    Abstract: The present invention provides compositions and methods for utilizing recombinant alphavirus vectors. Also disclosed are compositions and methods for making and utilizing eukaryotic layered vector initiation systems.
    Type: Grant
    Filed: October 30, 1996
    Date of Patent: August 4, 1998
    Assignee: Chiron Corporation
    Inventors: Thomas W. Dubensky, Jr., John M. Polo, Carlos E. Ibanez, Stephen M. W. Chang, Douglas J. Jolly, David A. Driver